Protein Alignment CG8916 and Gabra3

DIOPT Version :9

• Sequence 1: NP_573090.3
• Gene: CG8916 / 32553
• FlyBaseID: FBgn0030707
• Length: 612
• Species: Drosophila melanogaster
• Sequence 2: NP_001344745.1
• Gene: Gabra3 / 14396
• MGIID: 95615
• Length: 523
• Species: Mus musculus
• Alignment Length: 616
• Identity: 202/616 - (32%)
• Similarity: 301/616 - (48%)
• Gaps: 145/616 - (23%)

  Fly    10 IIIGFMAHFCACEDVTSSDLLYIKTMGPSAILTKMPNITNEFSSRIFSSFRILPSSKPKTN-GSL 73
            :||..|.||            |:..:....:::.:|..|::..||     |..|....|.: |.|
Mouse    32 MIITQMWHF------------YVTRVVLLLLISILPGTTSQGESR-----RQEPGDFVKQDIGGL 79

  Fly    74 KRSQNATNLSYSSSEISNQRRVRRKAAADMLSRNISM---ILENLLKRYEQSQLPTHGQGVPTVV 135
            . .::|.::...|::                  ||::   ||:.||..|:....|..|..| |.|
Mouse    80 S-PKHAPDIPDDSTD------------------NITIFTRILDRLLDGYDNRLRPGLGDAV-TEV 124

  Fly   136 QTNILIRSMGPVSELDMDYSMDCYFRQYWRDKRLSFKGPIKSLSLSIKMLDKIWRPDTYFYNGKH 200
            :|:|.:.|.||||:.||:|::|.:|||.|.|:||.|.||:|.|.|:..:..|||.|||:|:|||.
Mouse   125 KTDIYVTSFGPVSDTDMEYTIDVFFRQTWHDERLKFDGPMKILPLNNLLASKIWTPDTFFHNGKK 189

  Fly   201 SQIHMITVPNKLLRLDQNGGILYSMRLTIKATCPMELQNFPMDRQSCPLVIGSYGYINQQLIYEW 265
            |..|.:|.|||||||..||.:||:|||||.|.|||.|::||||..:|||..|||.|...::||.|
Mouse   190 SVAHNMTTPNKLLRLVDNGTLLYTMRLTIHAECPMHLEDFPMDVHACPLKFGSYAYTKAEVIYSW 254

  Fly   266 ---KNQDDAVSFVPGMTLNQFDLISMMHRNFTTVRRE--GDFSVLHVAFNLKRHTGYFLIQVYVP 325
               ||:...|: ..|..|||:||:.  |...|.:.|.  |::.|:...|:|||..|||:||.|:|
Mouse   255 TLGKNKSVEVA-QDGSRLNQYDLLG--HVVGTEIIRSSTGEYVVMTTHFHLKRKIGYFVIQTYLP 316

  Fly   326 CILIVVLSWVSFWIHREATSDRVSLCVTSVLTLSTISLDSRTDLPKVKYATALDWFLLMSFLYCI 390
            ||:.|:||.||||::||:...|....||:|||::|:|:.:|..||||.||||:|||:.:.:.:..
Mouse   317 CIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVF 381

  Fly   391 ATLLEFAGVHYFTKLGSGESPQLEDQWEDICIANSLSDHAGEVDGDGEADADPFADEDSSNGSEN 455
            :.|:|||.|:||||....        ||...:..:|
Mouse   382 SALIEFATVNYFTKRSWA--------WEGKKVPEAL----------------------------- 409

  Fly   456 DDNEAGASESVESKSGVCVCNKN---DALGLEYEVSLQNSLAGAGFLKRNAIFCPTYND-PSYIL 516
                     .::.|:......||   :.:|..|.::|......:...|..|  .|:.:. |:.|.
Mouse   410 ---------EMKKKTPAAPTKKNTTFNIVGTTYPINLAKDTEFSTISKSAA--APSASSTPTAIA 463

  Fly   517 PNTMERTTQTEPPAVSRLHQMWMCLKSDNSFRKQRERNAAAQKSEQGGANCYVNSVSLIDRVARI 581
              :.:.|...:.||.::.:                                  ||||.:|:::||
Mouse   464 --SPKATYVQDSPAETKTY----------------------------------NSVSKVDKISRI 492

  Fly   582 AFPMSFAFLNLLYWWAY--------GMYKKE 604
            .||:.||..||:||..|        ||.:|:
Mouse   493 IFPVLFAIFNLVYWATYVNRESAIKGMIRKQ 523

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8916	NP_573090.3	LIC	92..598	CDD:273305	181/517 (35%)
		Neur_chan_LBD	111..315	CDD:280998	100/208 (48%)
		Neur_chan_memb	322..>403	CDD:280999	39/80 (49%)
Gabra3	NP_001344745.1	Neur_chan_LBD	100..509	CDD:332142	179/496 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	199	1.000	Domainoid score	I3055
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1057372at2759
OrthoFinder	1	1.000	-	-		FOG0000415
OrthoInspector	1	1.000	-	-		otm43906
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR18945
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X127
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	7.920