Protein Alignment CG8916 and Gabra2

DIOPT Version :10

• Sequence 1: NP_573090.3
• Gene: CG8916 / 32553
• FlyBaseID: FBgn0030707
• Length: 612
• Species: Drosophila melanogaster
• Sequence 2: XP_017454595.1
• Gene: Gabra2 / 289606
• RGDID: 61856
• Length: 504
• Species: Rattus norvegicus
• Alignment Length: 512
• Identity: 188/512 - (36%)
• Similarity: 263/512 - (51%)
• Gaps: 101/512 - (19%)

  Fly    93 RRVRRKAAADMLSRNISM---ILENLLKRYEQSQLPTHGQGVPTVVQTNILIRSMGPVSELDMDY 154
            |.|......|....||::   ||:.||..|:....|..|..: |.|.|||.:.|.||||:.||:|
  Rat    77 RLVLANIQEDEAKNNITIFTRILDRLLDGYDNRLRPGLGDSI-TEVFTNIYVTSFGPVSDTDMEY 140

  Fly   155 SMDCYFRQYWRDKRLSFKGPIKSLSLSIKMLDKIWRPDTYFYNGKHSQIHMITVPNKLLRLDQNG 219
            ::|.:|||.|:|:||.||||:..|.|:..|..|||.|||:|:|||.|..|.:|:||||||:..:|
  Rat   141 TIDVFFRQKWKDERLKFKGPMNILRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRIQDDG 205

  Fly   220 GILYSMRLTIKATCPMELQNFPMDRQSCPLVIGSYGYINQQLIYEWK-NQDDAVSFVP-GMTLNQ 282
            .:||:||||::|.|||.|::||||..||||..|||.|...::.|.|. |..|:|...| |..|||
  Rat   206 TLLYTMRLTVQAECPMHLEDFPMDAHSCPLKFGSYAYTTSEVTYIWTYNASDSVQVAPDGSRLNQ 270

  Fly   283 FDLISMMHRNFTTVRREGDFSVLHVAFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREATSDR 347
            :||:.......|.....|:::|:...|:|||..|||:||.|:|||:.|:||.||||::||:...|
  Rat   271 YDLLGQSIGKETIKSSTGEYTVMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPAR 335

  Fly   348 VSLCVTSVLTLSTISLDSRTDLPKVKYATALDWFLLMSFLYCIATLLEFAGVHYFTKLGSGESPQ 412
            ....||:|||::|:|:.:|..||||.||||:|||:.:.:.:..:.|:|||.|:||||.|..
  Rat   336 TVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGWA---- 396

  Fly   413 LEDQWEDICIANSLSDHAGEVDGDGEADADPFADEDSSNGSENDDNEAGASESVESKSGVCVCNK 477
                |:...:.|                     |:....||....|.|
  Rat   397 ----WDGKSVVN---------------------DKKKEKGSVMIQNNA----------------- 419

  Fly   478 NDALGLEYEVSLQNSLAGAGFLKRNAIFCPTYN-DPSYILPNTMERTTQTEPPAVSRLHQMWMCL 541
                   |.|::.|             :.|..: ||  :|....:..|..||.
  Rat   420 -------YAVAVAN-------------YAPNLSKDP--VLSTISKSATTPEPN------------ 450

  Fly   542 KSDNSFRKQRERNAAAQKSEQGGANCYVNSVSLIDRVARIAFPMSFAFLNLLYWWAY 598
                  :|...:.|.|:|:        .||||.|||::||.||:.|...||:||..|
  Rat   451 ------KKPENKPAEAKKT--------FNSVSKIDRMSRIVFPVLFGTFNLVYWATY 493

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8916	NP_573090.3	LIC	92..598	CDD:455710	187/510 (37%)
		LGIC_ECD_GABAR_GRD-like	132..314	CDD:349808	89/183 (49%)
		Cys-loop	233..247	CDD:349808	8/13 (62%)
Gabra2	XP_017454595.1	LIC	64..493	CDD:455710	187/510 (37%)
		LGIC_ECD_GABAAR_A2	100..302	CDD:349836	94/202 (47%)
		Cys-loop	219..233	CDD:349836	8/13 (62%)