Protein Alignment CG8916 and lgc-38

DIOPT Version :9

• Sequence 1: NP_573090.3
• Gene: CG8916 / 32553
• FlyBaseID: FBgn0030707
• Length: 612
• Species: Drosophila melanogaster
• Sequence 2: NP_001355511.1
• Gene: lgc-38 / 3565717
• WormBaseID: WBGene00017389
• Length: 479
• Species: Caenorhabditis elegans
• Alignment Length: 513
• Identity: 157/513 - (30%)
• Similarity: 235/513 - (45%)
• Gaps: 102/513 - (19%)

  Fly   104 LSRNISMILENLLKRYEQSQLPTHGQGVPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDKR 168
            |..|::.:|:.|:..:::...|.:| |.|..|.....:.::..|||:.|||::|.|.||.|:|.|
 Worm    48 LENNVTRLLDKLIASHDRRIRPNYG-GPPIEVNITAHVTTISAVSEVSMDYTLDLYLRQIWKDPR 111

  Fly   169 LSFKGPIK-SLSLSIKMLDKIWRPDTYFYNGKHSQIHMITVPNKLLRLDQNGGILYSMRLTIKAT 232
            |:::..:: ||::.|.|:..||.|||:|.|.|.|..|..|..|..||:|.:|.:|.|:|||:.|.
 Worm   112 LAWESDVEDSLTIGIDMVKTIWTPDTFFPNEKKSFFHEATSHNSFLRIDNHGNVLRSIRLTVTAN 176

  Fly   233 CPMELQNFPMDRQSCPLVIGSYGYINQQLIYEWKNQDDAVSFVPGMTLNQFDLISMMHRNFTTVR 297
            |||.|..||:|||.|.|.:.||||..:.:||.| :..:||:....:.|..|.:....|...|...
 Worm   177 CPMSLHTFPLDRQECALEVESYGYSTKDIIYHW-HGTNAVTIDENVHLAHFTIGEHKHIERTISL 240

  Fly   298 REGDFSVLHVAFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREATSDRVSLCVTSVLTLSTIS 362
            ..|::|.|...|..||:.|::|||:|.|..||||:||||||::|||...||::.||:|||::|:.
 Worm   241 STGNYSRLTAYFLFKRNIGFYLIQIYFPSSLIVVISWVSFWLNREAVQARVAIGVTTVLTMTTLM 305

  Fly   363 LDSRTDLPKVKYATALDWFLLMSFLYCIATLLEFAGVHYFTKLG---SGESP----QLEDQWEDI 420
            ..:...||||.|..:||.||.:.|....|:|||:|.:.|..|..   ...||    :.|:.:|..
 Worm   306 TSTNASLPKVSYVKSLDVFLGVCFFIVFASLLEYAAIGYLMKRNRSVPAASPVQYYETEEFFEIQ 370

  Fly   421 CIANSLSDHAGEVDGDGEADADPFADEDSSNGSENDDNEAGASESVESKSGVCVCNKNDALGLEY 485
            |       |...|.|                                   .:..|:
 Worm   371 C-------HPKFVRG-----------------------------------AINYCD--------- 384

  Fly   486 EVSLQNSLAGAGFLKRNAIFCPTYNDPSYILPNTMERTTQTEP---------PAVSRLHQMWMCL 541
                       |.|||.|....:.|.....:.|.........|         |.:|.:....:..
 Worm   385 -----------GVLKREASRKKSRNRRDSSMKNYQNNNIHHRPSDGHVDQRIPLLSMVPMPPIPF 438

  Fly   542 KSDN-SFRKQRERNAAAQKSEQGGANCYVNSVSLIDRVARIAFPMSFAFLNLLYWWAY 598
            |..| ::.|.|    .||                :|..:|.|||:.|...:::||..|
 Worm   439 KPQNGAWGKVR----PAQ----------------VDLFSRFAFPIFFVIFHIVYWTYY 476

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8916	NP_573090.3	LIC	92..598	CDD:273305	156/511 (31%)
		Neur_chan_LBD	111..315	CDD:280998	77/204 (38%)
		Neur_chan_memb	322..>403	CDD:280999	39/80 (49%)
lgc-38	NP_001355511.1	LIC	42..476	CDD:273305	156/511 (31%)
		LGIC_ECD_GABAR_RDL-like	76..257	CDD:349809	70/181 (39%)
		Cys-loop	177..191	CDD:349809	9/13 (69%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810