Protein Alignment Lcch3 and AgaP_AGAP001990

DIOPT Version :9

• Sequence 1: NP_996469.1
• Gene: Lcch3 / 32554
• FlyBaseID: FBgn0010240
• Length: 496
• Species: Drosophila melanogaster
• Sequence 2: XP_321068.3
• Gene: AgaP_AGAP001990 / 1281130
• VectorBaseID: AGAP001990
• Length: 212
• Species: Anopheles gambiae
• Alignment Length: 286
• Identity: 94/286 - (32%)
• Similarity: 129/286 - (45%)
• Gaps: 92/286 - (32%)

  Fly   218 DAELPQFTIIGYETNDRKERLATGVYQRLSLSFKLQRNIGYFVFQTYLPSILIVMLSWVSFWINH 282
            :.||||..|....|.|.....:||.:..|::.|.|:|.:||.:|.||:||.|||::||:||||..
Mosquito    10 EIELPQLDISNNYTTDCTIEYSTGNFTCLAVVFNLRRRLGYHLFHTYIPSALIVVMSWISFWIKP 74

  Fly   283 EATSARVALGITTVLTMTTISTGVRSSLPRISYVKAIDIYLVMCFVFVFAALLEYAAVNYTYWGK 347
            ||..|||.||:|::||:.|.:|..:.|||.:|||||||:::..|.||||.:|:|:|.|| .|.|.
Mosquito    75 EAIPARVTLGVTSLLTLATQNTQSQQSLPPVSYVKAIDVWMSSCSVFVFLSLMEFAVVN-NYMGP 138

  Fly   348 RAKKKIKKVKECCPGKIGKSERSETCSTTEDIIEL---------QDVRMSPIPSLRRGTYNATLD 403
            .|.|.:|          |.|:        ||:.|.         :|.|.|.:|  |..|:
Mosquito   139 VATKAMK----------GYSD--------EDLSEAIDFNKNGYNKDHRSSEVP--RYDTF----- 178

  Fly   404 SIGTETMNLGKFPPSFRITRNYGTGHSQLRRRAQRGISTRPRMLHALKRGASAIKATIPKIKDVN 468
            ..|.||                                       ||
Mosquito   179 CHGRET---------------------------------------AL------------------ 186

  Fly   469 IIDKYSRMIFPISFLAFNLGYWLFYI 494
            .|||:||..||.||...|:.||..::
Mosquito   187 CIDKFSRFFFPFSFFILNVTYWTTFL 212

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Lcch3	NP_996469.1	LIC	15..493	CDD:273305	94/283 (33%)
		Neur_chan_LBD	47..256	CDD:280998	13/37 (35%)
		Neur_chan_memb	263..490	CDD:280999	76/235 (32%)
AgaP_AGAP001990	XP_321068.3	LGIC_ECD	<1..47	CDD:355788	12/36 (33%)
		LGIC_TM_anion	50..>136	CDD:349851	47/86 (55%)
		TM1 helix	53..73	CDD:349851	13/19 (68%)
		TM2 helix	82..103	CDD:349851	8/20 (40%)
		TM3 helix	113..135	CDD:349851	10/22 (45%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810