Protein Alignment CG8916 and Gabrg1

DIOPT Version :10

• Sequence 1: NP_573090.3
• Gene: CG8916 / 32553
• FlyBaseID: FBgn0030707
• Length: 612
• Species: Drosophila melanogaster
• Sequence 2: NP_034382.2
• Gene: Gabrg1 / 14405
• MGIID: 103156
• Length: 465
• Species: Mus musculus
• Alignment Length: 499
• Identity: 167/499 - (33%)
• Similarity: 243/499 - (48%)
• Gaps: 106/499 - (21%)

  Fly   107 NISMILENLLKRYEQSQLPTHGQGVPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDKRLSF 171
            :|:.||.:||:.|:....|..|.. |||::|::.:.|:|||..::|:|::|..|.|.|.|.||.|
Mouse    63 DITQILNSLLQGYDNKLRPDIGVR-PTVIETDVYVNSIGPVDPINMEYTIDIIFAQTWFDSRLKF 126

  Fly   172 KGPIKSLSLSIKMLDKIWRPDTYFYNGKHSQIHMITVPNKLLRLDQNGGILYSMRLTIKATCPME 236
            ...:|.|.|:..|:.|||.|||:|.|.:.|..|.||.||:|||:..:|.:||::||||.|.|.::
Mouse   127 NSTMKVLMLNSNMVGKIWIPDTFFRNSRKSDAHWITTPNRLLRIWSDGRVLYTLRLTINAECYLQ 191

  Fly   237 LQNFPMDRQSCPLVIGSYGYINQQLIYEWKNQDDAVSFVPGMTLNQFDLISMMHRNFTTVRR--E 299
            |.|||||..||||...||||...::.|:||.....|:......|.||..:.:  ||.|.:..  .
Mouse   192 LHNFPMDEHSCPLEFSSYGYPKNEIEYKWKKPSVEVADPKYWRLYQFAFVGL--RNSTEISHTIS 254

  Fly   300 GDFSVLHVAFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREATSDRVSLCVTSVLTLSTISLD 364
            ||:.::.:.|:|.|..|||.||.|:||||.||||||||||:::|...|.||.:|:|||::|:|..
Mouse   255 GDYIIMTIFFDLSRRMGYFTIQTYIPCILTVVLSWVSFWINKDAVPARTSLGITTVLTMTTLSTI 319

  Fly   365 SRTDLPKVKYATALDWFLLMSFLYCIATLLEFAGVHYFTKLGSGESPQLEDQWEDICIANSLSDH 429
            :|..||||.|.||:|.|:.:.|::..|.|:|:..:||||....|::.:
Mouse   320 ARKSLPKVSYVTAMDLFVSVCFIFVFAALMEYGTLHYFTSNNKGKTTR----------------- 367

  Fly   430 AGEVDGDGEADADPFADEDSSNGSENDDNEAGASESVESKSGVCVCNKNDAL-GLEYEVSLQNSL 493
                                                     |..:.||..|. ||.
Mouse   368 -----------------------------------------GRKLKNKTSASPGLH--------- 382

  Fly   494 AGAGFLKRNAIFCPT-YNDPSYILPNTMERTTQTEPPAVSRLHQMWMCLKSD---NSFRKQRERN 554
            ||:..:..|:|..|. .:|..|......:.|:             :.|...|   .|:|:.|...
Mouse   383 AGSTLIPMNSISLPQGEDDYGYQCLEGKDCTS-------------FFCCFDDCRTGSWREGRIHI 434

  Fly   555 AAAQKSEQGGANCYVNSVSLIDRVARIAFPMSFAFLNLLYWWAY 598
            ..|:                ||..:||.||.:||..||:||..|
Mouse   435 RIAK----------------IDSYSRIFFPTAFALFNLVYWVGY 462

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8916	NP_573090.3	LIC	92..598	CDD:455710	166/497 (33%)
		LGIC_ECD_GABAR_GRD-like	132..314	CDD:349808	76/183 (42%)
		Cys-loop	233..247	CDD:349808	7/13 (54%)
Gabrg1	NP_034382.2	LIC	66..462	CDD:455710	165/494 (33%)
		LGIC_ECD_GABAAR_G	88..269	CDD:349801	75/182 (41%)
		Cys-loop	188..202	CDD:349801	7/13 (54%)