Protein Alignment Lcch3 and AgaP_AGAP010694

DIOPT Version :9

• Sequence 1: NP_996469.1
• Gene: Lcch3 / 32554
• FlyBaseID: FBgn0010240
• Length: 496
• Species: Drosophila melanogaster
• Sequence 2: XP_311409.4
• Gene: AgaP_AGAP010694 / 1272496
• VectorBaseID: AGAP010694
• Length: 451
• Species: Anopheles gambiae
• Alignment Length: 495
• Identity: 140/495 - (28%)
• Similarity: 229/495 - (46%)
• Gaps: 78/495 - (15%)

  Fly    26 RC-IRKDVLAGRLENVTQTISNIL-QGYDIRLR-PNFGGEPLHVGMDLTIASFDAISEVNMDYTI 87
            || :.|:|:|.:  |.|.....:| :.|...:| |:..|.|:.|...:.:...::|:..:||:.:
Mosquito     9 RCSLLKEVVAAK--NYTLKPRVVLPEDYVKEVRPPSQKGSPVVVEFSIFVVDINSINVEDMDFRV 71

  Fly    88 TMYLNQYWRDERLAFNIFGQYFDDENDDGISDVLTLSGDFAEKIWVPDTFFANDKNSFLHDVTER 152
            .|:::|.|.:.||..:      ||..::| .|.:.|..:|.:.:|.||.:|.|.|.|.:..:|.:
Mosquito    72 DMFVHQKWVESRLDLH------DDIFEEG-DDHVILPPEFFDNLWQPDPYFLNSKISEIATLTHK 129

  Fly   153 NKLVRLGGDGAVTYGMRFTTTLACMMDLHYYPLDSQNCTVEIESYGYTVSDVVMYWKPTPVRGVE 217
            ...|.|..:..|.|.......:||.|:...||:|.|.|.:.|||:.|....:.:.|....|....
Mosquito   130 FSSVTLYKNSTVRYACMMHAIIACQMEFQLYPMDIQICPIYIESFSYHNQKIRLKWADNGVTINP 194

  Fly   218 DAELPQFTI---IGYETNDRKERLATGVYQRLSLSFKLQRNIGYFVFQTYLPSILIVMLSWVSFW 279
            :.:|.|:.:   :..|..|.......|.:.||::.|:.:|.||:.:.||:.||.|:|||||.|||
Mosquito   195 ELKLLQYNLGQPLQLEETDGYMPEKYGNFSRLAVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFW 259

  Fly   280 INHEATSARVALGITTVLTMTTISTGVRSSLPRISYVKAIDIYLVMCFVFVFAALLEYAA----- 339
            :..:|...||.|.:|.:||:.|:.||:|:.:|.::||||:|:::..|.:|||:||.|:..
Mosquito   260 LGLDAIPGRVTLLVTCMLTLVTMFTGMRADIPPVAYVKALDLWMAGCMLFVFSALGEFVVVKVLD 324

  Fly   340 VNYTYWGKRAKKKIKKVKECCPGKIGKSERSETCSTTEDIIELQDVRMSPIPSLRRGTYNATLDS 404
            |.|.|       ::.||.:..|.:|...|:.: |..|....|...|.:.|    |:.|...|...
Mosquito   325 VQYQY-------QVNKVPKVLPMRISAMEKGQ-CVGTVANWEGGTVNVRP----RKPTQTPTTPG 377

  Fly   405 IGTETMNLG---KFPPSFRITRNYG----------TGHSQLRRRAQRGISTRPRMLHALKRGASA 456
            ..:...|.|   ..||:.:.||...          ||..::..|.
Mosquito   378 QVSLQGNGGPQPPLPPTKQPTRRQSILSVAWTDTDTGIEKIMWRE-------------------- 422

  Fly   457 IKATIPKIKDVNIIDKYSRMIFPISFLAFNLGYWLFYILE 496
                         |||.||::||..||.|.:.||...|.:
Mosquito   423 -------------IDKMSRVVFPGLFLVFVVLYWPILIFK 449

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Lcch3	NP_996469.1	LIC	15..493	CDD:273305	139/490 (28%)
		Neur_chan_LBD	47..256	CDD:280998	56/213 (26%)
		Neur_chan_memb	263..490	CDD:280999	71/244 (29%)
AgaP_AGAP010694	XP_311409.4	Neur_chan_LBD	32..236	CDD:280998	55/210 (26%)
		LIC	33..443	CDD:273305	129/461 (28%)
		Neur_chan_memb	243..443	CDD:280999	71/244 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810