Protein Alignment Lcch3 and gabrb2

DIOPT Version :9

• Sequence 1: NP_996469.1
• Gene: Lcch3 / 32554
• FlyBaseID: FBgn0010240
• Length: 496
• Species: Drosophila melanogaster
• Sequence 2: NP_001096421.1
• Gene: gabrb2 / 100125027
• XenbaseID: XB-GENE-5791411
• Length: 474
• Species: Xenopus tropicalis
• Alignment Length: 466
• Identity: 235/466 - (50%)
• Similarity: 308/466 - (66%)
• Gaps: 39/466 - (8%)

  Fly    40 VTQTISNILQGYDIRLRPNFGGEPLHVGMDLTIASFDAISEVNMDYTITMYLNQYWRDERLAFNI 104
            |.:|:..:|:||||||||:|||:|:.|||::.|||.|.:||||||||:|||..|.|||:||::::
 Frog    36 VKETVDRLLKGYDIRLRPDFGGDPVAVGMNIDIASIDMVSEVNMDYTLTMYFQQAWRDKRLSYSV 100

  Fly   105 FGQYFDDENDDGISDVLTLSGDFAEKIWVPDTFFANDKNSFLHDVTERNKLVRLGGDGAVTYGMR 169
                        |...|||....|:::|||||:|.|||.||:|.||.:|:::||..||.|.||:|
 Frog   101 ------------IPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLR 153

  Fly   170 FTTTLACMMDLHYYPLDSQNCTVEIESYGYTVSDVVMYWK--PTPVRGVEDAELPQFTIIGYETN 232
            .|||.||||||..||||.||||:||||||||..|:..||:  ...|.|||..|||||:||.|...
 Frog   154 ITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIGFYWRGGNNAVTGVERLELPQFSIIDYNLL 218

  Fly   233 DRKERLATGVYQRLSLSFKLQRNIGYFVFQTYLPSILIVMLSWVSFWINHEATSARVALGITTVL 297
            .|....:||.|.||||||||:||||||:.|||:|||||.:|||||||||::|::|||||||||||
 Frog   219 SRNVVFSTGSYPRLSLSFKLRRNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVL 283

  Fly   298 TMTTISTGVRSSLPRISYVKAIDIYLVMCFVFVFAALLEYAAVNYTYWGKRAKKKIKKVKECCPG 362
            |||||:|.:|.:||:|.||||||:||:.||||||.||||||.|||.::| |..::.|:.
 Frog   284 TMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFMALLEYALVNYIFFG-RGPQRQKRA------ 341

  Fly   363 KIGKSERSETCSTTEDIIELQDVRMSPIPSLRRGTYNATLDSIGTE-TMNLGKFPPSFRITRNYG 426
                :||:...:..:..:||.  :|.|..::...|.....:...:| .|.||. |.|..:.  |.
 Frog   342 ----AERAAHANNEQMRMELN--KMDPHENILLSTLEIKNEMAASEAVMGLGD-PRSTMLA--YD 397

  Fly   427 TGHSQLRR----RAQRGISTRPRML----HALKRGASAIKATIPKIKDVNIIDKYSRMIFPISFL 483
            |...|.|:    |...|.:...|.:    ..|:|.||.:|..||.:.|||.||::||||||:.|.
 Frog   398 TSSIQYRKAGLPRHSYGRNALERHVVQKKSRLRRRASQLKINIPDLTDVNAIDRWSRMIFPVVFS 462

  Fly   484 AFNLGYWLFYI 494
            .||:.|||:|:
 Frog   463 FFNIVYWLYYV 473

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Lcch3	NP_996469.1	LIC	15..493	CDD:273305	234/463 (51%)
		Neur_chan_LBD	47..256	CDD:280998	118/210 (56%)
		Neur_chan_memb	263..490	CDD:280999	105/235 (45%)
gabrb2	NP_001096421.1	LIC	13..472	CDD:273305	234/463 (51%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	246	1.000	Domainoid score	I2127
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	439	1.000	Inparanoid score	I1627
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D226476at33208
OrthoFinder	1	1.000	-	-		FOG0001081
OrthoInspector	1	1.000	-	-		otm48038
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2537
SonicParanoid	1	1.000	-	-		X650
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	7.090