Protein Alignment CG8916 and lgc-58

DIOPT Version :10

• Sequence 1: NP_573090.3
• Gene: CG8916 / 32553
• FlyBaseID: FBgn0030707
• Length: 612
• Species: Drosophila melanogaster
• Sequence 2: NP_001368738.1
• Gene: lgc-58 / 191637
• WormBaseID: WBGene00001587
• Length: 553
• Species: Caenorhabditis elegans
• Alignment Length: 573
• Identity: 155/573 - (27%)
• Similarity: 258/573 - (45%)
• Gaps: 115/573 - (20%)

  Fly   105 SRNISMILENLLKR----YEQSQLPT-HGQGVPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYW 164
            |..:.:.|:|||..    |:....|. |.:...|||:..:.|..|.......||:.:|.||:|:|
 Worm    23 SEPVPIYLDNLLNAGRQVYDNQSPPVQHDKEEVTVVELAMYIEGMSSFRTQTMDFQLDVYFQQFW 87

  Fly   165 RDKRLSFKGPIKSLSLSIKMLDKIWRPDTYFYNGKHSQIHMITVPNKLLRLDQNGGILYSMRLTI 229
            ||.||:.....:.|.....:|.|:|:||.||.|.:.::.|.:|.||.|:.:..:|.|||..|:::
 Worm    88 RDPRLAHNETRRVLVKDKAVLHKMWKPDVYFANARIAEFHEVTQPNFLVWIQPDGSILYDTRISM 152

  Fly   230 KATCPMELQNFPMDRQSCPLVIGSYGYINQQLIYEWKNQDDAVSFVPGMTLNQFDLI----SMMH 290
            ...|.:.|:.:|:|.|.|.|.|.||.|..:||:.:|| :|:.::..|.:.::...::    .:..
 Worm   153 VVVCTLNLEKWPLDSQRCHLRILSYAYTTEQLVIKWK-EDEPITRNPNIAMSDMHIVDLYPGLCD 216

  Fly   291 RNFTTVRREGDFSVLHVAFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREATSDRVSLCVTSV 355
            .|::|    |.:|.:...|.:||...:.::|.|||..||||:||.|||:..||...||||.:|::
 Worm   217 GNYST----GTWSCVTAEFFVKREITHHVMQSYVPTTLIVVISWFSFWLDVEAVPARVSLAITTL 277

  Fly   356 LTLSTISLDSRTDLPKVKYATALDWFLLMSFLYCIATLLEFAGVHY------------------- 401
            |||||.:..:|..||:|.|..|:|.::....::....::||..|:|
 Worm   278 LTLSTQANAARMALPEVSYMKAIDVWMGACMMFVFGVMIEFTIVNYAQRQGRKWHRTDAEIVMAS 342

  Fly   402 --------------------------FTKLGSGESPQL-EDQWEDICIANSLSDHAGEVDGDGEA 439
                                      |.:|.:.|...| ||..|.|    :::|.|  .|...:|
 Worm   343 SLESVKSGNAEKKPSRGDLGAHARHLFLRLRTNERQHLVEDPPEQI----AMNDTA--YDTVSQA 401

  Fly   440 DADPFADEDSS---NGSENDDNEAGASESVESKSGVCVCNKNDALGLEYEVSLQNSLAGAGFLKR 501
            .::.|:||:::   ...:|:|.||......|.|                |.:|....
 Worm   402 YSNSFSDEEAAPVVQPPQNEDAEAQEEVWAEQK----------------ETNLSEVW-------- 442

  Fly   502 NAIFCPTYNDPSYILPNTMERTTQTEPPAV--SRLHQMWMCL------KSDNSFRKQRERNAAAQ 558
                  ..:||:..|.:..|:......|.:  .|.|..:...      |.::|.||:.:.::|.:
 Worm   443 ------KESDPAERLAHWNEKENDASSPLMGNGRAHVRYGAAEKMKNRKCNDSSRKKEKWSSAIK 501

  Fly   559 KSEQGGANCYV-------NSVSLIDRVARIAFPMSFAFLNLLYWWAYGMYKKE 604
            :.::...|..|       |....||:.:|..||::|...||.| |.|.:|.||
 Worm   502 QIQKHKRNGSVFGKIAGRNRAKKIDQTSRWIFPLTFIIFNLTY-WIYYLYWKE 553

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8916	NP_573090.3	LIC	92..598	CDD:455710	151/565 (27%)
		LGIC_ECD_GABAR_GRD-like	132..314	CDD:349808	58/185 (31%)
		Cys-loop	233..247	CDD:349808	5/13 (38%)
lgc-58	NP_001368738.1	LIC	30..548	CDD:455710	150/559 (27%)