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Protein Alignment Lrp4 and LRP10

DIOPT Version :10

Sequence 1:	NP_727914.1	Gene:	Lrp4 / 32552	FlyBaseID:	FBgn0030706	Length:	2009	Species:	Drosophila melanogaster
Sequence 2:	XP_005267567.1	Gene:	LRP10 / 26020	HGNCID:	14553	Length:	721	Species:	Homo sapiens

Alignment Length:	335	Identity:	86/335 - (25%)
Similarity:	118/335 - (35%)	Gaps:	118/335 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly   255 YSDETHCGARTN---CTDDQFECLNGFCIPRTWVCDGENDCKDFSDETHCNR------------- 303
            ||.....||..:   |..::|:|||..|:.....|||.:.|.|.|||..|:.
Human   133 YSQAPLHGASADWLMCLQEEFQCLNHRCVSAVQRCDGVDACGDGSDEAGCSSDPFPGLTPRPVPS 197

  Fly   304 --TTCTDEHF-------------------TC------NDGYCISLAFRC------------DG-- 327
              ...|.|.|                   :|      :||..:::.|..            ||
Human   198 LPCNVTLEDFYGVFSSPGYTHLASVSHPQSCHWLLDPHDGRRLAVRFTALDLGFGDAVHVYDGPG 262

  Fly   328 -----------EHDCNDNS---DELKCAAVIN------SCPEG---EFKCRG------------- 356
                       .|..|..:   :.|...||::      |...|   .:..||
Human   263 PPESSRLLRSLTHFSNGKAVTVETLSGQAVVSYHTVAWSNGRGFNATYHVRGYCLPWDRPCGLGS 327

  Fly   357 GLGGAGGPSGQCILNRFRCDGDNDCGDWSDEENCPQKPSLCTSNEYKC-ADGT-----CIPKRWK 415
            |||...|...:|.....||||..||.|.:|||:||.    |....:.| |.||     |.....:
Human   328 GLGAGEGLGERCYSEAQRCDGSWDCADGTDEEDCPG----CPPGHFPCGAAGTSGATACYLPADR 388

  Fly   416 CDKEQDCDGGEDENDCGSLGSEHPLTCGSDEFTCNNGRCILKTWLCDGYPDCAAGEDEVECHLQC 480
            |:.:..|..|.||..|     .|   |....|.|.:.:|:.:||:|||.||||.|.||.:|
Human   389 CNYQTFCADGADERRC-----RH---CQPGNFRCRDEKCVYETWVCDGQPDCADGSDEWDC---- 441

  Fly   481 DLGQFLCPTK 490
               .::.|.|
Human   442 ---SYVLPRK 448

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 592.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.