Protein Alignment CG8916 and lgc-49

DIOPT Version :10

• Sequence 1: NP_573090.3
• Gene: CG8916 / 32553
• FlyBaseID: FBgn0030707
• Length: 612
• Species: Drosophila melanogaster
• Sequence 2: NP_505841.2
• Gene: lgc-49 / 179547
• WormBaseID: WBGene00010741
• Length: 457
• Species: Caenorhabditis elegans
• Alignment Length: 500
• Identity: 124/500 - (24%)
• Similarity: 204/500 - (40%)
• Gaps: 119/500 - (23%)

  Fly   111 ILENLLK--RYEQSQLPTHGQGVPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDKRLSFK- 172
            |::.||.  .|.:.::|.. .|||  ||....::::..::|:..|:.||.|..:.|.|..|.|.
 Worm    57 IIDKLLNGTGYNKFRIPNE-NGVP--VQVEFWVQAITSINEITNDFEMDIYINEMWLDPALKFDH 118

  Fly   173 -GPIK-SLSLSIKMLDKIWRPDTYFYNGKHSQIHMITVPNKLLRLDQNGGILYSMRLTIKATCPM 235
             .|.| :||:|.::|:::|.|::.|.|.|.::||.....|..|.:..||.:..:.|:.:|..|.:
 Worm   119 LNPCKQNLSVSHQVLEQLWTPNSCFVNSKFAEIHDSPFKNVFLMIYPNGTVWVNYRVNVKGPCDL 183

  Fly   236 ELQNFPMDRQSCPLVIGSYGYINQQLIYEWKNQD-DAVSFVPGMTLNQFDLISMMHRNFTTVRRE 299
            .|:.||:|.|.|.|:..|:.|.||::...|..:. :.||....:.|..|:||.:.....:.....
 Worm   184 SLELFPLDIQECHLIYESFNYNNQEVRMRWNEKSAEPVSVTNKIRLPDFELIKIESTRISAPYPA 248

  Fly   300 GDFSVLHVAFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREATSDRVSLCVTSVLTLSTISLD 364
            |.:..|||....:|...::.:|.|:|..|.:.:||:||.:..:|...|..|.|.::|.:.....:
 Worm   249 GMWDELHVKLVFERRYIWYFMQAYLPTYLTIFISWISFSLGTKAMPARTMLGVNALLAMIFQFGN 313

  Fly   365 SRTDLPKVKYATALDWFLLMSFLYCIATLLEFAGVHYFTKLGSGESPQLEDQWEDICIANSLSDH 429
            ...:||:|.|..|:|.::|:|..:...:|||.|.|.|.||...|...:        |....|.|:
 Worm   314 IMRNLPRVSYVKAIDVWMLVSMTFIFLSLLELAIVGYKTKNEEGSKKK--------CPHKKLLDN 370

  Fly   430 AGEVDGDGEADADPFADEDSSNGSENDDNEAGASESVESKSGVCVCNKNDALGLEYEVSLQNSLA 494
                     .:|.|                          :|:|...|...|.:|     :.|..
 Worm   371 ---------FEASP--------------------------AGLCRYEKRFMLPVE-----RRSAR 395

  Fly   495 GAGFLKRNAIFCPTYNDPSYILPNTMERTTQTEPPAVSRLHQMWMCLKSDNSFRKQRERNAAAQK 559
            ..|.: |..:|...:|                           |
 Worm   396 WGGII-RFQVFQDFWN---------------------------W--------------------- 411

  Fly   560 SEQGGANCYVNSVSLIDRVARIAFPMSFAFLNLLYWWAYGMYKKE 604
                       |...||||:.|.||..||..|::||..|  |.|:
 Worm   412 -----------SPEKIDRVSAIMFPACFAIFNIVYWSYY--YNKK 443

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8916	NP_573090.3	LIC	92..598	CDD:455710	121/492 (25%)
		LGIC_ECD_GABAR_GRD-like	132..314	CDD:349808	54/185 (29%)
		Cys-loop	233..247	CDD:349808	6/13 (46%)
lgc-49	NP_505841.2	LIC	53..439	CDD:455710	121/492 (25%)
		LGIC_ECD_GABAAR	78..263	CDD:349791	55/186 (30%)
		Cys-loop	181..195	CDD:349791	6/13 (46%)