Protein Alignment CG8916 and Gabrr1

DIOPT Version :10

• Sequence 1: NP_573090.3
• Gene: CG8916 / 32553
• FlyBaseID: FBgn0030707
• Length: 612
• Species: Drosophila melanogaster
• Sequence 2: NP_058987.3
• Gene: Gabrr1 / 29694
• RGDID: 61900
• Length: 480
• Species: Rattus norvegicus
• Alignment Length: 534
• Identity: 160/534 - (29%)
• Similarity: 252/534 - (47%)
• Gaps: 118/534 - (22%)

  Fly    86 SSEISNQRRVRR-------KAAADMLSRNISMILENLLKRYEQSQLPTH------GQGVPTV-VQ 136
            |.:.|..:|.||       |..:.:|.|:..:....|.|..:..::..|      |.|.|.: |.
  Rat    37 SKKGSRPQRQRRGAHDDAHKQGSPILKRSSDITKSPLTKSEQLLRIDDHDFSMRPGFGGPAIPVG 101

  Fly   137 TNILIRSMGPVSELDMDYSMDCYFRQYWRDKRLSFKGPIKSLSLSI--KMLDKIWRPDTYFYNGK 199
            .::.:.|:..:||:|||::|..|.|.||:|:||||.. ..:||::.  :::.|||.||.:|.:.|
  Rat   102 VDVQVESLDSISEVDMDFTMTLYLRHYWKDERLSFPS-TNNLSMTFDGRLVKKIWVPDMFFVHSK 165

  Fly   200 HSQIHMITVPNKLLRLDQNGGILYSMRLTIKATCPMELQNFPMDRQSCPLVIGSYGYINQQLIYE 264
            .|.||..|..|.:||:..:|.:|||:|:|:.|.|.|:...||:|.|:|.|.|.||.|....|:..
  Rat   166 RSFIHDTTTDNVMLRVQPDGKVLYSLRVTVTAMCNMDFSRFPLDTQTCSLEIESYAYTEDDLMLY 230

  Fly   265 WKNQDDAVSFVPGMTLNQFDLISMMHRNFTTVR-----REGDFSVLHVAFNLKRHTGYFLIQVYV 324
            ||..:|::.....::|:|| ||...|   ||.:     ..|.::.|::.|.|:||..:||:|.|.
  Rat   231 WKKGNDSLKTDERISLSQF-LIQEFH---TTTKLAFYSSTGWYNRLYINFTLRRHIFFFLLQTYF 291

  Fly   325 PCILIVVLSWVSFWIHREATSDRVSLCVTSVLTLSTISLDSRTDLPKVKYATALDWFLLMSFLYC 389
            |..|:|:||||||||.|.|...||.|.:|:|||:|||.......:|:|.|..|:|.:|.:||::.
  Rat   292 PATLMVMLSWVSFWIDRRAVPARVPLGITTVLTMSTIITGVNASMPRVSYIKAVDIYLWVSFVFV 356

  Fly   390 IATLLEFAGVHYFTKLGSGESPQLEDQWEDICIANSLSDHAGEVDGDGEADADPFADEDSSNGSE 454
            ..::||:|.|:|.|.:...:..:|.::....|   .|....|.:           .|...|:|..
  Rat   357 FLSVLEYAAVNYLTTVQERKERKLREKISCTC---GLPQPRGVM-----------LDSSYSDGEV 407

  Fly   455 NDDNEAGASESVESKSGVCVCNKNDALGLEYEVSLQNSLAGAGFLKRNAIFCPTYNDPSYILPNT 519
            ||                        ||              |::..|.
  Rat   408 ND------------------------LG--------------GYMPENG---------------- 418

  Fly   520 MERTTQTEPPAVSRLHQMWMCLKSDNSFRKQRERNAAAQKSEQGGANCYVN---SVSLIDRVARI 581
                   |.|  .|: .:.:.|.|        ||.:..:||::|.   ||:   :...||:.:||
  Rat   419 -------EKP--DRM-MVQLTLAS--------ERGSPQRKSQRGS---YVSMRINTHAIDKYSRI 462

  Fly   582 AFPMSFAFLNLLYW 595
            .||.::...||:||
  Rat   463 IFPAAYILFNLIYW 476

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8916	NP_573090.3	LIC	92..598	CDD:455710	158/528 (30%)
		LGIC_ECD_GABAR_GRD-like	132..314	CDD:349808	69/189 (37%)
		Cys-loop	233..247	CDD:349808	6/13 (46%)
Gabrr1	NP_058987.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	31..67		8/29 (28%)
		LIC	76..479	CDD:455710	150/495 (30%)
		LGIC_ECD_GABAAR_rho	97..282	CDD:349806	69/189 (37%)
		Cys-loop	199..213	CDD:349806	6/13 (46%)