Protein Alignment CG8916 and gabrg3

DIOPT Version :10

• Sequence 1: NP_573090.3
• Gene: CG8916 / 32553
• FlyBaseID: FBgn0030707
• Length: 612
• Species: Drosophila melanogaster
• Sequence 2: XP_002931686.2
• Gene: gabrg3 / 100494037
• XenbaseID: XB-GENE-6041774
• Length: 446
• Species: Xenopus tropicalis
• Alignment Length: 512
• Identity: 169/512 - (33%)
• Similarity: 253/512 - (49%)
• Gaps: 105/512 - (20%)

  Fly    91 NQRRVRRKAAADMLSRNISMILENLLKRYEQSQLPTHGQGVPTVVQTNILIRSMGPVSELDMDYS 155
            ||:.|......|   .:.::||..|||.|::...|..|. .|||:..:|.:.|:||||.::|:|.
 Frog    33 NQKWVLAPKTQD---TDATLILNKLLKEYDKKLRPDIGI-KPTVIDVDIYVNSIGPVSSINMEYQ 93

  Fly   156 MDCYFRQYWRDKRLSFKGPIKSLSLSIKMLDKIWRPDTYFYNGKHSQIHMITVPNKLLRLDQNGG 220
            :|.:|.|.|.|.||.|...:|.|:|:..|:..||.|||.|.|.|.::.|.||.||:|||:..:|.
 Frog    94 IDIFFAQTWTDSRLRFNSTMKILTLNSNMVGLIWIPDTIFRNSKTAEAHWITTPNQLLRIWNDGK 158

  Fly   221 ILYSMRLTIKATCPMELQNFPMDRQSCPLVIGSYGYINQQLIYEWKNQDDAVSFVPGMTLNQFDL 285
            |||::||||.|.|.::|.|||||..||||:..||||..::::|.|:......:......|.|||.
 Frog   159 ILYTLRLTINAECQLQLHNFPMDEHSCPLIFSSYGYPREEMVYRWRKNSVETANQKSWRLYQFDF 223

  Fly   286 ISMMHRNFTTVRR--EGDFSVLHVAFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREATSDRV 348
            :.:  ||.|.:.:  .||:.|:.|.|:|.|..|||.||.|:||||.||||||||||.::||..|.
 Frog   224 MGL--RNTTEIVKTSAGDYIVMTVYFDLSRRMGYFTIQTYIPCILTVVLSWVSFWIKKDATPART 286

  Fly   349 SLCVTSVLTLSTISLDSRTDLPKVKYATALDWFLLMSFLYCIATLLEFAGVHYFTKLGSGESPQL 413
            :|.:|:|||::|:|..:|..||:|.|.||:|.|:.:.||:..|.|:|:|.::|::   |.:.|:
 Frog   287 ALGITTVLTMTTLSTIARKSLPRVSYVTAMDLFVTVCFLFVFAALIEYAALNYYS---SCKKPR- 347

  Fly   414 EDQWEDICIANSLSDHAGEVDGDGEADADPFADEDSSNGS--ENDDNEAGASESVESKSGVCVCN 476
                   |.....|:::       ..|..|.....:.|.|  ..:..||...|.::.|.    |
 Frog   348 -------CTKKKKSNYS-------VLDMRPPPTVITLNNSLYWQEFEEACVYECLDGKD----C- 393

  Fly   477 KNDALGLEYEVSLQNSLAGAGFLKRNAIFCPTYNDPSYILPNTMERTTQTEPPAVSRLHQMWMCL 541
                                     .:.|| .|::                            |
 Frog   394 -------------------------QSFFC-CYDE----------------------------C- 403

  Fly   542 KSDNSFRKQRERNAAAQKSEQGGANCYVNSVSLIDRVARIAFPMSFAFLNLLYWWAY 598
             ...|:|:.|               .:::.:.| |..:|:.||.||...||:||..|
 Frog   404 -KSGSWRRGR---------------IHIDLLEL-DSYSRVFFPTSFLLFNLVYWVGY 443

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8916	NP_573090.3	LIC	92..598	CDD:455710	167/509 (33%)
		LGIC_ECD_GABAR_GRD-like	132..314	CDD:349808	78/183 (43%)
		Cys-loop	233..247	CDD:349808	7/13 (54%)
gabrg3	XP_002931686.2	LIC	50..443	CDD:455710	164/490 (33%)
		LGIC_ECD_GABAAR_G	71..252	CDD:349801	77/182 (42%)
		Cys-loop	171..185	CDD:349801	7/13 (54%)