DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG8916 and glrbb

DIOPT Version :9

Sequence 1:NP_573090.3 Gene:CG8916 / 32553 FlyBaseID:FBgn0030707 Length:612 Species:Drosophila melanogaster
Sequence 2:XP_021336678.1 Gene:glrbb / 445193 ZFINID:ZDB-GENE-040801-106 Length:502 Species:Danio rerio


Alignment Length:542 Identity:155/542 - (28%)
Similarity:251/542 - (46%) Gaps:89/542 - (16%)


- Green bases have known domain annotations that are detailed below.


  Fly    72 SLKRSQNATNLSYSSSEISNQRRVRRKAAADMLSRNISMILENLLKRYEQSQLPTHGQGVPTVVQ 136
            |.|:.:......|..|::|::...|..|      .:.|.||..||..|:....|.. :|:|...:
Zfish    34 SAKKGKKKGKQVYCPSQLSSEDLARVPA------NSTSNILNKLLITYDPRIRPNF-KGIPVEDR 91

  Fly   137 TNILIRSMGPVSELDMDYSMDCYFRQYWRDKRLSFKGPIKSLSLSI--KMLDKIWRPDTYFYNGK 199
            .||.|.|.|.:.|..|||.::.:.||.|.|.||......||.||::  ||...:|:||.:|.|.|
Zfish    92 VNIFINSFGSIQETTMDYRVNIFLRQRWNDPRLRLPQDFKSDSLTVDPKMFKCLWKPDLFFANEK 156

  Fly   200 HSQIHMITVPNKLLRLDQNGGILYSMRLTIKATCPMELQNFPMDRQSCPLVIGSYGYINQQLIYE 264
            .:..|.:|..|.||.:.:||.:|.||||::..:||::|..||||.|.|.:.:.|:||....|.:.
Zfish   157 SANFHDVTQENILLFIFRNGDVLISMRLSVTLSCPLDLTLFPMDTQRCKMQLESFGYTTDDLQFM 221

  Fly   265 WKNQDDAVSFVPGMTLNQFDL--ISMMHRNFTT-VRREGDFSVLHVAFNLKRHTGYFLIQVYVPC 326
            |::.|...  :..:.|.|||:  ..:.:.|.|. ....|.::.:.|.|.|:|..|::::.||.|.
Zfish   222 WQSGDPVQ--MDEIALPQFDIKQEDIEYGNCTKYYAGTGYYTCVEVIFTLRRQVGFYMMGVYAPT 284

  Fly   327 ILIVVLSWVSFWIHREATSDRVSLCVTSVLTLSTISLDSRTDLPKVKYATALDWFLLMSFLYCIA 391
            :|||||||:||||:.:|::.||.|.:.|||:||:......::||||.|..|:|.:|:...|:..|
Zfish   285 LLIVVLSWLSFWINPDASAARVPLGILSVLSLSSECTSLASELPKVSYVKAIDIWLIACLLFGFA 349

  Fly   392 TLLEFAGVHYFTKLGSGESPQLEDQWEDICIANSLSDHAGEVDGDGEADADPFADEDSSNG---S 453
            :|:|:|.|....     .||:|.                       ||:....|.::.:.|   :
Zfish   350 SLVEYAVVQVML-----NSPKLL-----------------------EAERAKIATKEKAEGKTPA 386

  Fly   454 ENDDNEAGAS-------ESVESKSGVCVCNKNDALGLEYEVSLQNSLAGAGFLKRNAIFCPTYND 511
            :|..|..|::       :..|::......:|:|....::      |:.|:               
Zfish   387 KNTINGMGSTPIHVSTLQVTETRCKKVCTSKSDLRTNDF------SIVGS--------------- 430

  Fly   512 PSYILPNTMERTTQTEPPAVSRLHQMWMCLKSDNSFRKQRERNAAAQKSEQGGANCYVNSVSLID 576
                ||...|         :|........::..::|.|.:.:|   .|..........::...||
Zfish   431 ----LPRDFE---------LSNFDCYGKPIEVGSAFSKSQAKN---NKKPPPPKPVIPSAAKRID 479

  Fly   577 RVARIAFPMSFAFLNLLYWWAY 598
            ..||..||.||.|.|::||..|
Zfish   480 LYARALFPFSFLFFNVIYWSVY 501

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG8916NP_573090.3 LIC 92..598 CDD:273305 149/520 (29%)
Neur_chan_LBD 111..315 CDD:280998 73/208 (35%)
Neur_chan_memb 322..>403 CDD:280999 37/80 (46%)
glrbbXP_021336678.1 Neur_chan_LBD 53..501 CDD:332142 149/521 (29%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3644
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 1 0.960 - -
ZFIN 00.000 Not matched by this tool.
43.770

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