Protein Alignment CG8916 and Gabrg2

DIOPT Version :10

• Sequence 1: NP_573090.3
• Gene: CG8916 / 32553
• FlyBaseID: FBgn0030707
• Length: 612
• Species: Drosophila melanogaster
• Sequence 2: NP_032099.1
• Gene: Gabrg2 / 14406
• MGIID: 95623
• Length: 474
• Species: Mus musculus
• Alignment Length: 495
• Identity: 164/495 - (33%)
• Similarity: 246/495 - (49%)
• Gaps: 90/495 - (18%)

  Fly   107 NISMILENLLKRYEQSQLPTHGQGVPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDKRLSF 171
            ::::||.|||:.|:....|..|. .||::.|::.:.|:|||:.::|:|::|.:|.|.|.|:||.|
Mouse    64 DVTVILNNLLEGYDNKLRPDIGV-KPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQTWYDRRLKF 127

  Fly   172 KGPIKSLSLSIKMLDKIWRPDTYFYNGKHSQIHMITVPNKLLRLDQNGGILYSMRLTIKATCPME 236
            ...||.|.|:..|:.|||.|||:|.|.|.:..|.||.||::||:..:|.:||::||||.|.|.::
Mouse   128 NSTIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLRLTIDAECQLQ 192

  Fly   237 LQNFPMDRQSCPLVIGSYGYINQQLIYEWKNQDDAVSFVPGMTLNQFDLISMMHRNFTTVRR--E 299
            |.|||||..||||...||||..::::|:||.....|.......|.||..:.:  ||.|.|.:  .
Mouse   193 LHNFPMDEHSCPLEFSSYGYPREEIVYQWKRSSVEVGDTRSWRLYQFSFVGL--RNTTEVVKTTS 255

  Fly   300 GDFSVLHVAFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREATSDRVSLCVTSVLTLSTISLD 364
            ||:.|:.|.|:|.|..|||.||.|:||.||||||||||||:::|...|.||.:|:|||::|:|..
Mouse   256 GDYVVMSVYFDLSRRMGYFTIQTYIPCTLIVVLSWVSFWINKDAVPARTSLGITTVLTMTTLSTI 320

  Fly   365 SRTDLPKVKYATALDWFLLMSFLYCIATLLEFAGVHYFTKLGSGESPQLE-DQWEDICIANSLSD 428
            :|..||||.|.||:|.|:.:.|::..:.|:|:..:|||.   |...|..: |:.:...:....|.
Mouse   321 ARKSLPKVSYVTAMDLFVSVCFIFVFSALVEYGTLHYFV---SNRKPSKDKDKKKKNPLLRMFSF 382

  Fly   429 HAGEVDGDGEADADPFADEDSSNGSENDDNEAGASESVESKSGVCVCNKNDALGLEYEVSLQNSL 493
            .|            |..|....:.:...:|.....|..|.....|:..|:.|
Mouse   383 KA------------PTIDIRPRSATIQMNNATHLQERDEEYGYECLDGKDCA------------- 422

  Fly   494 AGAGFLKRNAIFCPTYNDPSYILPNTMERTTQTEPPAVSRLHQMWMCLKSDNSFRKQRERNAAAQ 558
                     :.|| .:.|            .:|......|:|
Mouse   423 ---------SFFC-CFED------------CRTGAWRHGRIH----------------------- 442

  Fly   559 KSEQGGANCYVNSVSLIDRVARIAFPMSFAFLNLLYWWAY 598
                       ..::.:|..|||.||.:|...||:||.:|
Mouse   443 -----------IRIAKMDSYARIFFPTAFCLFNLVYWVSY 471

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8916	NP_573090.3	LIC	92..598	CDD:455710	163/493 (33%)
		LGIC_ECD_GABAR_GRD-like	132..314	CDD:349808	78/183 (43%)
		Cys-loop	233..247	CDD:349808	7/13 (54%)
Gabrg2	NP_032099.1	LIC	68..471	CDD:455710	163/489 (33%)
		LGIC_ECD_GABAAR_G	89..270	CDD:349801	77/182 (42%)
		Cys-loop	189..203	CDD:349801	7/13 (54%)