Protein Alignment CG8916 and Gabrg3

DIOPT Version :10

• Sequence 1: NP_573090.3
• Gene: CG8916 / 32553
• FlyBaseID: FBgn0030707
• Length: 612
• Species: Drosophila melanogaster
• Sequence 2: NP_077346.3
• Gene: Gabrg3 / 79211
• RGDID: 621735
• Length: 467
• Species: Rattus norvegicus
• Alignment Length: 531
• Identity: 163/531 - (30%)
• Similarity: 245/531 - (46%)
• Gaps: 110/531 - (20%)

  Fly    85 SSSEISNQRRVRRKAAADMLSRNISMILENLLKRYEQSQLPTHGQGVPTVVQTNILIRSMGPVSE 149
            |....|||:.|....:.|   .::::||..||:.|::...|..|. .|||:..:|.:.|:||||.
  Rat    27 SEDSPSNQKWVLAPKSQD---TDVTLILNKLLREYDKKLRPDIGI-KPTVIDVDIYVNSIGPVSS 87

  Fly   150 LDMDYSMDCYFRQYWRDKRLSFKGPIKSLSLSIKMLDKIWRPDTYFYNGKHSQIHMITVPNKLLR 214
            ::|:|.:|.:|.|.|.|.||.|...:|.|:|:..|:..||.|||.|.|.|.::.|.||.||:|||
  Rat    88 INMEYQIDIFFAQTWTDSRLRFNSTMKILTLNSNMVGLIWIPDTIFRNSKTAEAHWITTPNQLLR 152

  Fly   215 LDQNGGILYSMRLTIKATCPMELQNFPMDRQSCPLVIGSYGYINQQLIYEWKNQDDAVSFVPGMT 279
            :..:|.|||::||||.|.|.::|.|||||..:|||...||||..:::||.|:......:......
  Rat   153 IWNDGKILYTLRLTINAECQLQLHNFPMDAHACPLTFSSYGYPKEEMIYRWRKNSVEAADQKSWR 217

  Fly   280 LNQFDLISMMHRNFTTVRREGDFSVLHVAFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREAT 344
            |.|||.:.:.:.........||:.|:.:.|.|.|..|||.||.|:||||.||||||||||.::||
  Rat   218 LYQFDFMGLRNTTEIVTTSAGDYVVMTIYFELSRRMGYFTIQTYIPCILTVVLSWVSFWIKKDAT 282

  Fly   345 SDRVSLCVTSVLTLSTISLDSRTDLPKVKYATALDWFLLMSFLYCIATLLEFAGVHYFTKLGSGE 409
            ..|.:|.:|:|||::|:|..:|..||:|.|.||:|.|:.:.||:..|.|:|:|.::|::   |..
  Rat   283 PARTTLGITTVLTMTTLSTIARKSLPRVSYVTAMDLFVTVCFLFVFAALMEYATLNYYS---SCR 344

  Fly   410 SPQLEDQWEDICIANSLSDHAGEVDGDGEADADPFADEDSSNGSENDDNEAGASESVESKSGVCV 474
            .|.:.                                                      |....:
  Rat   345 KPTIR------------------------------------------------------KKKTSL 355

  Fly   475 CNKNDALGLEYEVSLQNSLAGAGFLKRNAIFCPTYNDPSYILPNTMERTTQTEPPAVSRLHQMWM 539
            .:.:....:...:|||                         .|:.........||.|       |
  Rat   356 LHPDSTRWIPDRISLQ-------------------------APSNYSLLDMRPPPPV-------M 388

  Fly   540 CLKSDNSFRKQRERNAAAQ----KSEQGGANCYVN-------------SVSLIDRVARIAFPMSF 587
            ...:::.:.::.|.....:    |..|....||..             .||.:|..:|:.||.||
  Rat   389 ITLNNSMYWQEFEDTCVYECLDGKDCQSFFCCYEECKSGSWRRGRIHIDVSELDSYSRVFFPTSF 453

  Fly   588 AFLNLLYWWAY 598
            ...||:||..|
  Rat   454 LLFNLVYWVGY 464

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8916	NP_573090.3	LIC	92..598	CDD:455710	159/522 (30%)
		LGIC_ECD_GABAR_GRD-like	132..314	CDD:349808	74/181 (41%)
		Cys-loop	233..247	CDD:349808	7/13 (54%)
Gabrg3	NP_077346.3	LIC	50..464	CDD:455710	156/503 (31%)
		LGIC_ECD_GABAAR_G	71..252	CDD:349801	73/180 (41%)
		Cys-loop	171..185	CDD:349801	7/13 (54%)