DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG8916 and nAChRalpha2

DIOPT Version :9

Sequence 1:NP_573090.3 Gene:CG8916 / 32553 FlyBaseID:FBgn0030707 Length:612 Species:Drosophila melanogaster
Sequence 2:NP_524482.1 Gene:nAChRalpha2 / 42919 FlyBaseID:FBgn0000039 Length:576 Species:Drosophila melanogaster


Alignment Length:316 Identity:63/316 - (19%)
Similarity:146/316 - (46%) Gaps:38/316 - (12%)


- Green bases have known domain annotations that are detailed below.


  Fly   111 ILENLLKRYEQSQLPTHGQGVPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDKRLSFK--- 172
            :.::||..|.:...|........:|:..:.:..:..::..|...:.:.:....|:|.:..:.   
  Fly    48 LYDDLLSNYNRLIRPVSNNTDTVLVKLGLRLSQLIDLNLKDQILTTNVWLEHEWQDHKFKWDPSE 112

  Fly   173 -GPIKSLSLSIKMLDKIWRPDTYFYNGKHSQIHMITVPNKLLRLDQNGGILYSMRLTIKATCPME 236
             |.:..|.:.   .:.||.||...||....: :::|...|.: |...|.::::.....|::|.::
  Fly   113 YGGVTELYVP---SEHIWLPDIVLYNNADGE-YVVTTMTKAI-LHYTGKVVWTPPAIFKSSCEID 172

  Fly   237 LQNFPMDRQSCPLVIGSYGYINQQL----IYEWKNQDDAVSFVPGMTLNQF------DLISM--- 288
            ::.||.|:|:|.:..||:.|...|:    |.:..::|:.|..  |:.|.::      |::.:   
  Fly   173 VRYFPFDQQTCFMKFGSWTYDGDQIDLKHISQKNDKDNKVEI--GIDLREYYPSVEWDILGVPAE 235

  Fly   289 MHRNFTTVRREGDFSVLHVAFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREATSDRVSLCVT 353
            .|..:.....| .:..:.....|:|.|.::.:.:.:||:.|..||.:.|::..: :.::::||::
  Fly   236 RHEKYYPCCAE-PYPDIFFNITLRRKTLFYTVNLIIPCVGISYLSVLVFYLPAD-SGEKIALCIS 298

  Fly   354 SVLT-------LSTISLDSRTDLPKV-KYATALDWFLLMSFLYCIATLLEFAGVHY 401
            .:|:       :|.|...:...||.: ||   |.:.:|:..|..:.|:: ...:||
  Fly   299 ILLSQTMFFLLISEIIPSTSLALPLLGKY---LLFTMLLVGLSVVITII-ILNIHY 350

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG8916NP_573090.3 LIC 92..598 CDD:273305 63/316 (20%)
Neur_chan_LBD 111..315 CDD:280998 41/220 (19%)
Neur_chan_memb 322..>403 CDD:280999 21/88 (24%)
nAChRalpha2NP_524482.1 LGIC_ECD_nAChR_proto_alpha-like 44..263 CDD:349832 42/222 (19%)
LIC 47..544 CDD:273305 63/316 (20%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - P PTHR18945
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
11.100

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