Protein Alignment Lcch3 and gabra2a

DIOPT Version :9

• Sequence 1: NP_996469.1
• Gene: Lcch3 / 32554
• FlyBaseID: FBgn0010240
• Length: 496
• Species: Drosophila melanogaster
• Sequence 2: XP_009305482.1
• Gene: gabra2a / 100150704
• ZFINID: ZDB-GENE-141216-16
• Length: 451
• Species: Danio rerio
• Alignment Length: 501
• Identity: 165/501 - (32%)
• Similarity: 240/501 - (47%)
• Gaps: 78/501 - (15%)

  Fly     6 RVGVSCG----LFFFLLGAQLQLIRCIRKDVLAGRLENVTQTISNILQGYDIRLRPNFGGEPLHV 66
            |.|.|.|    ||..:|............|.....:...|:.:..:|.|||.||||..|.....|
Zfish     4 RRGHSHGFLIHLFLLVLWRACSEAEVSGSDAFKNNITLFTRILDRLLDGYDNRLRPGLGDRVTEV 68

  Fly    67 GMDLTIASFDAISEVNMDYTITMYLNQYWRDERLAFNIFGQYFDDENDDGISDVLTLSGDFAEKI 131
            ..|:.:.||..:|:.:|:||:.::..|.|.||||.|:            |..::|.|:...|.||
Zfish    69 KTDIYVTSFGPVSDTDMEYTVDVFFRQRWTDERLKFH------------GPMNILRLNNLMASKI 121

  Fly   132 WVPDTFFANDKNSFLHDVTERNKLVRLGGDGAVTYGMRFTTTLACMMDLHYYPLDSQNCTVEIES 196
            |.|||||.|.|.|..|::|..|||:|:..:|.:.|.||.|....|.|.|..:|:|..:|.::..|
Zfish   122 WTPDTFFHNGKKSVAHNMTMPNKLLRIMENGTLLYTMRLTVQAECPMHLEDFPMDFHSCPLKFGS 186

  Fly   197 YGYTVSDVVMYWKPTPVRGVEDA----ELPQFTIIGYETNDRKERLATGVYQRLSLSFKLQRNIG 257
            |.||:::|...|.......||.|    .|.|:.::|........:.:||.|..::..|.|:|.||
Zfish   187 YAYTLTEVTYVWTRNATLSVEVAPDGSRLNQYDLMGQTVGKETIKSSTGEYTVMTAHFHLKRKIG 251

  Fly   258 YFVFQTYLPSILIVMLSWVSFWINHEATSARVALGITTVLTMTTISTGVRSSLPRISYVKAIDIY 322
            |||.|||||.|:.|:||.||||:|.|:..||...|:||||||||:|...|:|||:::|..|:|.:
Zfish   252 YFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWF 316

  Fly   323 LVMCFVFVFAALLEYAAVNY---TYWGKRAKKKIK-KVKECCPGKIGKSERSETCSTTEDIIELQ 383
            :.:|:.|||:||:|:|.|||   ..|....|..:. |.||....|...:......:....|
Zfish   317 IAVCYAFVFSALIEFATVNYFTKRGWAWDGKSIVNDKKKETSVMKKNNAYAVAVANYAPHI---- 377

  Fly   384 DVRMSPIPSLRRGTYNATLDSIGTETMNLGKFPPSFRITRNYGTGHSQLRRRAQRGISTRPRMLH 448
             .:.|.:|::.:   :||.:             ||                :||
Zfish   378 -AKDSALPTVSK---SATPE-------------PS----------------KAQ----------- 398

  Fly   449 ALKRGASAIKATIPKIKDVNIIDKYSRMIFPISFLAFNLGYWLFYI 494
                  ...|.|......|:.||:.||:|||:.|.:|||.||..|:
Zfish   399 ------PVAKETKKTFNSVSKIDRMSRIIFPVLFGSFNLVYWATYL 438

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Lcch3	NP_996469.1	LIC	15..493	CDD:273305	158/485 (33%)
		Neur_chan_LBD	47..256	CDD:280998	74/212 (35%)
		Neur_chan_memb	263..490	CDD:280999	73/230 (32%)
gabra2a	XP_009305482.1	LIC	17..437	CDD:273305	158/485 (33%)
		Neur_chan_LBD	43..250	CDD:280998	75/218 (34%)
		Neur_chan_memb	257..434	CDD:280999	73/230 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810