Protein Alignment CG8916 and Gabra6

DIOPT Version :9

• Sequence 1: NP_573090.3
• Gene: CG8916 / 32553
• FlyBaseID: FBgn0030707
• Length: 612
• Species: Drosophila melanogaster
• Sequence 2: NP_068613.1
• Gene: Gabra6 / 29708
• RGDID: 61861
• Length: 453
• Species: Rattus norvegicus
• Alignment Length: 501
• Identity: 183/501 - (36%)
• Similarity: 254/501 - (50%)
• Gaps: 96/501 - (19%)

  Fly   105 SRNISMILENLLKRYEQSQLPTHGQGVPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDKRL 169
            |.|:|.||:|||:.|:....|..| |..|.|:|:|.:.|.||||:::|:|:||.:|||.|.|:||
  Rat    29 SENVSRILDNLLEGYDNRLRPGFG-GAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDERL 92

  Fly   170 SFKGPIKSLSLSIKMLDKIWRPDTYFYNGKHSQIHMITVPNKLLRLDQNGGILYSMRLTIKATCP 234
            .||||.:.|||:..|:.|||.|||:|.|||.|..|.:|.||||.||..||.|||:|||||.|.||
  Rat    93 KFKGPAEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRLMHNGTILYTMRLTINADCP 157

  Fly   235 MELQNFPMDRQSCPLVIGSYGYINQQLIYEWKNQDDAVSFVP--GMTLNQFDLISMMHRNFTTVR 297
            |.|.|||||..:|||..|||.|...::||.||........||  ..:|.|:|||.....:.|...
  Rat   158 MRLVNFPMDGHACPLKFGSYAYPKSEIIYTWKKGPLYSVEVPEESSSLLQYDLIGQTVSSETIKS 222

  Fly   298 REGDFSVLHVAFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREATSDRVSLCVTSVLTLSTIS 362
            ..|::.::.|.|:|:|..|||:||:|.|||:.|:||.|||||::|:...|....:|:|||::|:|
  Rat   223 NTGEYVIMTVYFHLQRKMGYFMIQIYTPCIMTVILSQVSFWINKESVPARTVFGITTVLTMTTLS 287

  Fly   363 LDSRTDLPKVKYATALDWFLLMSFLYCIATLLEFAGVHYFTKLGSGESPQLEDQWEDICIANSLS 427
            :.:|..||||.||||:|||:.:.|.:..:.|:|||.|:|||.|   :|.:.|.|
  Rat   288 ISARHSLPKVSYATAMDWFIAVCFAFVFSALIEFAAVNYFTNL---QSQKAERQ----------- 338

  Fly   428 DHAGEVDGDGEADADPFADEDSSNGSENDDNEAGASESVESKSGVCVCNKNDALGLEYEVS---- 488
                     .:..|.|               ....|::.||.....|.:.:....|:..:|
  Rat   339 ---------AQTAAKP---------------PVAKSKTTESLEAEIVVHSDSKYHLKKRISSLTL 379

  Fly   489 -LQNSLAGAGFLKRNAIFCPTYNDPSYILPNTMERTTQTEPPAVSRLHQMWMCLKSDNSFRKQRE 552
             :..|...:..|.|..|...|...|..:||
  Rat   380 PIVPSSEASKVLSRTPILPSTPVTPPLLLP----------------------------------- 409

  Fly   553 RNAAAQKSEQGGANCYVNSVSLIDRVARIAFPMSFAFLNLLYWWAY 598
                           .:...|.||:.:||.||::||..||:||..|
  Rat   410 ---------------AIGGTSKIDQYSRILFPVAFAGFNLVYWIVY 440

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8916	NP_573090.3	LIC	92..598	CDD:273305	182/499 (36%)
		Neur_chan_LBD	111..315	CDD:280998	100/205 (49%)
		Neur_chan_memb	322..>403	CDD:280999	39/80 (49%)
Gabra6	NP_068613.1	Neur_chan_LBD	33..240	CDD:280998	101/207 (49%)
		LIC	34..440	CDD:273305	179/494 (36%)
		Neur_chan_memb	247..437	CDD:280999	72/277 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	199	1.000	Domainoid score	I2964
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H20220
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1057372at2759
OrthoFinder	1	1.000	-	-		FOG0000415
OrthoInspector	1	1.000	-	-		otm45994
orthoMCL	1	0.900	-	-		OOG6_105663
Panther	1	1.100	-	-	O	PTHR18945
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X127
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	11	10.820