Protein Alignment CG8916 and glc-1

DIOPT Version :10

• Sequence 1: NP_573090.3
• Gene: CG8916 / 32553
• FlyBaseID: FBgn0030707
• Length: 612
• Species: Drosophila melanogaster
• Sequence 2: NP_507090.1
• Gene: glc-1 / 180086
• WormBaseID: WBGene00001591
• Length: 461
• Species: Caenorhabditis elegans
• Alignment Length: 500
• Identity: 145/500 - (28%)
• Similarity: 225/500 - (45%)
• Gaps: 117/500 - (23%)

  Fly   109 SMILENLL-KRYEQSQLPTHGQGVPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDKRLSF- 171
            |.||.:|. ..|:....|....|.|.||..|:|:|::..:..::|:||.....|:.|.|||||:
 Worm    64 SKILAHLFTSGYDFRVRPPTDNGGPVVVSVNMLLRTISKIDVVNMEYSAQLTLRESWIDKRLSYG 128

  Fly   172 -KGPIKSLSLSIKMLDKIWRPDTYFYNGKHSQIHMITVPNKLLRLDQNGGILYSMRLTIKATCPM 235
             ||..:...:.:.:..:||.|||:|.|.|.:..|.|..||.|:|:..:|.:|||:|:::..:|||
 Worm   129 VKGDGQPDFVILTVGHQIWMPDTFFPNEKQAYKHTIDKPNVLIRIHNDGTVLYSVRISLVLSCPM 193

  Fly   236 ELQNFPMDRQSCPLVIGSYGYINQQLIYEWKNQDDAVSFVPGM--TLNQFDLISMMHRNFTTVRR 298
            .||.:|||.|.|.:.:.||.|..:.:.|.|| :...:....|:  :|..|.|.:......|:|..
 Worm   194 YLQYYPMDVQQCSIDLASYAYTTKDIEYLWK-EHSPLQLKVGLSSSLPSFQLTNTSTTYCTSVTN 257

  Fly   299 EGDFSVLHVAFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREATSDRVSLCVTSVLTLSTISL 363
            .|.:|.|.....|||...::|:|:|:|..::|::||||||..|.|...||:|.||::||::..|.
 Worm   258 TGIYSCLRTTIQLKREFSFYLLQLYIPSCMLVIVSWVSFWFDRTAIPARVTLGVTTLLTMTAQSA 322

  Fly   364 DSRTDLPKVKYATALD-WF-LLMSFLYCIATLLEFAGVHYFTKLGSGESPQLEDQWEDICIANSL 426
            ...:.||.|.|..|:| |. ..|:|::|  .|||||.|::                    |||
 Worm   323 GINSQLPPVSYIKAIDVWIGACMTFIFC--ALLEFALVNH--------------------IAN-- 363

  Fly   427 SDHAGEVDGDGEADADPFADEDSSNGSENDDNEAGASESVESKSGVCVCNKNDALGLEYEVSLQN 491
                                                .:.||.|:..   .:..|     |:.|..
 Worm   364 ------------------------------------KQGVERKART---EREKA-----EIPLLQ 384

  Fly   492 SLAGAGFLKRNAIFCPTYND-PSYILPNTMERTTQTEPPAVSRLHQMWMCLKSDNSFRKQRERNA 555
            :|               :|| |:.:.  ..|...:|.|     |::..|     |||     .|.
 Worm   385 NL---------------HNDVPTKVF--NQEEKVRTVP-----LNRRQM-----NSF-----LNL 417

  Fly   556 AAQKSEQGGANCYVNSVS-LIDRVARIAFPMSFAFLNLLYWWAYG 599
            ...|:|.       |.:| .:|.::|..||:.|...|:|||..:|
 Worm   418 LETKTEW-------NDISKRVDLISRALFPVLFFVFNILYWSRFG 455

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8916	NP_573090.3	LIC	92..598	CDD:455710	144/497 (29%)
		LGIC_ECD_GABAR_GRD-like	132..314	CDD:349808	64/185 (35%)
		Cys-loop	233..247	CDD:349808	9/13 (69%)
glc-1	NP_507090.1	LIC	65..452	CDD:455710	142/494 (29%)