Protein Alignment CG8916 and lgc-40

DIOPT Version :10

• Sequence 1: NP_573090.3
• Gene: CG8916 / 32553
• FlyBaseID: FBgn0030707
• Length: 612
• Species: Drosophila melanogaster
• Sequence 2: NP_001407536.1
• Gene: lgc-40 / 188854
• WormBaseID: WBGene00020767
• Length: 502
• Species: Caenorhabditis elegans
• Alignment Length: 534
• Identity: 144/534 - (26%)
• Similarity: 222/534 - (41%)
• Gaps: 100/534 - (18%)

  Fly    98 KAAADMLSRNISMILENLLKRYE-----QSQLPTHGQGVPTVVQTNILIRSMGPVSELDMDYSMD 157
            ||..|.|..      |.|..|:.     ...:..||.||||.|..::.|..|...|...|||.:|
 Worm    32 KAFLDKLKN------ETLYNRFATPTQYDEYIRVHGTGVPTNVTLSMFIEGMSSFSAQTMDYHLD 90

  Fly   158 CYFRQYWRDKRLSFKGPIKSLSLSIKMLDKIWRPDTYFYNGKHSQIHMITVPNKLLRLDQNGGIL 222
            .||::.|.|.||:.......|...:.:...:|.||.||.|.:.:....||..|.|:.:..||.:.
 Worm    91 VYFQEEWYDHRLAHNASAPILVRDLTVFKMMWHPDVYFANARSAAFQDITDDNFLVWVYPNGRVW 155

  Fly   223 YSMRLTIKATCPMELQNFPMDRQSCPLVIGSYGYINQQLIYEWKNQDD--AVSFVPGMTLNQFDL 285
            |..|::|.::|.|:|..:|:|.|.|.|.|.||.|....|...|..::|  |:...|.:|:....|
 Worm   156 YDARISIVSSCNMDLWKYPLDSQECALRILSYAYPMTVLRLLWSEKEDVPAIDRNPDITMPDMSL 220

  Fly   286 ISMMHRNFTTVRREGDFSVLHVAFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREATSDRVSL 350
            ..:...........|::|.:...|.::|...:.::|.|||..||||:||.:||:..::...||||
 Worm   221 KHIRTGYCNGTYATGEWSCMTAIFYVEREMMHHVMQTYVPTALIVVISWFNFWLEIDSAPARVSL 285

  Fly   351 CVTSVLTLSTISLDSRTDLPKVKYATALDWFLLMSFLYCIATLLEFAGVHYFTKL----GSGESP 411
            .:|::||:||.:...:..||:|.|..|:|.::.....:....::||...||...|    |.|:..
 Worm   286 SITTLLTISTQANAVKLALPEVSYMKAIDVWMGSCMAFVFGVMIEFTICHYAKNLEMLRGDGQPS 350

  Fly   412 QLED-----------QWEDIC--IANSLSDHAGEVDGDGEAD--ADPFADEDSSNGSENDDNEAG 461
            .:.|           ..:|:.  :| :|::..| |.||||..  .:....|:....|.|.:|:..
 Worm   351 LIVDTALSTLFGAARDIDDLVRKVA-TLNEEEG-VRGDGEQHIALNMLNPEEPRLRSLNQNNDVT 413

  Fly   462 ASESVESKSGVCVCNKNDALGLEYEVSLQNSLAGAGFLKRNAIFCPTYNDPSYILPNTMERTTQT 526
            |:                  |..|.|       ||..:||                       :.
 Worm   414 AN------------------GTRYFV-------GAERMKR-----------------------KR 430

  Fly   527 EPPAVSRLHQMWMCLK------SDNSFRKQRE-RNAAAQKSEQGGANCYVNSVSLIDRVARIAFP 584
            ...::|||.|....::      |..:|...|. ||...::..|           .||...||.||
 Worm   431 SKASLSRLRQQVASMRHATIDVSRRAFNWTRALRNLRGRRVAQ-----------RIDERCRIVFP 484

  Fly   585 MSFAFLNLLYWWAY 598
            |.|...|:.||..|
 Worm   485 MIFLLFNVAYWSFY 498

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8916	NP_573090.3	LIC	92..598	CDD:455710	143/532 (27%)
		LGIC_ECD_GABAR_GRD-like	132..314	CDD:349808	54/183 (30%)
		Cys-loop	233..247	CDD:349808	6/13 (46%)
lgc-40	NP_001407536.1	LIC	31..498	CDD:455710	143/532 (27%)