Protein Alignment CycD and CCNG1

DIOPT Version :10

• Sequence 1: NP_523355.2
• Gene: CycD / 32551
• FlyBaseID: FBgn0010315
• Length: 477
• Species: Drosophila melanogaster
• Sequence 2: XP_047273818.1
• Gene: CCNG1 / 900
• HGNCID: 1592
• Length: 302
• Species: Homo sapiens
• Alignment Length: 242
• Identity: 61/242 - (25%)
• Similarity: 96/242 - (39%)
• Gaps: 45/242 - (18%)

  Fly   124 ERLTTTADPPATDNVNTAIGDPTLYSDRCLENF--LKVEEKHHKIPDTYFSIQKD----ITPPMR 182
            |.||||........:|..:..    ..||....  |::.|..|           |    :|..:|
Human     3 EVLTTTDSQKLLHQLNALLEQ----ESRCQPKVCGLRLIESAH-----------DNGLRMTARLR 52

  Fly   183 KIVAEWMMEVCAEENCQEEVVLLALNYMDRFLSSKSVRKTQLQILAAACLLLASK-LREPSCRAL 246
            ....:.::.:........|...||:|.:|||||...|:...|..:..:|..||.| :.|.....|
Human    53 DFEVKDLLSLTQFFGFDTETFSLAVNLLDRFLSKMKVQPKHLGCVGLSCFYLAVKSIEEERNVPL 117

  Fly   247 SVDLLVVYTDNSIYK---DDLIKWELYVLSRLGWDLSSVTPLDFLE----LLMMRLPIGSKNFPD 304
            :.||:.:    |.|:   .||::.|..||.::.|.:.:.|...||:    ||...||:..:|  .
Human   118 ATDLIRI----SQYRFTVSDLMRMEKIVLEKVCWKVKATTAFQFLQLYYSLLQENLPLERRN--S 176

  Fly   305 INIGKVRGHAQAFISLAAKEH---KFAKFSASTIAASSIAASMNGLK 348
            ||..::....:|.       |   .|:|...|.:|.|.||..:...|
Human   177 INFERLEAQLKAC-------HCRIIFSKAKPSVLALSIIALEIQAQK 216

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CycD	NP_523355.2	CYCLIN_SF	144..278	CDD:477360	34/143 (24%)
		CYCLIN_CCND_rpt2	283..387	CDD:410220	20/73 (27%)
CCNG1	XP_047273818.1	CYCLIN_CCNG1	51..148	CDD:410286	27/100 (27%)