Protein Alignment Lcch3 and Gabra5

DIOPT Version :9

• Sequence 1: NP_996469.1
• Gene: Lcch3 / 32554
• FlyBaseID: FBgn0010240
• Length: 496
• Species: Drosophila melanogaster
• Sequence 2: NP_001349090.1
• Gene: Gabra5 / 110886
• MGIID: 95617
• Length: 463
• Species: Mus musculus
• Alignment Length: 469
• Identity: 168/469 - (35%)
• Similarity: 234/469 - (49%)
• Gaps: 83/469 - (17%)

  Fly    41 TQTISNILQGYDIRLRPNFGGEPLHVGMDLTIASFDAISEVNMDYTITMYLNQYWRDERLAFNIF 105
            |:.:..:|.|||.||||..|.....|..|:.:.||..:|:..|:|||.::..|.|:||||.|.
Mouse    50 TRILDGLLDGYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQSWKDERLRFK-- 112

  Fly   106 GQYFDDENDDGISDVLTLSGDFAEKIWVPDTFFANDKNSFLHDVTERNKLVRLGGDGAVTYGMRF 170
                      |....|.|:...|.|||.|||||.|.|.|..|::|..|||:||..||.:.|.||.
Mouse   113 ----------GPMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLYTMRL 167

  Fly   171 TTTLACMMDLHYYPLDSQNCTVEIESYGYTVSDVVMYWKPTPVRGVEDAE----LPQFTIIGYET 231
            |.:..|.|.|..:|:|:..|.::..||.|..|:||..|.....:.|..||    |.|:.::|...
Mouse   168 TISAECPMQLEDFPMDAHACPLKFGSYAYPNSEVVYVWTNGSTKSVVVAEDGSRLNQYHLMGQTV 232

  Fly   232 NDRKERLATGVYQRLSLSFKLQRNIGYFVFQTYLPSILIVMLSWVSFWINHEATSARVALGITTV 296
            .......:||.|..::..|.|:|.|||||.|||||.|:.|:||.||||:|.|:..||...|:|||
Mouse   233 GTENISTSTGEYTIMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTV 297

  Fly   297 LTMTTISTGVRSSLPRISYVKAIDIYLVMCFVFVFAALLEYAAVNY---TYWGKRAKKKIKKVKE 358
            |||||:|...|:|||:::|..|:|.::.:|:.|||:||:|:|.|||   ..|....||.::
Mouse   298 LTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGWAWDGKKALE---- 358

  Fly   359 CCPGKIGKSERSETCSTTEDIIELQDVRMSPIPSLRRGTYNATLDSIGTETMNLGK-FPPSFRIT 422
              ..||.|.||        ::|            |.:.| ||......|...|:.| .||:
Mouse   359 --AAKIKKKER--------ELI------------LNKST-NAFTTGKLTHPPNIPKEQPPA---- 396

  Fly   423 RNYGTGHSQLRRRAQRGISTRPRMLHALKRGASAIKATIPKIKD-------VNIIDKYSRMIFPI 480
                            |.:..|.:         :|||:..|..:       ::.|||.||::|||
Mouse   397 ----------------GTANAPTV---------SIKASEEKTAESKKTYNSISKIDKMSRIVFPI 436

  Fly   481 SFLAFNLGYWLFYI 494
            .|..|||.||..|:
Mouse   437 LFGTFNLVYWATYL 450

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Lcch3	NP_996469.1	LIC	15..493	CDD:273305	167/466 (36%)
		Neur_chan_LBD	47..256	CDD:280998	78/212 (37%)
		Neur_chan_memb	263..490	CDD:280999	80/237 (34%)
Gabra5	NP_001349090.1	LIC	15..449	CDD:273305	167/466 (36%)
		LGIC_ECD_GABAAR_A5	58..256	CDD:349839	76/209 (36%)
		Cys-loop	173..187	CDD:349839	5/13 (38%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	387..408		7/49 (14%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810