Protein Alignment CG8916 and lgc-37

DIOPT Version :10

• Sequence 1: NP_573090.3
• Gene: CG8916 / 32553
• FlyBaseID: FBgn0030707
• Length: 612
• Species: Drosophila melanogaster
• Sequence 2: NP_499662.2
• Gene: lgc-37 / 176694
• WormBaseID: WBGene00013914
• Length: 483
• Species: Caenorhabditis elegans
• Alignment Length: 532
• Identity: 171/532 - (32%)
• Similarity: 274/532 - (51%)
• Gaps: 100/532 - (18%)

  Fly    84 YSSSEISNQRRVRRKAAA----DMLSRNISMILENLLKRYEQSQLPTHGQGVPTVVQTNILIRSM 144
            :.|..:.:.:|.|..:.:    ..|.|..:.:|:.:|...:::..|.:....|..|:.:|.||||
 Worm    16 HHSQAVIDMKRQRLSSRSTTYNQTLIRYTTKVLDTILLNQDKNFRPVNPDNSPLQVEVDISIRSM 80

  Fly   145 GPVSELDMDYSMDCYFRQYWRDKRLSFK--GPIK-SLSLSIKMLDKIWRPDTYFYNGKHSQIHMI 206
            |||||.:|::|:||||||.|.|:||:|.  .|.| .:.|:.|||..||.||||..||:.|.:|.:
 Worm    81 GPVSEQNMEFSLDCYFRQKWLDRRLAFTPINPSKPEIPLASKMLKDIWIPDTYIRNGRKSYLHTL 145

  Fly   207 TVPNKLLRLDQNGGILYSMRLTIKATCPMELQNFPMDRQSCPLVIGSYGYINQQLIYEWKNQD-D 270
            ||||.|.|:..:|.:..|.||||::.|.|.|:.||||.|:||:.:||.||.::.::|:||:.: |
 Worm   146 TVPNILFRVRSDGQVHVSQRLTIRSRCQMFLKKFPMDTQACPIEVGSLGYFSKDVVYKWKDVELD 210

  Fly   271 AVSFVPGMTLNQFDLISM--MHRNFTTVR-REGDFSVLHVAFNLKRHTGYFLIQVYVPCILIVVL 332
            |..   |.||:|:.::|:  ..||.:..| .:.:.|||:|.|.|:|..||:::|:|.||.|:||:
 Worm   211 AKM---GNTLSQYQVLSLSKSERNVSDFRFSDRNISVLNVYFKLQRQQGYYILQIYTPCTLVVVM 272

  Fly   333 SWVSFWIHREATSDRVSLCVTSVLTLSTISLDSRTDLPKVKYATALDWFLLMSFLYCIATLLEFA 397
            |||||||::||:..||||.:.:||::|||....|||||||.::||||.::|..|::..|.::|:|
 Worm   273 SWVSFWINKEASPARVSLGIMTVLSMSTIGFGLRTDLPKVSHSTALDVYILTCFVFLFAAMVEYA 337

  Fly   398 GVHYFTKLGSGESPQLEDQWEDICIANSLSDHAGEVDGDGEADADPFADEDSSNGSENDDNEAGA 462
            .::|.               :.:.|...:.|..|
 Worm   338 VINYA---------------QIVYIRKQIHDLKG------------------------------- 356

  Fly   463 SESVESKSGVCVCNKNDALGLEYEVSLQNSLAGAGFLKRNAIFCPTYNDPSYILPNTMERTTQTE 527
                        ..:|.|:|..:...|.      |..:|:.|              .::..|..:
 Worm   357 ------------LEQNTAMGQMFTAGLM------GARRRDTI--------------QVDDLTVEK 389

  Fly   528 PPAVSRLHQMW--MCLKSD----NSFRKQRERNAAAQKSEQGGANCYVNSVSLIDRVARIAFPMS 586
            ..|..:....|  :|.|.:    :.|.:...:.|.|:|:.:.|....|  |:.||..:::|||..
 Worm   390 EEARLKAVPWWKKLCFKDEQGNTSMFYRMAVKAAIAKKTLRNGDPAEV--VNKIDNFSKLAFPTL 452

  Fly   587 FAFLNLLYWWAY 598
            :...|:.||.||
 Worm   453 YIIFNVFYWVAY 464

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8916	NP_573090.3	LIC	92..598	CDD:455710	168/522 (32%)
		LGIC_ECD_GABAR_GRD-like	132..314	CDD:349808	86/188 (46%)
		Cys-loop	233..247	CDD:349808	8/13 (62%)
lgc-37	NP_499662.2	LIC	44..464	CDD:455710	164/502 (33%)
		LGIC_ECD	68..254	CDD:475126	86/188 (46%)