Protein Alignment CG8916 and mod-1

DIOPT Version :10

• Sequence 1: NP_573090.3
• Gene: CG8916 / 32553
• FlyBaseID: FBgn0030707
• Length: 612
• Species: Drosophila melanogaster
• Sequence 2: NP_741580.1
• Gene: mod-1 / 179269
• WormBaseID: WBGene00003386
• Length: 489
• Species: Caenorhabditis elegans
• Alignment Length: 524
• Identity: 131/524 - (25%)
• Similarity: 234/524 - (44%)
• Gaps: 89/524 - (16%)

  Fly    96 RRKAAADMLSRNISMILENLLKRYEQSQLPTHGQGVPTVVQTNILIRSMGPVSELDMDYSMDCYF 160
            |||......|.  ..|:..::..|.: .||.....|.  |...|.::.||.::|:..|:.:|..|
 Worm    24 RRKCPEGAWSE--GKIMNTIMSNYTK-MLPDAEDSVQ--VNIEIHVQDMGSLNEISSDFEIDILF 83

  Fly   161 RQYWRDKRLSFKG-PI--KSLSLSIKMLDKIWRPDTYFYNGKHSQIHMITVPNKLLRLDQNGGIL 222
            .|.|.|..|||.. |.  :::::..::|.|||.|:|...|.|.:.:|.....|.::.|.:||.:.
 Worm    84 TQLWHDSALSFAHLPACKRNITMETRLLPKIWSPNTCMINSKRTTVHASPSENVMVILYENGTVW 148

  Fly   223 YSMRLTIKATCPMELQNFPMDRQSCPLVIGSYGYINQQLIYEWKNQDDAVSFVPGMTLNQFDLIS 287
            .:.||::|:.|.::|:.||.|.|:|.|:..||.:.::::...|  .::||:.:..:.|..||::.
 Worm   149 INHRLSVKSPCNLDLRQFPFDTQTCILIFESYSHNSEEVELHW--MEEAVTLMKPIQLPDFDMVH 211

  Fly   288 MMHRNFTTVRREGDFSVLHVAFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREATSDRVSLCV 352
            ...:..|.:...|.:..|.|.|..||..|:::||.|||..|.:::|||||.:..:|...|.::.:
 Worm   212 YSTKKETLLYPNGYWDQLQVTFTFKRRYGFYIIQAYVPTYLTIIVSWVSFCMEPKALPARTTVGI 276

  Fly   353 TSVLTLSTISLDSRTDLPKVKYATALDWFLLMSFLYCIATLLEFAGVHYFTKLGSG--------E 409
            :|:|.|:....:...:||:|.|..|:|.::|....:...|::|.|.|.|.::..:.        |
 Worm   277 SSLLALTFQFGNILKNLPRVSYVKAMDVWMLGCISFVFGTMVELAFVCYISRCQNSVRNAERRRE 341

  Fly   410 SPQLEDQWEDICIANSLSDHAGEVDGDGEADADPFADEDS--------SNGSENDDNEAGASESV 466
            ..:....|               .:|.....::.:|:..|        |||:.|:
 Worm   342 RMRNSQVW---------------ANGSCRTRSNGYANGGSVISHYHPTSNGNGNN---------- 381

  Fly   467 ESKSGVCVCNKNDALGLEYEVSLQNSLAGAGFLKRNAIFCPTYNDPSYILPNTMERTT-QTEPPA 530
                     |::|.          ..:.|.|.|.||       ..||   |..::.|| .:|.|.
 Worm   382 ---------NRHDT----------PQVTGRGSLHRN-------GPPS---PLNLQMTTFDSEIPL 417

  Fly   531 VSRLHQMWMCLKSDNSFRKQRERNAAAQKSEQGGANCYVN-SVSLIDRVARIAFPMSFAFLNLLY 594
            .  ..|:.:.::||....::....:....|     .|... ....:|:.:.:|||::|...||:|
 Worm   418 T--FDQLPVSMESDRPLIEEMRSTSPPPPS-----GCLARFHPEAVDKFSIVAFPLAFTMFNLVY 475

  Fly   595 WWAY 598
            ||.|
 Worm   476 WWHY 479

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8916	NP_573090.3	LIC	92..598	CDD:455710	130/522 (25%)
		LGIC_ECD_GABAR_GRD-like	132..314	CDD:349808	53/184 (29%)
		Cys-loop	233..247	CDD:349808	6/13 (46%)
mod-1	NP_741580.1	LIC	7..479	CDD:455710	130/522 (25%)
		LGIC_ECD_GABAAR	56..238	CDD:349791	54/185 (29%)
		Cys-loop	159..173	CDD:349791	6/13 (46%)