Protein Alignment CycD and CLN1

DIOPT Version :10

• Sequence 1: NP_523355.2
• Gene: CycD / 32551
• FlyBaseID: FBgn0010315
• Length: 477
• Species: Drosophila melanogaster
• Sequence 2: NP_013926.1
• Gene: CLN1 / 855239
• SGDID: S000004812
• Length: 546
• Species: Saccharomyces cerevisiae
• Alignment Length: 315
• Identity: 52/315 - (16%)
• Similarity: 112/315 - (35%)
• Gaps: 91/315 - (28%)

  Fly   153 LENFLKVEEKHHKIPDTYFSIQKDITPP---------------MRKIVAEWMMEVCAEENCQEEV 202
            |.::..::|.|.:|..... :|...|.|               .|:.:..::.::.........:
Yeast    29 LTHYETIQEYHEEISQNVL-VQSSKTKPDIKLIDQQPEMNPHQTREAIVTFLYQLSVMTRVSNGI 92

  Fly   203 VLLALNYMDRFLSSKSVRKTQLQILAAACLLLASKL---------------------REPSCRAL 246
            ...|:.:.||:.|.:.|.|.|.:::...||.||:|.                     ..|..|..
Yeast    93 FFHAVRFYDRYCSKRVVLKDQAKLVVGTCLWLAAKTWGGCNHIINNVSIPTGGRFYGPNPRARIP 157

  Fly   247 SVDLLVVYTDNSIYKDD--LIKWELYVLSRLGWDLSSVTPLDFL-----------ELLMMRLPIG 298
            .:..||.|...|...|:  .|:.|.::|..|.||:......|::           ||...:|...
Yeast   158 RLSELVHYCGGSDLFDESMFIQMERHILDTLNWDVYEPMINDYILNVDENCLIQYELYKNQLQNN 222

  Fly   299 SKNFPDINIGKVRGHAQAFISLAAKEHKFAKFSASTIAASSIAASMNGLKWHLRSGHNLHFLLSL 363
            :.|..:.:. |.:..:........:||         |::|..:..::|
Yeast   223 NSNGKEWSC-KRKSQSSDDSDATVEEH---------ISSSPQSTGLDG----------------- 260

  Fly   364 MTDLTSVEQAQVRDCMLHMEDIFKEHSRNLEPFLVNIDPKEMSTLYYKRRFQIHQ 418
              |.|::::.:..:..:.:        .||:.||:::...:.:.|    :|::::
Yeast   261 --DTTTMDEDEELNSKIKL--------INLKRFLIDLSCWQYNLL----KFELYE 301

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CycD	NP_523355.2	CYCLIN_SF	144..278	CDD:477360	31/162 (19%)
		CYCLIN_CCND_rpt2	283..387	CDD:410220	13/114 (11%)
CLN1	NP_013926.1	COG5024	31..539	CDD:227357	51/313 (16%)