Protein Alignment CG8916 and lgc-37

DIOPT Version :9

• Sequence 1: NP_573090.3
• Gene: CG8916 / 32553
• FlyBaseID: FBgn0030707
• Length: 612
• Species: Drosophila melanogaster
• Sequence 2: NP_499662.2
• Gene: lgc-37 / 176694
• WormBaseID: WBGene00013914
• Length: 483
• Species: Caenorhabditis elegans
• Alignment Length: 532
• Identity: 171/532 - (32%)
• Similarity: 274/532 - (51%)
• Gaps: 100/532 - (18%)

  Fly    84 YSSSEISNQRRVRRKAAA----DMLSRNISMILENLLKRYEQSQLPTHGQGVPTVVQTNILIRSM 144
            :.|..:.:.:|.|..:.:    ..|.|..:.:|:.:|...:::..|.:....|..|:.:|.||||
 Worm    16 HHSQAVIDMKRQRLSSRSTTYNQTLIRYTTKVLDTILLNQDKNFRPVNPDNSPLQVEVDISIRSM 80

  Fly   145 GPVSELDMDYSMDCYFRQYWRDKRLSFK--GPIK-SLSLSIKMLDKIWRPDTYFYNGKHSQIHMI 206
            |||||.:|::|:||||||.|.|:||:|.  .|.| .:.|:.|||..||.||||..||:.|.:|.:
 Worm    81 GPVSEQNMEFSLDCYFRQKWLDRRLAFTPINPSKPEIPLASKMLKDIWIPDTYIRNGRKSYLHTL 145

  Fly   207 TVPNKLLRLDQNGGILYSMRLTIKATCPMELQNFPMDRQSCPLVIGSYGYINQQLIYEWKNQD-D 270
            ||||.|.|:..:|.:..|.||||::.|.|.|:.||||.|:||:.:||.||.::.::|:||:.: |
 Worm   146 TVPNILFRVRSDGQVHVSQRLTIRSRCQMFLKKFPMDTQACPIEVGSLGYFSKDVVYKWKDVELD 210

  Fly   271 AVSFVPGMTLNQFDLISM--MHRNFTTVR-REGDFSVLHVAFNLKRHTGYFLIQVYVPCILIVVL 332
            |..   |.||:|:.::|:  ..||.:..| .:.:.|||:|.|.|:|..||:::|:|.||.|:||:
 Worm   211 AKM---GNTLSQYQVLSLSKSERNVSDFRFSDRNISVLNVYFKLQRQQGYYILQIYTPCTLVVVM 272

  Fly   333 SWVSFWIHREATSDRVSLCVTSVLTLSTISLDSRTDLPKVKYATALDWFLLMSFLYCIATLLEFA 397
            |||||||::||:..||||.:.:||::|||....|||||||.::||||.::|..|::..|.::|:|
 Worm   273 SWVSFWINKEASPARVSLGIMTVLSMSTIGFGLRTDLPKVSHSTALDVYILTCFVFLFAAMVEYA 337

  Fly   398 GVHYFTKLGSGESPQLEDQWEDICIANSLSDHAGEVDGDGEADADPFADEDSSNGSENDDNEAGA 462
            .::|.               :.:.|...:.|..|
 Worm   338 VINYA---------------QIVYIRKQIHDLKG------------------------------- 356

  Fly   463 SESVESKSGVCVCNKNDALGLEYEVSLQNSLAGAGFLKRNAIFCPTYNDPSYILPNTMERTTQTE 527
                        ..:|.|:|..:...|.      |..:|:.|              .::..|..:
 Worm   357 ------------LEQNTAMGQMFTAGLM------GARRRDTI--------------QVDDLTVEK 389

  Fly   528 PPAVSRLHQMW--MCLKSD----NSFRKQRERNAAAQKSEQGGANCYVNSVSLIDRVARIAFPMS 586
            ..|..:....|  :|.|.:    :.|.:...:.|.|:|:.:.|....|  |:.||..:::|||..
 Worm   390 EEARLKAVPWWKKLCFKDEQGNTSMFYRMAVKAAIAKKTLRNGDPAEV--VNKIDNFSKLAFPTL 452

  Fly   587 FAFLNLLYWWAY 598
            :...|:.||.||
 Worm   453 YIIFNVFYWVAY 464

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8916	NP_573090.3	LIC	92..598	CDD:273305	168/522 (32%)
		Neur_chan_LBD	111..315	CDD:280998	90/210 (43%)
		Neur_chan_memb	322..>403	CDD:280999	41/80 (51%)
lgc-37	NP_499662.2	LIC	44..464	CDD:273305	164/502 (33%)
		Neur_chan_LBD	45..254	CDD:280998	89/211 (42%)
		Neur_chan_memb	262..461	CDD:280999	69/278 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H20220
Inparanoid	1	1.050	324	1.000	Inparanoid score	I1470
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1057372at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR18945
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3154
SonicParanoid	1	1.000	-	-		X127
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	9	9.000