Protein Alignment CG8916 and nAChRalpha5

DIOPT Version :10

• Sequence 1: NP_573090.3
• Gene: CG8916 / 32553
• FlyBaseID: FBgn0030707
• Length: 612
• Species: Drosophila melanogaster
• Sequence 2: NP_001356885.1
• Gene: nAChRalpha5 / 34826
• FlyBaseID: FBgn0028875
• Length: 837
• Species: Drosophila melanogaster
• Alignment Length: 390
• Identity: 84/390 - (21%)
• Similarity: 161/390 - (41%)
• Gaps: 67/390 - (17%)

  Fly    24 VTSSDLLYIKTMGPSAILTKMPNITNEFSSRIFSSFRILPSSKPKTNGSLKRSQNATNLSYSSSE 88
            :.:|.:.:|..:|             .|::::.||           :.|...|.|:.|  .||::
  Fly   245 IAASTIAFISYLG-------------SFAAQLRSS-----------SSSSSNSSNSGN--SSSTQ 283

  Fly    89 ISNQRR----------VRRKAAADMLSRNISMILENLLKRYEQSQLPTHGQGVPTVVQTNILIRS 143
            |.|...          :...|...:...:...:|.:||..|...:.|...:..|..:...:.:..
  Fly   284 ILNGLNKHSWIFLLIYLNLSAKVCLAGYHEKRLLHDLLDPYNTLERPVLNESDPLQLSFGLTLMQ 348

  Fly   144 MGPVSELDMDYSMDCYFRQYWRDKRLSFK----GPIKSLSLSIKMLDKIWRPDTYFYNGKHSQIH 204
            :..|.|.:.....:.:.:..|.|..|.:.    |.:|.|.:.   ..:||:||...||.......
  Fly   349 IIDVDEKNQLLVTNVWLKLEWNDMNLRWNTSDYGGVKDLRIP---PHRIWKPDVLMYNSADEGFD 410

  Fly   205 MITVPNKLLRLDQNGGILYSMRLTIKATCPMELQNFPMDRQSCPLVIGSYGYINQQLIYEWKNQD 269
            .....|.::|  .||..||......|:||.:::..||.|.|.|.:..||:.|...||  :.:.||
  Fly   411 GTYQTNVVVR--NNGSCLYVPPGIFKSTCKIDITWFPFDDQRCEMKFGSWTYDGFQL--DLQLQD 471

  Fly   270 DAVSFVPGMTLN-QFDLISMMHRNFTTVRREGDFSV-------LHVAFNLKRHTGYFLIQVYVPC 326
            :....:....|| :::|:.:..:     |.|..::.       :..|..::|.|.|:...:.:||
  Fly   472 ETGGDISSYVLNGEWELLGVPGK-----RNEIYYNCCPEPYIDITFAIIIRRRTLYYFFNLIIPC 531

  Fly   327 ILIVVLSWVSFWIHREATSDRVSLCVTSVLTLSTISLDSRTD-LPKVKYATALDWFLLMSFLYCI 390
            :||..::.:.|.:..: :.:::||.||.:|:| |:.|:...: :|....|..    ||.::..||
  Fly   532 VLIASMALLGFTLPPD-SGEKLSLGVTILLSL-TVFLNMVAETMPATSDAVP----LLGTYFNCI 590

  Fly   391  390
              Fly   591  590

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8916	NP_573090.3	LIC	92..598	CDD:455710	70/322 (22%)
		LGIC_ECD_GABAR_GRD-like	132..314	CDD:349808	42/193 (22%)
		Cys-loop	233..247	CDD:349808	5/13 (38%)
nAChRalpha5	NP_001356885.1	LIC	313..802	CDD:455710	69/296 (23%)