Protein Alignment CG8916 and glra2

DIOPT Version :10

• Sequence 1: NP_573090.3
• Gene: CG8916 / 32553
• FlyBaseID: FBgn0030707
• Length: 612
• Species: Drosophila melanogaster
• Sequence 2: XP_004912302.1
• Gene: glra2 / 100494348
• XenbaseID: XB-GENE-958032
• Length: 488
• Species: Xenopus tropicalis
• Alignment Length: 523
• Identity: 161/523 - (30%)
• Similarity: 253/523 - (48%)
• Gaps: 109/523 - (20%)

  Fly   109 SMILENLLKR---YEQSQLPTHGQGVPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDKRLS 170
            |..|:.|:.|   |: :::..:.:|.|..|..||.|.|.|.::|..|||.::.:.||.|.|.|||
 Frog    43 SDFLDKLMGRTSGYD-ARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQTWNDPRLS 106

  Fly   171 F-KGPIKSLSLSIKMLDKIWRPDTYFYNGKHSQIHMITVPNKLLRLDQNGGILYSMRLTIKATCP 234
            : :.|..||.|...|||.||:||.:|.|.|.:..|.:|..|||||:.:||.:|||:|||:..:||
 Frog   107 YSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRIFKNGNVLYSIRLTLTLSCP 171

  Fly   235 MELQNFPMDRQSCPLVIGSYGYINQQLIYEWKNQDDAVSFVPGMTLNQFDL-----ISMMHRNFT 294
            |:|:|||||.|:|.:.:.|:||....||:||.: ...|....|:||.||.|     :....:::.
 Frog   172 MDLKNFPMDVQTCAMQLESFGYTMNDLIFEWLS-TSPVQVADGLTLPQFILKEENELGYCTKHYN 235

  Fly   295 TVRREGDFSVLHVAFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREATSDRVSLCVTSVLTLS 359
            |    |.|:.:.|.|:|:|..||:|||:|:|.:|||:||||||||:.:|...||:|.:|:|||::
 Frog   236 T----GKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMT 296

  Fly   360 TISLDSRTDLPKVKYATALDWFLLMSFLYCIATLLEFAGVHY-------FTKLGSGESPQLEDQW 417
            |.|..||..||||.|..|:|.::.:..|:..|.|||:|.|::       |.:|...:    :.|.
 Frog   297 TQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSRQHKEFLRLRRRQ----KRQS 357

  Fly   418 EDICIANSLSDHAGEVDGDGEADADPFA-----------DEDSSNGSENDDNEAGASESVESKSG 471
            :.:.:.|...:....::|....|:..:.           :||.:..|..:.:..|....::.|.|
 Frog   358 KTVLVGNESVESVRRMNGLRSTDSSAYGTLNQIYNPSLREEDVARESRFNFSGYGMGHCLQVKDG 422

  Fly   472 VCVCNKNDALGLEYEVSLQNSLAGAGFLKRNAIFCPTYNDPSYILPNTMERTTQTEPPAVSRLHQ 536
            ..|                                               :.|...||....
 Frog   423 TAV-----------------------------------------------KATPPIPPPPQP--- 437

  Fly   537 MWMCLKSDNSFRKQRERNAAAQKSEQGGANCYVNSVSLIDRVARIAFPMSFAFLNLLYWWAYGMY 601
                 |..:|.:|:                 :|:....||.::|.|||::|...|:.||..|.:.
 Frog   438 -----KDADSIKKK-----------------FVDRAKRIDTISRAAFPLAFLIFNIFYWITYKII 480

  Fly   602 KKE 604
            :.|
 Frog   481 RHE 483

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8916	NP_573090.3	LIC	92..598	CDD:455710	159/515 (31%)
		LGIC_ECD_GABAR_GRD-like	132..314	CDD:349808	78/187 (42%)
		Cys-loop	233..247	CDD:349808	10/13 (77%)
glra2	XP_004912302.1	LIC	44..477	CDD:273305	158/514 (31%)