Protein Alignment CG8916 and gabra1

DIOPT Version :10

• Sequence 1: NP_573090.3
• Gene: CG8916 / 32553
• FlyBaseID: FBgn0030707
• Length: 612
• Species: Drosophila melanogaster
• Sequence 2: XP_031754594.1
• Gene: gabra1 / 100490334
• XenbaseID: XB-GENE-6033338
• Length: 454
• Species: Xenopus tropicalis
• Alignment Length: 522
• Identity: 185/522 - (35%)
• Similarity: 265/522 - (50%)
• Gaps: 111/522 - (21%)

  Fly    86 SSEISNQRRVRRKAAADMLSRNISM---ILENLLKRYEQSQLPTHGQGVPTVVQTNILIRSMGPV 147
            :||||     ..::..|.:..|.::   ||:.||..|:....|..|:.| |.|.|:|.:.|.|||
 Frog    21 TSEIS-----CGQSTQDEIKDNTTIFTRILDRLLDGYDNRLRPGLGERV-TEVNTDIFVTSFGPV 79

  Fly   148 SELDMDYSMDCYFRQYWRDKRLSFKGPIKSLSLSIKMLDKIWRPDTYFYNGKHSQIHMITVPNKL 212
            |:.||:|::|.:|||.|||:||.||||:..|.|:..|..|||.|||:|:|||.|..|.:|:||||
 Frog    80 SDHDMEYTIDVFFRQGWRDERLKFKGPMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKL 144

  Fly   213 LRLDQNGGILYSMRLTIKATCPMELQNFPMDRQSCPLVIGSYGYINQQLIYEWKNQDDAVSFV-- 275
            ||:.::|.:||:||||::|.|||.|::||||..:|||..|||.|...:::|.| .::.::|.|
 Frog   145 LRITEDGTLLYTMRLTVRAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYSW-TREPSLSVVVA 208

  Fly   276 -PGMTLNQFDLISMMHRNFTTVRREGDFSVLHVAFNLKRHTGYFLIQVYVPCILIVVLSWVSFWI 339
             .|..|||:||:.....:.......|::.|:...|:|||..|||:||.|:|||:.|:||.||||:
 Frog   209 EDGSRLNQYDLLGQTVASGIVQSSTGEYIVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWL 273

  Fly   340 HREATSDRVSLCVTSVLTLSTISLDSRTDLPKVKYATALDWFLLMSFLYCIATLLEFAGVHYFTK 404
            :||:...|....||:|||::|:|:.:|..||||.||||:|||:.:.:.:..:.|:|||.|:||||
 Frog   274 NRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTK 338

  Fly   405 LGSGESPQLEDQWEDICIANSLSDHAGEVDGDGEADADPFADEDSSNGSENDDNEAGASESVESK 469
            .|..        |                ||.......|...:|.
 Frog   339 RGYA--------W----------------DGKSVVPEKPKKVKDP-------------------- 359

  Fly   470 SGVCVCNKNDALGLEYEVSLQNSLAGAGFLKRNAIFCPTYNDPSYILPNTMERTTQTEPPAVSRL 534
                                        .:|:|               ||....|...||.:.|.
 Frog   360 ----------------------------LIKKN---------------NTYASATANYPPTIPRD 381

  Fly   535 HQMWMCLKSDNSFRKQRE---RNAAAQKSEQGGANCYVNSVSLIDRVARIAFPMSFAFLNLLYWW 596
            ..:....||.....|..|   :.|..:|:        .||||.|||::|||||:.|...||:||.
 Frog   382 PGLATIAKSATIEPKDIEPKPKPAEPKKT--------FNSVSKIDRLSRIAFPLLFGTFNLVYWA 438

  Fly   597 AY 598
            .|
 Frog   439 TY 440

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8916	NP_573090.3	LIC	92..598	CDD:455710	180/514 (35%)
		LGIC_ECD_GABAR_GRD-like	132..314	CDD:349808	85/184 (46%)
		Cys-loop	233..247	CDD:349808	8/13 (62%)
gabra1	XP_031754594.1	LIC	11..440	CDD:455710	184/520 (35%)
		LGIC_ECD_GABAAR_A1	55..248	CDD:349835	88/194 (45%)
		Cys-loop	165..179	CDD:349835	8/13 (62%)