Protein Alignment CG8916 and gabra3

DIOPT Version :10

• Sequence 1: NP_573090.3
• Gene: CG8916 / 32553
• FlyBaseID: FBgn0030707
• Length: 612
• Species: Drosophila melanogaster
• Sequence 2: XP_073791639.1
• Gene: gabra3 / 100538116
• ZFINID: ZDB-GENE-091204-365
• Length: 488
• Species: Danio rerio
• Alignment Length: 510
• Identity: 187/510 - (36%)
• Similarity: 266/510 - (52%)
• Gaps: 91/510 - (17%)

  Fly    97 RKAAADMLSRNISM---ILENLLKRYEQSQLPTHGQGVPTVVQTNILIRSMGPVSELDMDYSMDC 158
            |:...|....||::   ||:.||..|:....|..|....|.|:|||.:.|.||||:.||:|::|.
Zfish    48 REPIPDDSKDNITIFTRILDRLLDGYDNRLRPGLGAESVTEVRTNIYVTSFGPVSDTDMEYTIDV 112

  Fly   159 YFRQYWRDKRLSFKGPIKSLSLSIKMLDKIWRPDTYFYNGKHSQIHMITVPNKLLRLDQNGGILY 223
            :|||.|||:||.|.||::.|.|:..:..|||.|||:|:|||.|..|.:|.|||||||..||.:||
Zfish   113 FFRQSWRDERLKFDGPMQVLPLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRLVDNGTLLY 177

  Fly   224 SMRLTIKATCPMELQNFPMDRQSCPLVIGSYGYINQQLIYEWKNQDD-AVSFVP-GMTLNQFDLI 286
            :|||||.|.|||.|::||||..:|||..|||.|.|.:::|.|...|: :||..| |..|||:||:
Zfish   178 TMRLTIHAECPMHLEDFPMDAHACPLKFGSYAYTNNEVVYIWTADDEKSVSVAPDGSRLNQYDLL 242

  Fly   287 SMMHRNFTTVRREGDFSVLHVAFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREATSDRVSLC 351
            ..:....|.....|::.|:...|:|||..|||:||.|:|||:.|:||.||||::||:...|....
Zfish   243 GHVIGKETISSSTGEYVVMTTYFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFG 307

  Fly   352 VTSVLTLSTISLDSRTDLPKVKYATALDWFLLMSFLYCIATLLEFAGVHYFTKLGSGESPQLEDQ 416
            ||:|||::|:|:.:|..||||.||||:|||:.:.:.:..:.|:|||.|:||||          ..
Zfish   308 VTTVLTMTTLSISARNSLPKVAYATAMDWFMAVCYAFVFSALIEFATVNYFTK----------RS 362

  Fly   417 WEDICIANSLSDHAGEVDGDGEADADPFADEDSSNGSENDDNEAGASESVESKSGVCVCNKNDAL 481
            |.                .||:.:|......:|::.|:..:|..                  :.:
Zfish   363 WA----------------WDGQKEAQEMRRRESASFSKKTNNTF------------------NIV 393

  Fly   482 GLEYEVSLQNSLAGAGFLKRNAIFCPTYNDPSY-ILPNTMERTTQTEPPAVS--RLHQMWMCLKS 543
            |..|.:|:                   ..||.. .:..:...||.|.|..|.  ||.:|
Zfish   394 GTTYSMSV-------------------VKDPGLTTISKSATPTTSTPPQPVREVRLPKM------ 433

  Fly   544 DNSFRKQRERNAAAQKSEQGGANCYVNSVSLIDRVARIAFPMSFAFLNLLYWWAY 598
            |..:..:             |...| |.||.:|:::||.||:.|...||.||..|
Zfish   434 DGEYVPE-------------GRKSY-NRVSKVDKISRIIFPVLFFIFNLGYWATY 474

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8916	NP_573090.3	LIC	92..598	CDD:455710	186/508 (37%)
		LGIC_ECD_GABAR_GRD-like	132..314	CDD:349808	91/183 (50%)
		Cys-loop	233..247	CDD:349808	8/13 (62%)
gabra3	XP_073791639.1	None