Protein Alignment CG8916 and gabrb3

DIOPT Version :10

• Sequence 1: NP_573090.3
• Gene: CG8916 / 32553
• FlyBaseID: FBgn0030707
• Length: 612
• Species: Drosophila melanogaster
• Sequence 2: XP_021327485.1
• Gene: gabrb3 / 566922
• ZFINID: ZDB-GENE-101102-2
• Length: 532
• Species: Danio rerio
• Alignment Length: 532
• Identity: 172/532 - (32%)
• Similarity: 272/532 - (51%)
• Gaps: 108/532 - (20%)

  Fly   107 NISMI---LENLLKRYEQSQLPTHGQGVPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDKR 168
            |:|.:   ::.|||.|:....|..| |.|..|..:|.:.|:..|||::|||::..||:|||||||
Zfish    67 NMSFVKETVDKLLKGYDIRLRPDFG-GAPVAVGMSIDVASIDMVSEVNMDYTLTMYFQQYWRDKR 130

  Fly   169 LSFKGPIKSLSLSIKMLDKIWRPDTYFYNGKHSQIHMITVPNKLLRLDQNGGILYSMRLTIKATC 233
            |::.|...:|:|..::.|::|.|||||.|.|.|.:|.:||.|:::||..:|.:||.:|:|..|.|
Zfish   131 LAYTGIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAAC 195

  Fly   234 PMELQNFPMDRQSCPLVIGSYGYINQQLIYEWKNQDDAVSFVPGMTLNQFDLI--SMMHRN--FT 294
            .|:|:.:|:|.|:|.|.|.||||....:.:.||..:.||:.|..:.|.||.::  .::.||  |:
Zfish   196 MMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWKGGETAVTGVSRIELPQFSIVDYKLVSRNVVFS 260

  Fly   295 TVRREGDFSVLHVAFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREATSDRVSLCVTSVLTLS 359
            |    |.:..|.::|.|||:.|||::|.|:|.|||.:||||||||:.:|::.||:|.:|:|||::
Zfish   261 T----GAYPRLSLSFKLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMT 321

  Fly   360 TISLDSRTDLPKVKYATALDWFLLMSFLYCIATLLEFAGVHYFTKLGSGESPQLEDQWEDICIAN 424
            ||:...|..|||:.|..|:|.:|:..|::....|||:|.|:|   :..|..||::         .
Zfish   322 TINTHLRETLPKIPYVKAIDMYLMGCFVFVFLALLEYAFVNY---IFFGRGPQMQ---------K 374

  Fly   425 SLSDHAGEVDGDGEADADPFADEDSSNGSENDDNEAGASESVESKSGVC----VCNKNDALGLEY 485
            .|::.|.:                    :.||.|:...::||: :.|.|    |...|...|..:
Zfish   375 KLAEKAEK--------------------ANNDRNKYDGNKSVQ-EGGNCKPSSVKQSNQVQGHRH 418

  Fly   486 E-------------VSLQNSLAGAGFLKRNAIFCPTYNDPSYILPNTMERTTQTEPPAVSRLHQM 537
            .             :.:.|.:||                 :.|..:..|....|.
Zfish   419 SRGVDSQGNILLTTLEIHNEVAG-----------------NEITTSVSEARNSTS---------- 456

  Fly   538 WMCLKSDNS---FRKQ------RERNAAAQKSEQGGANCY-------VNSVSLIDRVARIAFPMS 586
               :..|||   :|||      .:|||.::|......:..       :..|:.|||.:||.||..
Zfish   457 ---MVFDNSGIQYRKQSTARHSMDRNAQSKKPRLRRRSSQLKIKIPDLTDVNAIDRWSRIIFPAV 518

  Fly   587 FAFLNLLYWWAY 598
            |:..||:||..|
Zfish   519 FSLFNLIYWLYY 530

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8916	NP_573090.3	LIC	92..598	CDD:455710	171/530 (32%)
		LGIC_ECD_GABAR_GRD-like	132..314	CDD:349808	75/185 (41%)
		Cys-loop	233..247	CDD:349808	6/13 (46%)
gabrb3	XP_021327485.1	LIC	61..530	CDD:273305	171/530 (32%)