Protein Alignment CG8916 and gabra3

DIOPT Version :10

• Sequence 1: NP_573090.3
• Gene: CG8916 / 32553
• FlyBaseID: FBgn0030707
• Length: 612
• Species: Drosophila melanogaster
• Sequence 2: XP_002939243.2
• Gene: gabra3 / 100494398
• XenbaseID: XB-GENE-992774
• Length: 538
• Species: Xenopus tropicalis
• Alignment Length: 501
• Identity: 183/501 - (36%)
• Similarity: 262/501 - (52%)
• Gaps: 99/501 - (19%)

  Fly   107 NISM---ILENLLKRYEQSQLPTHGQGVPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDKR 168
            ||::   ||:.||..|:....|..|..| |.|:|:|.:.|.||||:.||:|::|.:|||.|.|:|
 Frog   115 NITIFTRILDRLLDGYDNRLRPGLGDSV-TEVKTDIYVTSFGPVSDTDMEYTIDVFFRQSWLDER 178

  Fly   169 LSFKGPIKSLSLSIKMLDKIWRPDTYFYNGKHSQIHMITVPNKLLRLDQNGGILYSMRLTIKATC 233
            |.|.|||::|.|:..:..|||.|||:|:|||.|..|.:|.|||||||..||.:||:|||||.|.|
 Frog   179 LKFDGPIRTLPLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRLIDNGTLLYTMRLTIHAEC 243

  Fly   234 PMELQNFPMDRQSCPLVIGSYGYINQQLIYEWKN-QDDAVSFVP-GMTLNQFDLISMMHRNFTTV 296
            .|.|::||||..:|||..|||.|...:::|.|.| .:.:|:..| |..|||:||:.:.....|..
 Frog   244 TMHLEDFPMDVHACPLKFGSYAYPKTEVVYSWTNGSNKSVAVAPDGSRLNQYDLLGVAVGTETIR 308

  Fly   297 RREGDFSVLHVAFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREATSDRVSLCVTSVLTLSTI 361
            ...|::.|:...|:|||..|||:||.|:|||:.|:||.||||::||:...|....||:|||::|:
 Frog   309 SSTGEYIVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTL 373

  Fly   362 SLDSRTDLPKVKYATALDWFLLMSFLYCIATLLEFAGVHYFTKLGSGESPQLEDQWEDICIANSL 426
            |:.:|..||||.||||:|||:.:.:.:..:.|:|||.|:||||.|..        |
 Frog   374 SISARNSLPKVAYATAMDWFMAVCYAFVFSALIEFATVNYFTKRGWA--------W--------- 421

  Fly   427 SDHAGEVDGDGEADADPFADEDSSNGSENDDNEAGASESVESKSGVCVCNKNDA----LGLEYEV 487
                                 |...|.|..|        .:.|..:.:..|::.    :|..|.:
 Frog   422 ---------------------DGKRGQEGQD--------FKKKEPIILAKKSNTTYNIVGTTYTL 457

  Fly   488 SLQNSLAGAGFLKRNAIFCPTYNDPSYILPNTMERTTQTEPPAVSRLHQMWMCLKSDNSFRKQRE 552
            :::.. |.|...|..|:..|    |..:.|..:|             |:...|.|:
 Frog   458 NIKEP-ALATIAKSAALQPP----PPPLSPRHLE-------------HKPMECKKT--------- 495

  Fly   553 RNAAAQKSEQGGANCYVNSVSLIDRVARIAFPMSFAFLNLLYWWAY 598
                            .||||.||:::||.||:.||..||:||..|
 Frog   496 ----------------YNSVSRIDKISRIVFPVLFAIFNLVYWATY 525

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8916	NP_573090.3	LIC	92..598	CDD:455710	182/499 (36%)
		LGIC_ECD_GABAR_GRD-like	132..314	CDD:349808	87/183 (48%)
		Cys-loop	233..247	CDD:349808	7/13 (54%)
gabra3	XP_002939243.2	LIC	121..525	CDD:455710	180/493 (37%)
		LGIC_ECD_GABAAR_A3	127..326	CDD:349837	92/199 (46%)
		Cys-loop	243..257	CDD:349837	7/13 (54%)