Protein Alignment CG8916 and gabra5

DIOPT Version :9

• Sequence 1: NP_573090.3
• Gene: CG8916 / 32553
• FlyBaseID: FBgn0030707
• Length: 612
• Species: Drosophila melanogaster
• Sequence 2: XP_004911866.1
• Gene: gabra5 / 100494208
• XenbaseID: XB-GENE-980292
• Length: 475
• Species: Xenopus tropicalis
• Alignment Length: 530
• Identity: 184/530 - (34%)
• Similarity: 272/530 - (51%)
• Gaps: 116/530 - (21%)

  Fly    79 ATNLSYSSSEISNQRRVRRKAAADMLSRNISM---ILENLLKRYEQSQLPTHGQGVPTVVQTNIL 140
            |||.|.|.:..:        ...:..:.||::   ||:.||..|:....|..|:.: |.|:|:|.
 Frog    29 ATNFSMSQTTAA--------PVKEDTNDNITIFTRILDGLLDGYDNRLRPGLGERI-TQVKTDIY 84

  Fly   141 IRSMGPVSELDMDYSMDCYFRQYWRDKRLSFKGPIKSLSLSIKMLDKIWRPDTYFYNGKHSQIHM 205
            :.|.||||:.:|:|::|.:|||.|:|:||.|:||:..|.|:..:..|||.|||:|:|||.|..|.
 Frog    85 VTSFGPVSDTEMEYTIDVFFRQSWKDERLCFQGPMPRLPLNNLLASKIWTPDTFFHNGKKSIAHN 149

  Fly   206 ITVPNKLLRLDQNGGILYSMRLTIKATCPMELQNFPMDRQSCPLVIGSYGYINQQLIYEWKNQDD 270
            ||.|||||||:.:|.:||:|||||.|.|||:|::||||..:|||..|||.|.|.:|.|||.|..|
 Frog   150 ITTPNKLLRLEDDGTLLYTMRLTISAECPMQLEDFPMDAHACPLKFGSYAYPNSELRYEWTNITD 214

  Fly   271 --AVSFVPGMTLNQFDLI--SMMHRNFTTVRREGDFSVLHVAFNLKRHTGYFLIQVYVPCILIVV 331
              .|....|..|||:.||  ::...|.:|  ..|:::|:...|:|||..|||:||.|:|||:.|:
 Frog   215 KSVVVAEDGSRLNQYHLIGQTVGTENIST--STGEYTVMTAHFHLKRKIGYFVIQTYLPCIMTVI 277

  Fly   332 LSWVSFWIHREATSDRVSLCVTSVLTLSTISLDSRTDLPKVKYATALDWFLLMSFLYCIATLLEF 396
            ||.||||::||:...|....||:|||::|:|:.:|..||||.||||:|||:.:.:.:..:.|:||
 Frog   278 LSQVSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEF 342

  Fly   397 AGVHYFTKLGSGESPQLEDQWEDICIANSLSDHAGEVDGDGEADADPFADEDSSNGSENDDNEAG 461
            |.|:||||....        |                ||....:|...         :..:.|:.
 Frog   343 ATVNYFTKRSWA--------W----------------DGKKALEAAKI---------KKKEQESL 374

  Fly   462 ASESVESKSGVCVCNKNDALGLEYEVSLQNSLAGAGFLKRNAIFCPTYNDPSYILPNTME---RT 523
            ..:.:.|.||          .:.|..::...|.                  |.::.|...   :|
 Frog   375 GRKPINSYSG----------RIPYTPNMSKDLT------------------SSVIANAASIHMKT 411

  Fly   524 TQTEPPAVSRLHQMWMCLKSDNSFRKQRERNAAAQKSEQGGANCYVNSVSLIDRVARIAFPMSFA 588
            |:.:            |.:|..::                      ||||.||:::||.||:.|.
 Frog   412 TEEK------------CAESKKTY----------------------NSVSKIDKMSRIVFPVMFG 442

  Fly   589 FLNLLYWWAY 598
            ..||:||..|
 Frog   443 TFNLVYWATY 452

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8916	NP_573090.3	LIC	92..598	CDD:273305	178/515 (35%)
		Neur_chan_LBD	111..315	CDD:280998	98/207 (47%)
		Neur_chan_memb	322..>403	CDD:280999	39/80 (49%)
gabra5	XP_004911866.1	LIC	25..452	CDD:273305	183/528 (35%)
		LGIC_ECD_GABAAR_A5	62..260	CDD:349839	93/200 (47%)
		Cys-loop	177..191	CDD:349839	8/13 (62%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	203	1.000	Domainoid score	I2891
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1057372at2759
OrthoFinder	1	1.000	-	-		FOG0000415
OrthoInspector	1	1.000	-	-		otm49077
Panther	1	1.100	-	-	O	PTHR18945
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X127
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	7.020