Protein Alignment CG8916 and pHCl-2

DIOPT Version :10

• Sequence 1: NP_573090.3
• Gene: CG8916 / 32553
• FlyBaseID: FBgn0030707
• Length: 612
• Species: Drosophila melanogaster
• Sequence 2: NP_651861.1
• Gene: pHCl-2 / 43703
• FlyBaseID: FBgn0039840
• Length: 526
• Species: Drosophila melanogaster
• Alignment Length: 554
• Identity: 139/554 - (25%)
• Similarity: 225/554 - (40%)
• Gaps: 94/554 - (16%)

  Fly    70 NGSLKRSQNATNLSYSSSEISNQRRVRRKAAADMLSRNISMILENLLK------RYEQSQLPT-- 126
            |||:..|...|..::|.|...:|..|..   ...|....||.|..||.      ||::...|.
  Fly    33 NGSVVVSPLNTTDAFSVSINLSQSTVNN---CPSLKNAESMALMELLTRLTAPCRYDRMVPPVVH 94

  Fly   127 --HGQGVPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDKRLSF-------KGPIKSLSLSI 182
              .|:.||..:.....|..|..:...|:.:::....:..:.|.||:|       :.||...|...
  Fly    95 NKDGEEVPMDIYARFYIYVMKNLDSSDLQFTVQGLLQLRYLDPRLAFSSYLPNRRQPIMGESELK 159

  Fly   183 KMLDKIWRPDTYFYNGKHSQIHMITVPNKLLRLDQNGGILYSMRLTIKATCPMELQNFPMDRQSC 247
            |||   |.|..:..|.:.|.:...:..::|..:..||.:|.|.||.....|.|..|.||.|.|.|
  Fly   160 KML---WVPHIFLTNEQASTVLGTSAKDELTSIYPNGTVLTSTRLQATLYCWMNFQKFPFDEQKC 221

  Fly   248 PLVIGSYGYINQQLIYEWKNQDDAVSFVPGMTLNQFDLISMMHRNFTTVRR---------EGDFS 303
            ...:.|:.|....:...|:. |:.|||...:.|.:::||..::.....|..         ||::|
  Fly   222 KTTLESWMYNTTLVQLHWET-DNPVSFDKQLQLTEYNLIGSLYNESIRVSNESYMSHGSLEGNYS 285

  Fly   304 VLHVAFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREATSDRVSLCVTSVLTLSTISLDSRTD 368
            ::.....|.|..||::|..::|.|:||.:||||||:..:.|..|.:|..|::|:..|:||....:
  Fly   286 IISFTVLLTREVGYYVIDYFLPSIMIVTISWVSFWLQADQTPARTTLGCTTLLSFITLSLSQENN 350

  Fly   369 LPKVKYATALD-WFLLMSFLYCIATLLEFAGVHYFTKLGSGESPQLEDQWEDICIANSLSDHAGE 432
            |.||.|.|..: |||:.: ::...:|:|||.|:  |........||:.:.....:.::...|..:
  Fly   351 LMKVSYVTMSEVWFLVCT-IFIFGSLVEFAFVN--TIWRRNNDLQLKKRTTKYIVKSTFVPHLKK 412

  Fly   433 VDGDGEADADPFADEDSSNGSENDDNEAGASESVESKSGVCVCNKNDALGLEYEVSLQNSLAGAG 497
            ....|....|......|:...:.                  .|..|:.:     ::::..:...|
  Fly   413 HRRHGYRRTDSTMSTMSTTSMDK------------------TCGPNNTV-----ITIETPIIIGG 454

  Fly   498 FLKRNAIFCPTYNDPSYILPNTMERTTQTEPPAVSRLHQMWMCLKSDNSFRKQRERNAAAQKSEQ 562
            .|.|         :.|.|..:..:.|:.:|              .||:|..|..:..|.....|
  Fly   455 SLSR---------EDSAISLDEQDETSTSE--------------SSDSSKEKPAQTFATMTPKE- 495

  Fly   563 GGANCYVNSVSL-IDRVARIAFPMSFAFLNLLYW 595
                     ||| |||..|..||:||...|.|:|
  Fly   496 ---------VSLWIDRKMRFVFPLSFIVFNALFW 520

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8916	NP_573090.3	LIC	92..598	CDD:455710	132/532 (25%)
		LGIC_ECD_GABAR_GRD-like	132..314	CDD:349808	48/197 (24%)
		Cys-loop	233..247	CDD:349808	7/13 (54%)
pHCl-2	NP_651861.1	LIC	46..522	CDD:455710	134/541 (25%)