Protein Alignment CG8916 and Glrb

DIOPT Version :9

• Sequence 1: NP_573090.3
• Gene: CG8916 / 32553
• FlyBaseID: FBgn0030707
• Length: 612
• Species: Drosophila melanogaster
• Sequence 2: XP_036018791.1
• Gene: Glrb / 14658
• MGIID: 95751
• Length: 530
• Species: Mus musculus
• Alignment Length: 514
• Identity: 151/514 - (29%)
• Similarity: 236/514 - (45%)
• Gaps: 75/514 - (14%)

  Fly   109 SMILENLLKRYEQSQLPTHGQGVPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDKRL---- 169
            |.||..||..|:....|.. :|:|..|..||.|.|.|.:.|..|||.::.:.||.|.|.||
Mouse    67 SNILNRLLVSYDPRIRPNF-KGIPVDVVVNIFINSFGSIQETTMDYRVNIFLRQKWNDPRLKLPS 130

  Fly   170 SFKGPIKSLSLSIKMLDKIWRPDTYFYNGKHSQIHMITVPNKLLRLDQNGGILYSMRLTIKATCP 234
            .|:|. .:|::...|...:|:||.:|.|.|.:..|.:|..|.||.:.::|.:|.||||:|..:||
Mouse   131 DFRGS-DALTVDPTMYKCLWKPDLFFANEKSANFHDVTQENILLFIFRDGDVLVSMRLSITLSCP 194

  Fly   235 MELQNFPMDRQSCPLVIGSYGYINQQLIYEWKNQDDAVSFVPGMTLNQFDL--ISMMHRNFTT-V 296
            ::|..||||.|.|.:.:.|:||....|.:.|::.|...  :..:.|.|||:  ..:.:.|.|. .
Mouse   195 LDLTLFPMDTQRCKMQLESFGYTTDDLRFIWQSGDPVQ--LEKIALPQFDIKKEDIEYGNCTKYY 257

  Fly   297 RREGDFSVLHVAFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREATSDRVSLCVTSVLTLSTI 361
            :..|.::.:.|.|.|:|..|::::.||.|.:|||||||:||||:.:|::.||.|.:.|||:|::.
Mouse   258 KGTGYYTCVEVIFTLRRQVGFYMMGVYAPTLLIVVLSWLSFWINPDASAARVPLGIFSVLSLASE 322

  Fly   362 SLDSRTDLPKVKYATALDWFLLMSFLYCIATLLEFAGVHYFTKLGSGESPQLEDQWEDICIANSL 426
            ......:||||.|..|||.:|:...|:..|:|:|:|.|....     .:|:..:. |...||.
Mouse   323 CTTLAAELPKVSYVKALDVWLIACLLFGFASLVEYAVVQVML-----NNPKRVEA-EKARIAK-- 379

  Fly   427 SDHAGEVDGDGEADADPFADEDSSNGSENDDNEAGASESVESKSGV-CVCNK---------NDAL 481
               |.:.||.|           .:...:|..|..|....:.:...: .||.:         .|.|
Mouse   380 ---AEQADGKG-----------GNAAKKNTVNGTGTPVHISTLQELPMVCQQITYQLDGWPTDTL 430

  Fly   482 GLEY-EVSLQNSLAGAGFLKRNAIFCPTYNDPSYI--LPNTMERTTQTEPPAVSRLHQMWMC--- 540
            ..:. |...:........|:.        ||.|.:  ||...|.:.             :.|
Mouse   431 TTQVGETRCKKVCTSKSDLRS--------NDFSIVGSLPRDFELSN-------------YDCYGK 474

  Fly   541 -LKSDNSFRKQRERNAAAQKSEQGGANCYVNSVSLIDRVARIAFPMSFAFLNLLYWWAY 598
             ::.:|...|.:.:|    |...........:...||..||..||..|.|.|::||..|
Mouse   475 PIEVNNGLGKPQAKN----KKPPPAKPVIPTAAKRIDLYARALFPFCFLFFNVIYWSIY 529

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8916	NP_573090.3	LIC	92..598	CDD:273305	150/512 (29%)
		Neur_chan_LBD	111..315	CDD:280998	72/210 (34%)
		Neur_chan_memb	322..>403	CDD:280999	37/80 (46%)
Glrb	XP_036018791.1	LIC	64..529	CDD:273305	150/512 (29%)
		LGIC_ECD_GlyR_beta	89..275	CDD:349811	64/188 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	3	2.770