Protein Alignment CG8916 and Glra3

DIOPT Version :10

• Sequence 1: NP_573090.3
• Gene: CG8916 / 32553
• FlyBaseID: FBgn0030707
• Length: 612
• Species: Drosophila melanogaster
• Sequence 2: NP_536686.3
• Gene: Glra3 / 110304
• MGIID: 95749
• Length: 464
• Species: Mus musculus
• Alignment Length: 536
• Identity: 169/536 - (31%)
• Similarity: 259/536 - (48%)
• Gaps: 114/536 - (21%)

  Fly    82 LSYSSSEISNQRRVRRKAAADMLSRNISMILENLLKR---YEQSQLPTHGQGVPTVVQTNILIRS 143
            ||..:::.:|..|.|   :|.|   :.|..|:.|:.|   |: :::..:.:|.|..|..||.|.|
Mouse    23 LSLVATKETNSARSR---SAPM---SPSDFLDKLMGRTSGYD-ARIRPNFKGPPVNVTCNIFINS 80

  Fly   144 MGPVSELDMDYSMDCYFRQYWRDKRLSF-KGPIKSLSLSIKMLDKIWRPDTYFYNGKHSQIHMIT 207
            .|.::|..|||.::.:.||.|.|.||:: :.|..||.|...|||.||:||.:|.|.|.:..|.:|
Mouse    81 FGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVT 145

  Fly   208 VPNKLLRLDQNGGILYSMRLTIKATCPMELQNFPMDRQSCPLVIGSYGYINQQLIYEWKNQDDA- 271
            ..|||||:.:||.:|||:|||:..:|||:|:|||||.|:|.:.:.|:||....||:||  ||:|
Mouse   146 TDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEW--QDEAP 208

  Fly   272 VSFVPGMTLNQFDLISMMHRNFTTVR-REGDFSVLHVAFNLKRHTGYFLIQVYVPCILIVVLSWV 335
            |....|:||.||.|.......:.|.. ..|.|:.:.|.|:|:|..||:|||:|:|.:|||:||||
Mouse   209 VQVAEGLTLPQFLLKEEKDLRYCTKHYNTGKFTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWV 273

  Fly   336 SFWIHREATSDRVSLCVTSVLTLSTISLDSRTDLPKVKYATALDWFLLMSFLYCIATLLEFAGVH 400
            ||||:.:|...||:|.:|:|||::|.|..||..||||.|..|:|.::.:..|:..:.|||:|.|:
Mouse   274 SFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVN 338

  Fly   401 YFTKLGSGESPQLEDQWEDICIANSLSDHAGEVDGDGEADADPFADEDSSNGSENDDNEAGASES 465
            :.::           |.:::........:..|.          ||.|.....|:.||      |.
Mouse   339 FVSR-----------QHKELLRFRRKRKNKTEA----------FALEKFYRFSDTDD------EV 376

  Fly   466 VESK-------SGVCVCNKNDALGLEYEVSLQNSLAGAGFLKRNAIFCPTYNDPSYILPNTMERT 523
            .||:       .|.|:..|:.                                   ::|......
Mouse   377 RESRFSFTAYGMGPCLQAKDG-----------------------------------VVPKGPNHA 406

  Fly   524 TQTEPPAVSRLHQMWMCLKSDNSFRKQRERNAAAQKSEQGGANCYVNSVSLIDRVARIAFPMSFA 588
            .|..|             ||.:..||                 .:::....||.::|..||::|.
Mouse   407 VQVMP-------------KSPDEMRK-----------------VFIDRAKKIDTISRACFPLAFL 441

  Fly   589 FLNLLYWWAYGMYKKE 604
            ..|:.||..|.:.:.|
Mouse   442 IFNIFYWVIYKILRHE 457

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8916	NP_573090.3	LIC	92..598	CDD:455710	164/518 (32%)
		LGIC_ECD_GABAR_GRD-like	132..314	CDD:349808	80/184 (43%)
		Cys-loop	233..247	CDD:349808	10/13 (77%)
Glra3	NP_536686.3	LIC	12..451	CDD:273305	167/528 (32%)