Protein Alignment CG8916 and gabrd

DIOPT Version :10

• Sequence 1: NP_573090.3
• Gene: CG8916 / 32553
• FlyBaseID: FBgn0030707
• Length: 612
• Species: Drosophila melanogaster
• Sequence 2: XP_017951272.2
• Gene: gabrd / 100488161
• XenbaseID: XB-GENE-988598
• Length: 450
• Species: Xenopus tropicalis
• Alignment Length: 510
• Identity: 146/510 - (28%)
• Similarity: 238/510 - (46%)
• Gaps: 102/510 - (20%)

  Fly   102 DMLSRNISMI----LENLLKRYEQSQLPTHGQGVPTVVQTNILIRSMGPVSELDMDYSMDCYFRQ 162
            :.:..||.:.    |::|:|.|.::..|..| |.|.:|..::.:.|:..:||::|:|:|..:..|
 Frog    28 EFIGSNIEISWVPNLDDLMKGYARNFRPGIG-GAPVIVAVDVEVTSIDHISEVNMEYTMTVFLHQ 91

  Fly   163 YWRDKRLSFKGPIKSLSLSIKMLDKIWRPDTYFYNGKHSQIHMITVPNKLLRLDQNGGILYSMRL 227
            .|||:|||:....|:|.|..:.::|:|.|||:..|.|.:..|.:||.|||:||..:|.||||.|:
 Frog    92 SWRDERLSYNHTNKTLGLDSRFVEKLWLPDTFIVNAKSAWFHDVTVENKLIRLQPDGVILYSSRI 156

  Fly   228 TIKATCPMELQNFPMDRQSCPLVIGSYGYINQQLIYEWKNQDDAVSFVPGMTLNQFDLIS-MMHR 291
            |...:|.|:|..:|||.|.|.|.:.||||.::.::|.|....:....:..:.|.||.:.: ...:
 Frog   157 TSTVSCDMDLTKYPMDEQECMLELESYGYSSEDILYRWSENQEKNHGLDKIELAQFTVTNYRFTK 221

  Fly   292 NFTTVRREGDFSVLHVAFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREATSDRVSLCVTSVL 356
            |...::..|:|..|.:.|:|:|:.|.::|:.|||.||:|.:|||||||.:.|...||||.:|:||
 Frog   222 NEMILKSAGEFPRLSLHFHLRRNRGVYIIESYVPSILLVAMSWVSFWISQAAVPARVSLGITTVL 286

  Fly   357 TLSTISLDSRTDLPKVKYATALDWFLLMSFLYCIATLLEFAGVHYFTKLGSGESPQLEDQWEDIC 421
            |::|:.:.:||.||:.....|||.:.|:.:::..|.|:|:|..||
 Frog   287 TMTTLMVSARTSLPRASAVKALDVYFLICYVFVFAALVEYAFAHY-------------------- 331

  Fly   422 IANSLSDHAGEVDGDGEADADPFADEDSSNGSENDDNEAGASESVESKSGVCVCNKNDALGLEYE 486
                              .||....|.....:...:.:...:|.    ....|......||::..
 Frog   332 ------------------SADYIKKEKVKTKASKKNKQVQMNEG----QYAIVLLSLSILGMDQS 374

  Fly   487 VSL--------QNSLAGAGFLKRNAIFCPTYNDPSYILPNTMERTTQTEPPAVSRLHQMWMCLKS 543
            ::|        ||.....|..|.....|   .||              :|...|||..:...:::
 Frog   375 LTLINKHHFATQNEARLEGMRKDKLQIC---RDP--------------KPEKESRLKSLLRPIEA 422

  Fly   544 DNSFRKQRERNAAAQKSEQGGANCYVNSVSLIDRVARIAFPMSFAFLNLLYWWAY 598
            |:                             ||..||..||.:||.:|::||.||
 Frog   423 DS-----------------------------IDVYARAVFPAAFAAVNIIYWVAY 448

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8916	NP_573090.3	LIC	92..598	CDD:455710	144/508 (28%)
		LGIC_ECD_GABAR_GRD-like	132..314	CDD:349808	64/182 (35%)
		Cys-loop	233..247	CDD:349808	7/13 (54%)
gabrd	XP_017951272.2	LIC	42..448	CDD:455710	142/494 (29%)
		LGIC_ECD	61..244	CDD:475126	64/182 (35%)