Protein Alignment CycD and CLN2

DIOPT Version :10

• Sequence 1: NP_523355.2
• Gene: CycD / 32551
• FlyBaseID: FBgn0010315
• Length: 477
• Species: Drosophila melanogaster
• Sequence 2: NP_015067.1
• Gene: CLN2 / 855819
• SGDID: S000006177
• Length: 545
• Species: Saccharomyces cerevisiae
• Alignment Length: 402
• Identity: 66/402 - (16%)
• Similarity: 144/402 - (35%)
• Gaps: 99/402 - (24%)

  Fly   153 LENFLKVEEKHHKIPDTYFS-------------IQKDITP-PMRKIVAEWMMEVCAEENCQEEVV 203
            |.:|..::|.|.:|.....:             .|.::.| ..|..:..::.|:.........:.
Yeast    31 LSHFEMLQEYHQEISTNVIAQSCKFKPNPKLIDQQPEMNPVETRSNIITFLFELSVVTRVTNGIF 95

  Fly   204 LLALNYMDRFLSSKSVRKTQLQILAAACLLLASKL---------------------REPSCRALS 247
            ..::...||:.|.:.|.:.|.:::.|.||.||:|.                     ..|..|...
Yeast    96 FHSVRLYDRYCSKRIVLRDQAKLVVATCLWLAAKTWGGCNHIINNVVIPTGGRFYGPNPRARIPR 160

  Fly   248 VDLLVVYT-DNSIYKDDL-IKWELYVLSRLGWDLSSVTPLDFL----ELLMMRLPIGSKNFP-DI 305
            :..||.|. |..::.:.: ::.|.::|..|.|::......|::    |..:|:..:...... |.
Yeast   161 LSELVHYCGDGQVFDESMFLQMERHILDTLNWNIYEPMINDYVLNVDENCLMQYELYENQVTYDK 225

  Fly   306 NIGKVRGHAQAFISLAA-------------KEHKFAKFSASTIAASSIAASMNGLKWHL------ 351
            ...:.|   |:.:|..:             :|.:..|.....|........::..::.|
Yeast   226 QCSEKR---QSQLSQDSDATVDERPYQNEEEEEEDLKLKIKLINLKKFLIDVSAWQYDLLRYELF 287

  Fly   352 RSGHNLHFLLS----------LMTDLTS-VEQAQVRDCMLH--------MEDIFKEHSRNLEPFL 397
            ...|.:..:::          |||.:|| .:..::...:::        :.:::|..:..| ||:
Yeast   288 EVSHGIFSIINQFTNQDHGPFLMTPMTSESKNGEILSTLMNGIVSIPNSLMEVYKTVNGVL-PFI 351

  Fly   398 VNIDPKEMSTLYYKRRFQIHQSQHLSQISIRPLP-----------LPKAPAECVEQHQQQHNFGS 451
            ..:  ||.. |..:|:.||..:.::|:......|           :| :||...:.|....|..|
Yeast   352 NQV--KEYH-LDLQRKLQIASNLNISRKLTISTPSCSFENSNSTSIP-SPASSSQSHTPMRNMSS 412

  Fly   452 AAPHRTHTCKMQ 463
            .:.:...:..|:
Yeast   413 LSDNSVFSRNME 424

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CycD	NP_523355.2	CYCLIN_SF	144..278	CDD:477360	29/161 (18%)
		CYCLIN_CCND_rpt2	283..387	CDD:410220	17/146 (12%)
CLN2	NP_015067.1	COG5024	33..524	CDD:227357	65/400 (16%)