Protein Alignment CG8916 and gabrd

DIOPT Version :10

• Sequence 1: NP_573090.3
• Gene: CG8916 / 32553
• FlyBaseID: FBgn0030707
• Length: 612
• Species: Drosophila melanogaster
• Sequence 2: XP_700099.5
• Gene: gabrd / 571422
• ZFINID: ZDB-GENE-081105-170
• Length: 459
• Species: Danio rerio
• Alignment Length: 527
• Identity: 156/527 - (29%)
• Similarity: 246/527 - (46%)
• Gaps: 98/527 - (18%)

  Fly    89 ISNQRRVRRKAA--ADMLSRNISMI----LENLLKRYEQSQLPTHGQGVPTVVQTNILIRSMGPV 147
            |...||.|...:  .|.:..:|.:.    |::|:|.|.::..|..| |.|..|...|.:.|:..:
Zfish    16 IGGDRRSRAMLSDIGDYVGTDIEISWLPNLDDLMKGYARNFRPGIG-GPPVNVAMAIEVASIDHI 79

  Fly   148 SELDMDYSMDCYFRQYWRDKRLSFKGPIKSLSLSIKMLDKIWRPDTYFYNGKHSQIHMITVPNKL 212
            ||.:|:|:|..:.||.|||.|||:....|:|.|..:.:||:|.|||:..|.|.:..|.:||.|||
Zfish    80 SEANMEYTMTVFLRQSWRDDRLSYNHTNKTLGLDSRFVDKLWLPDTFIVNAKSAWFHDVTVENKL 144

  Fly   213 LRLDQNGGILYSMRLTIKATCPMELQNFPMDRQSCPLVIGSYGYINQQLIYEWKNQDDAVSFVPG 277
            :||..:|.||||.|:|....|.|:|..:|||.|.|.|.:.||||.::.::|.|......:..:..
Zfish   145 IRLQPDGVILYSSRITSTVACDMDLTKYPMDEQECMLDLESYGYSSEDIVYHWSESQKLIHGLDK 209

  Fly   278 MTLNQFDL------ISMMHRNFTTVRREGDFSVLHVAFNLKRHTGYFLIQVYVPCILIVVLSWVS 336
            :.|:||.:      ..||  ||   :..|.|..|.:.|.|:|:.|.::||.|:|.||:|.:||||
Zfish   210 LELSQFTITDYRFVTEMM--NF---KSAGRFPRLSLRFQLRRNRGVYIIQSYMPSILLVAMSWVS 269

  Fly   337 FWIHREATSDRVSLCVTSVLTLSTISLDSRTDLPKVKYATALDWFLLMSFLYCIATLLEFAGVHY 401
            |||.:.|...||||.:|:|||::|:.:.:|:.||:.....|||.:..:.:::..|.|:|:|..||
Zfish   270 FWISQSAVPARVSLGITTVLTMTTLMVSARSSLPRASAIKALDVYFWICYVFVFAALIEYAFAHY 334

  Fly   402 FTKLGSGESPQLEDQWEDICIANSLSDHAGEVDGDGEADADPFADEDSSNGSENDDNEAGASESV 466
                                                           :::.|:.:..:...:::.
Zfish   335 -----------------------------------------------NADYSKKEKAKVKTNKNA 352

  Fly   467 ESKSGVCVCNKNDALGLEYEVSLQNSLAGAGFLKRNAIFCPTYNDPSYILPNTMERTTQTEPPAV 531
            ||    .|.|...|:.|       .||:.||.            :...::.|...|:.:....|.
Zfish   353 ES----MVKNGKQAMVL-------FSLSVAGM------------NQGLLISNRQSRSHRASDAAA 394

  Fly   532 SRL--HQMWMCLKSDNSFRKQRERNAAAQKSEQGG-ANCYVNSVSLIDRVARIAFPMSFAFLNLL 593
            :..  |:       :...|....|.|..:.||:.. ..|.......||..||..||.:||.:|::
Zfish   395 AAADPHE-------ETETRSATSRRAQKESSEEKKCCKCKPIDADTIDIYARAVFPFTFAVVNVI 452

  Fly   594 YWWAYGM 600
            ||.||.|
Zfish   453 YWVAYTM 459

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8916	NP_573090.3	LIC	92..598	CDD:455710	152/520 (29%)
		LGIC_ECD_GABAR_GRD-like	132..314	CDD:349808	70/187 (37%)
		Cys-loop	233..247	CDD:349808	7/13 (54%)
gabrd	XP_700099.5	LIC	45..457	CDD:455710	147/494 (30%)
		LGIC_ECD	64..247	CDD:475126	70/187 (37%)