Protein Alignment CG8916 and gabra1

DIOPT Version :9

• Sequence 1: NP_573090.3
• Gene: CG8916 / 32553
• FlyBaseID: FBgn0030707
• Length: 612
• Species: Drosophila melanogaster
• Sequence 2: XP_031754594.1
• Gene: gabra1 / 100490334
• XenbaseID: XB-GENE-6033338
• Length: 454
• Species: Xenopus tropicalis
• Alignment Length: 522
• Identity: 185/522 - (35%)
• Similarity: 265/522 - (50%)
• Gaps: 111/522 - (21%)

  Fly    86 SSEISNQRRVRRKAAADMLSRNISM---ILENLLKRYEQSQLPTHGQGVPTVVQTNILIRSMGPV 147
            :||||     ..::..|.:..|.::   ||:.||..|:....|..|:.| |.|.|:|.:.|.|||
 Frog    21 TSEIS-----CGQSTQDEIKDNTTIFTRILDRLLDGYDNRLRPGLGERV-TEVNTDIFVTSFGPV 79

  Fly   148 SELDMDYSMDCYFRQYWRDKRLSFKGPIKSLSLSIKMLDKIWRPDTYFYNGKHSQIHMITVPNKL 212
            |:.||:|::|.:|||.|||:||.||||:..|.|:..|..|||.|||:|:|||.|..|.:|:||||
 Frog    80 SDHDMEYTIDVFFRQGWRDERLKFKGPMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKL 144

  Fly   213 LRLDQNGGILYSMRLTIKATCPMELQNFPMDRQSCPLVIGSYGYINQQLIYEWKNQDDAVSFV-- 275
            ||:.::|.:||:||||::|.|||.|::||||..:|||..|||.|...:::|.| .::.::|.|
 Frog   145 LRITEDGTLLYTMRLTVRAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYSW-TREPSLSVVVA 208

  Fly   276 -PGMTLNQFDLISMMHRNFTTVRREGDFSVLHVAFNLKRHTGYFLIQVYVPCILIVVLSWVSFWI 339
             .|..|||:||:.....:.......|::.|:...|:|||..|||:||.|:|||:.|:||.||||:
 Frog   209 EDGSRLNQYDLLGQTVASGIVQSSTGEYIVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWL 273

  Fly   340 HREATSDRVSLCVTSVLTLSTISLDSRTDLPKVKYATALDWFLLMSFLYCIATLLEFAGVHYFTK 404
            :||:...|....||:|||::|:|:.:|..||||.||||:|||:.:.:.:..:.|:|||.|:||||
 Frog   274 NRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTK 338

  Fly   405 LGSGESPQLEDQWEDICIANSLSDHAGEVDGDGEADADPFADEDSSNGSENDDNEAGASESVESK 469
            .|..        |                ||.......|...:|.
 Frog   339 RGYA--------W----------------DGKSVVPEKPKKVKDP-------------------- 359

  Fly   470 SGVCVCNKNDALGLEYEVSLQNSLAGAGFLKRNAIFCPTYNDPSYILPNTMERTTQTEPPAVSRL 534
                                        .:|:|               ||....|...||.:.|.
 Frog   360 ----------------------------LIKKN---------------NTYASATANYPPTIPRD 381

  Fly   535 HQMWMCLKSDNSFRKQRE---RNAAAQKSEQGGANCYVNSVSLIDRVARIAFPMSFAFLNLLYWW 596
            ..:....||.....|..|   :.|..:|:        .||||.|||::|||||:.|...||:||.
 Frog   382 PGLATIAKSATIEPKDIEPKPKPAEPKKT--------FNSVSKIDRLSRIAFPLLFGTFNLVYWA 438

  Fly   597 AY 598
            .|
 Frog   439 TY 440

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8916	NP_573090.3	LIC	92..598	CDD:273305	180/514 (35%)
		Neur_chan_LBD	111..315	CDD:280998	94/206 (46%)
		Neur_chan_memb	322..>403	CDD:280999	39/80 (49%)
gabra1	XP_031754594.1	LGIC_ECD_GABAAR_A1	55..248	CDD:349835	88/194 (45%)
		LIC	11..440	CDD:273305	184/520 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	203	1.000	Domainoid score	I2891
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1057372at2759
OrthoFinder	1	1.000	-	-		FOG0000415
OrthoInspector	1	1.000	-	-		otm49077
Panther	1	1.100	-	-	O	PTHR18945
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X127
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	7.020