Protein Alignment CG8916 and lgc-50

DIOPT Version :9

• Sequence 1: NP_573090.3
• Gene: CG8916 / 32553
• FlyBaseID: FBgn0030707
• Length: 612
• Species: Drosophila melanogaster
• Sequence 2: NP_498637.3
• Gene: lgc-50 / 188633
• WormBaseID: WBGene00020605
• Length: 491
• Species: Caenorhabditis elegans
• Alignment Length: 542
• Identity: 135/542 - (24%)
• Similarity: 233/542 - (42%)
• Gaps: 95/542 - (17%)

  Fly    84 YSSSEISNQRRVRRKAAADMLSRNISMILENLLKRYEQSQLPTHGQGVPTVVQTNILIRSMGPVS 148
            :|::..::.::..|.      |.|:..:::.||..|:...|| ..:||...::.:  ::.:..:|
 Worm    14 FSAATTNSPKKCSRN------SINLGKLIDTLLTDYDTHLLP-EAEGVNVTIELH--VQGVSGIS 69

  Fly   149 ELDMDYSMDCYFRQYWRDKRLSFKG---PIKSLSLSIKMLDKIWRPDTYFYNGKHSQIHMITVPN 210
            |:..|:|:|..:.:.|:|.|||||.   ...:::|......|||.|||...|.|.|.||.....|
 Worm    70 EITGDFSLDVMYSEIWQDPRLSFKHLNVCATNITLKSDFRKKIWTPDTCIINSKSSSIHSSPSEN 134

  Fly   211 KLLRLDQNGGILYSMRLTIKATCPMELQNFPMDRQSCPLVIGSYGYINQQLIYEWKNQDDAVSFV 275
            ..:.|.:||.:..:.||.:|..|.:.|:.||.|..||.:|:.||.:...::...|  .|..::.:
 Worm   135 TFVILYENGLVWSNFRLNVKTPCSVNLKMFPFDSLSCEIVLESYSFNTDEVRLMW--HDVPITMM 197

  Fly   276 PGMTLNQFDLISMMHRNFTTVRREGDFSVLHVAFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIH 340
            ..:.|..||||.....:.......|.:....|.|...|..|::|.|.|.|..|.|:.|||.|:..
 Worm   198 EKVELPDFDLIGWSTDHQRLEYPNGIWDRAKVKFTFARRYGFYLFQSYFPTSLTVISSWVGFFFD 262

  Fly   341 REATSDRVSLCVTSVLTLSTISLDSRTDLPKVKYATALDWFLLMSFLYCIATLLEFAGVHYFTKL 405
            ..:.|.|::|.|:|:|.|:....:....||:|.|...||.:::.|.::...||:|.|.|
 Worm   263 VRSVSARITLGVSSLLALTFQFGNVLRHLPRVSYIKCLDVWMIFSVIFIFCTLVELAIV------ 321

  Fly   406 GSGESPQLEDQWE-DICIANSLSDH-AGEVDGDGEADADPFADEDSSNGSENDDNEAGASESVES 468
                 .|| ::|| :..|.:.:..| ..::....:.::.  |||....|       .|.
 Worm   322 -----CQL-NRWERERQIGSKVLGHWLNQIRKTRKKESK--ADEGGGGG-------VGG------ 365

  Fly   469 KSGVCVCNKNDALGLEYEVSLQNSLAGAGFLKRNAIFCPTYNDPSYILPNTMERTTQTEPPAVSR 533
                 :..|...:..:.:.:..:|.:||                      ....||..:||. :.
 Worm   366 -----LLRKRIPVLAQLKAAATDSNSGA----------------------ATAMTTAIQPPN-TN 402

  Fly   534 LHQMWMCLKSDNSFRKQR-----ERNAAAQKSEQGGANCY---------------VNSVSLIDRV 578
            |:.:   ..||||.....     |....|.:.::|.::|:               :.||. :||.
 Worm   403 LNSI---TNSDNSKLVANNFTSIEHETYAYEKKRGFSHCFQRFVYAICPPDRDWTITSVQ-VDRC 463

  Fly   579 ARIAFPMSFAFLNLLYWWAYGM 600
            :.|.||:||...|::||..|.|
 Worm   464 SMIMFPLSFLIFNVVYWSIYFM 485

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8916	NP_573090.3	LIC	92..598	CDD:273305	132/530 (25%)
		Neur_chan_LBD	111..315	CDD:280998	59/206 (29%)
		Neur_chan_memb	322..>403	CDD:280999	27/80 (34%)
lgc-50	NP_498637.3	LIC	34..483	CDD:273305	129/512 (25%)
		Neur_chan_LBD	34..237	CDD:280998	59/207 (29%)
		Neur_chan_memb	245..480	CDD:280999	65/293 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810