Protein Alignment CG8916 and Gabrg3

DIOPT Version :10

• Sequence 1: NP_573090.3
• Gene: CG8916 / 32553
• FlyBaseID: FBgn0030707
• Length: 612
• Species: Drosophila melanogaster
• Sequence 2: XP_017177467.1
• Gene: Gabrg3 / 14407
• MGIID: 95624
• Length: 468
• Species: Mus musculus
• Alignment Length: 526
• Identity: 162/526 - (30%)
• Similarity: 245/526 - (46%)
• Gaps: 109/526 - (20%)

  Fly    90 SNQRRVRRKAAADMLSRNISMILENLLKRYEQSQLPTHGQGVPTVVQTNILIRSMGPVSELDMDY 154
            |||:.|....:.|   .::::||..||:.|::...|..|. .|||:..:|.:.|:||||.::|:|
Mouse    32 SNQKWVLAPKSQD---TDVTLILNKLLREYDKKLRPDIGI-KPTVIDVDIYVNSIGPVSSINMEY 92

  Fly   155 SMDCYFRQYWRDKRLSFKGPIKSLSLSIKMLDKIWRPDTYFYNGKHSQIHMITVPNKLLRLDQNG 219
            .:|.:|.|.|.|.||.|...:|.|:|:..|:..||.|||.|.|.|.::.|.||.||:|||:..:|
Mouse    93 QIDIFFAQTWTDSRLRFNSTMKILTLNSNMVGLIWIPDTIFRNSKTAEAHWITTPNQLLRIWNDG 157

  Fly   220 GILYSMRLTIKATCPMELQNFPMDRQSCPLVIGSYGYINQQLIYEWKNQDDAVSFVPGMTLNQFD 284
            .|||::||||.|.|.::|.|||||..:|||...||||..:::||.|:......:......|.|||
Mouse   158 KILYTLRLTINAECQLQLHNFPMDAHACPLTFSSYGYPKEEMIYRWRKNSVEAADQKSWRLYQFD 222

  Fly   285 LISMMHRNFTTVRREGDFSVLHVAFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREATSDRVS 349
            .:.:.:.........||:.|:.:.|.|.|..|||.||.|:||||.||||||||||.::||..|.:
Mouse   223 FMGLRNTTEIVTTSAGDYVVMTIYFELSRRMGYFTIQTYIPCILTVVLSWVSFWIKKDATPARTT 287

  Fly   350 LCVTSVLTLSTISLDSRTDLPKVKYATALDWFLLMSFLYCIATLLEFAGVHYFTKLGSGESPQLE 414
            |.:|:|||::|:|..:|..||:|.|.||:|.|:.:.||:..|.|:|:|.::|::   |...|
Mouse   288 LGITTVLTMTTLSTIARKSLPRVSYVTAMDLFVTVCFLFVFAALMEYATLNYYS---SCRKP--- 346

  Fly   415 DQWEDICIANSLSDHAGEVDGDGEADADPFADEDSSNGSENDDNEAGASESVESKSGVCVCNKND 479
                                                              ::..|....:.:.:.
Mouse   347 --------------------------------------------------TIRKKKTSQLLHPDS 361

  Fly   480 ALGLEYEVSLQNSLAGAGFLKRNAIFCPTYNDPSYILPNTMERTTQTEPPAVSRLHQMWMCLKSD 544
            ...:...:|||                         .|:.........||.|       |...::
Mouse   362 TRWIPDRISLQ-------------------------APSNYSLLDMRPPPPV-------MITLNN 394

  Fly   545 NSFRKQRERNAAAQ----KSEQGGANCYVN-------------SVSLIDRVARIAFPMSFAFLNL 592
            :.:.::.|.....:    |..|....||..             .||.:|..:|:.||.||...||
Mouse   395 SMYWQEFEDTCVYECLDGKDCQSFFCCYEECKSGSWRRGRIHIDVSELDSYSRVFFPTSFLLFNL 459

  Fly   593 LYWWAY 598
            :||..|
Mouse   460 VYWVGY 465

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8916	NP_573090.3	LIC	92..598	CDD:455710	159/522 (30%)
		LGIC_ECD_GABAR_GRD-like	132..314	CDD:349808	74/181 (41%)
		Cys-loop	233..247	CDD:349808	7/13 (54%)
Gabrg3	XP_017177467.1	LIC	50..465	CDD:455710	156/503 (31%)
		LGIC_ECD_GABAAR_G	71..252	CDD:349801	73/180 (41%)
		Cys-loop	171..185	CDD:349801	7/13 (54%)