DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Lcch3 and AgaP_AGAP012975

DIOPT Version :9

Sequence 1:	NP_996469.1	Gene:	Lcch3 / 32554	FlyBaseID:	FBgn0010240	Length:	496	Species:	Drosophila melanogaster
Sequence 2:	XP_003436941.1	Gene:	AgaP_AGAP012975 / 11175937	VectorBaseID:	AGAP012975	Length:	210	Species:	Anopheles gambiae

Alignment Length:	195	Identity:	63/195 - (32%)
Similarity:	93/195 - (47%)	Gaps:	22/195 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    43 TISNIL----QGYDIRLRPNFGGEPLHVGMDLTIASFDAISEVNMDYTITMYLNQYWRDERLAF- 102
            ::|:||    :.||....|...|:|..|...:|:.|.|:|:|.:|.|...::|.|.|||.||..
Mosquito    17 SLSDILPTHQKTYDKNRAPKLLGQPTVVYFHVTVLSIDSINEESMTYVADIFLAQSWRDPRLRLP 81

  Fly   103 -NIFGQYFDDENDDGISDVLTLSGDFAEKIWVPDTFFANDKNSFLHDVTERNKLVRLGGDGAVTY 166
             |:..:|       .|.||     |:...||.||.||.|.|....|:::..|..:.|..|..:.|
Mosquito    82 ENMSEEY-------RILDV-----DWLHSIWRPDCFFKNAKKVTFHEMSIPNHYLWLYHDKTLLY 134

  Fly   167 GMRFTTTLACMMDLHYYPLDSQNCTVEIES--YG-YTVSDVVMYWKPTPVRGVEDAELPQFTIIG 228
            ..:.|..|:|.|....||.|:|.|::.|||  || |......:.||....:.:.: |||:....|
Mosquito   135 MSKLTLVLSCAMKFESYPHDTQICSMMIESCKYGQYQGKGCRVVWKKLQRKKLAE-ELPEVWFFG 198

Fly 229 228
Mosquito 199 198

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Lcch3	NP_996469.1	LIC	15..493	CDD:273305	63/195 (32%)
		Neur_chan_LBD	47..256	CDD:280998	62/191 (32%)
		Neur_chan_memb	263..490	CDD:280999
AgaP_AGAP012975	XP_003436941.1	Neur_chan_LBD	29..208	CDD:280998	60/183 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810