Protein Alignment CG8916 and Gabrg2

DIOPT Version :9

• Sequence 1: NP_573090.3
• Gene: CG8916 / 32553
• FlyBaseID: FBgn0030707
• Length: 612
• Species: Drosophila melanogaster
• Sequence 2: NP_032099.1
• Gene: Gabrg2 / 14406
• MGIID: 95623
• Length: 474
• Species: Mus musculus
• Alignment Length: 495
• Identity: 164/495 - (33%)
• Similarity: 246/495 - (49%)
• Gaps: 90/495 - (18%)

  Fly   107 NISMILENLLKRYEQSQLPTHGQGVPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDKRLSF 171
            ::::||.|||:.|:....|..|. .||::.|::.:.|:|||:.::|:|::|.:|.|.|.|:||.|
Mouse    64 DVTVILNNLLEGYDNKLRPDIGV-KPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQTWYDRRLKF 127

  Fly   172 KGPIKSLSLSIKMLDKIWRPDTYFYNGKHSQIHMITVPNKLLRLDQNGGILYSMRLTIKATCPME 236
            ...||.|.|:..|:.|||.|||:|.|.|.:..|.||.||::||:..:|.:||::||||.|.|.::
Mouse   128 NSTIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLRLTIDAECQLQ 192

  Fly   237 LQNFPMDRQSCPLVIGSYGYINQQLIYEWKNQDDAVSFVPGMTLNQFDLISMMHRNFTTVRR--E 299
            |.|||||..||||...||||..::::|:||.....|.......|.||..:.:  ||.|.|.:  .
Mouse   193 LHNFPMDEHSCPLEFSSYGYPREEIVYQWKRSSVEVGDTRSWRLYQFSFVGL--RNTTEVVKTTS 255

  Fly   300 GDFSVLHVAFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREATSDRVSLCVTSVLTLSTISLD 364
            ||:.|:.|.|:|.|..|||.||.|:||.||||||||||||:::|...|.||.:|:|||::|:|..
Mouse   256 GDYVVMSVYFDLSRRMGYFTIQTYIPCTLIVVLSWVSFWINKDAVPARTSLGITTVLTMTTLSTI 320

  Fly   365 SRTDLPKVKYATALDWFLLMSFLYCIATLLEFAGVHYFTKLGSGESPQLE-DQWEDICIANSLSD 428
            :|..||||.|.||:|.|:.:.|::..:.|:|:..:|||.   |...|..: |:.:...:....|.
Mouse   321 ARKSLPKVSYVTAMDLFVSVCFIFVFSALVEYGTLHYFV---SNRKPSKDKDKKKKNPLLRMFSF 382

  Fly   429 HAGEVDGDGEADADPFADEDSSNGSENDDNEAGASESVESKSGVCVCNKNDALGLEYEVSLQNSL 493
            .|            |..|....:.:...:|.....|..|.....|:..|:.|
Mouse   383 KA------------PTIDIRPRSATIQMNNATHLQERDEEYGYECLDGKDCA------------- 422

  Fly   494 AGAGFLKRNAIFCPTYNDPSYILPNTMERTTQTEPPAVSRLHQMWMCLKSDNSFRKQRERNAAAQ 558
                     :.|| .:.|            .:|......|:|
Mouse   423 ---------SFFC-CFED------------CRTGAWRHGRIH----------------------- 442

  Fly   559 KSEQGGANCYVNSVSLIDRVARIAFPMSFAFLNLLYWWAY 598
                       ..::.:|..|||.||.:|...||:||.:|
Mouse   443 -----------IRIAKMDSYARIFFPTAFCLFNLVYWVSY 471

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8916	NP_573090.3	LIC	92..598	CDD:273305	163/493 (33%)
		Neur_chan_LBD	111..315	CDD:280998	87/205 (42%)
		Neur_chan_memb	322..>403	CDD:280999	40/80 (50%)
Gabrg2	NP_032099.1	LIC	68..471	CDD:273305	163/489 (33%)
		Neur_chan_LBD	68..271	CDD:280998	87/205 (42%)
		Neur_chan_memb	278..468	CDD:280999	69/273 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	199	1.000	Domainoid score	I3055
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1057372at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm43906
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR18945
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3154
SonicParanoid	1	1.000	-	-		X127
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	10	9.950