Protein Alignment CG8916 and LOC1270594

DIOPT Version :10

• Sequence 1: NP_573090.3
• Gene: CG8916 / 32553
• FlyBaseID: FBgn0030707
• Length: 612
• Species: Drosophila melanogaster
• Sequence 2: XP_061518959.1
• Gene: LOC1270594 / 1270594
• VectorBaseID: AGAMI1_011195
• Length: 655
• Species: Anopheles gambiae
• Alignment Length: 600
• Identity: 233/600 - (38%)
• Similarity: 315/600 - (52%)
• Gaps: 127/600 - (21%)

  Fly   107 NISMILENLLKRYEQSQLPTHGQGVPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDKRLSF 171
            |||.:|:|||:.|:.|..|..| |.|.|::.:|::|||||:||:||.|||||||||.|.|:||:|
Mosquito    61 NISELLDNLLRGYDNSIRPDFG-GPPAVIEVDIMVRSMGPISEVDMTYSMDCYFRQSWVDRRLAF 124

  Fly   172 KGPIKSLSLSIKMLDKIWRPDTYFYNGKHSQIHMITVPNKLLRLDQNGGILYSMRLTIKATCPME 236
            .|...:|:|||.||.:||:|||||||||.|.:|.||.|||.:||.|:|.:|||.||||||.|||.
Mosquito   125 SGAQDTLALSISMLGRIWKPDTYFYNGKQSYLHTITTPNKFVRLYQDGRVLYSSRLTIKAGCPMN 189

  Fly   237 LQNFPMDRQSCPLVIGSYGYINQQLIYEWKNQDDAVSFVPGMTLNQFDLISMMHRNFT------- 294
            |::||||.|.|||..||:||....::|.|.:...||:....|.|:||||:.....|.|
Mosquito   190 LEDFPMDTQRCPLKFGSFGYTTNDVLYRWNSGRTAVTIADDMKLSQFDLVEWPAGNVTDRVVHNT 254

  Fly   295 -----TVRR-----------------------EG-------DFSVLHVAFNLKRHTGYFLIQVYV 324
                 ||..                       ||       ::|:|.|:|:|:||.|.||||||.
Mosquito   255 ASAGATVLNGMGNADLELGLGLDGGVGRATGGEGNGKLYMSEYSMLLVSFHLQRHMGNFLIQVYG 319

  Fly   325 PCILIVVLSWVSFWIHREATSDRVSLCVTSVLTLSTISLDSRTDLPKVKYATALDWFLLMSFLYC 389
            ||:|:|||||||||::||||:|||||.:|:|||::.:.|::|||||||.|.||||:|:.:||.:.
Mosquito   320 PCVLLVVLSWVSFWLNREATADRVSLGITTVLTMTFLGLEARTDLPKVPYPTALDFFVFLSFGFI 384

  Fly   390 IATLLEFAGVHYFTKLGSGESPQLEDQWEDICIANSLSDHAGEVDGDGEADADPFADEDSSNGSE 454
            .||:::||.||||||.||||.....|:      ..|.||     |.|.:.:|.......||..::
Mosquito   385 FATIIQFAIVHYFTKYGSGECYFSVDE------LTSSSD-----DEDSDREAPDRNGPGSSRAAQ 438

  Fly   455 NDD--NEAGAS-----------ESVESKSGVCVCNKNDALGLEY--------------------- 485
            :..  |.||.:           .::.|.||.......|:..:|.
Mosquito   439 HHHSINIAGPAGTPGRCGGKRCSTITSISGAQGSGATDSRIIEVIPLSVCSFPLTPMRKTPKTSW 503

  Fly   486 -EVSLQNSLAGAGFLKRNAIFCPTYNDPSYILPNTMER-----------TTQT---EPPAVSRL- 534
             :||.....:..|      :...|.:|| :...:|:||           ||.:   .||..|.|
Mosquito   504 TDVSCFGGGSSCG------VEDSTTSDP-HASTSTVERAGAYGAPIETATTSSSFASPPTTSALG 561

  Fly   535 --HQMWMCLKSDNSFRKQRER---NAAAQKSEQGGANCY-----------VNSVSLIDRVARIAF 583
              |:.............|:..   ||....||..|.|.:           .||||.|||.:||.|
Mosquito   562 GHHRRRSGAAGSTHGGVQQHHLTINAPLTASETHGTNGHRTRRRRKRAPRFNSVSKIDRASRIFF 626

  Fly   584 PMSFAFLNLLYWWAY 598
            |:.|..:|:.||:.|
Mosquito   627 PLLFLAINVFYWYLY 641

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8916	NP_573090.3	LIC	92..598	CDD:455710	232/598 (39%)
		LGIC_ECD_GABAR_GRD-like	132..314	CDD:349808	101/223 (45%)
		Cys-loop	233..247	CDD:349808	9/13 (69%)
LOC1270594	XP_061518959.1	None