DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CycD and CYCD4;1

DIOPT Version :9

Sequence 1:	NP_523355.2	Gene:	CycD / 32551	FlyBaseID:	FBgn0010315	Length:	477	Species:	Drosophila melanogaster
Sequence 2:	NP_001190620.1	Gene:	CYCD4;1 / 836667	AraportID:	AT5G65420	Length:	318	Species:	Arabidopsis thaliana

Alignment Length:	237	Identity:	64/237 - (27%)
Similarity:	106/237 - (44%)	Gaps:	40/237 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   160 EEKHHKIPDTYF----SIQKDITPPMRKIVAEWMMEV---CA--EENCQEE-----VVLLALNYM 210
            :||.|...|.|.    |...|:... |:....|:.::   |.  .|.|:..     ...||:||:
plant    53 KEKQHLPSDDYIKRLRSGDLDLNVG-RRDALNWIWKIRGLCRTDREACEVHQFGPLCFCLAMNYL 116

  Fly   211 DRFLSSKSVRKTQ---LQILAAACLLLASKLREPSCRALSVDLLV-----VYTDNSIYKDDLIKW 267
            |||||...:...:   ||:||.|||.||:|:.|.....| :||.|     |:...|:.     :.
plant   117 DRFLSVHDLPSGKGWILQLLAVACLSLAAKIEETEVPML-IDLQVGDPQFVFEAKSVQ-----RM 175

  Fly   268 ELYVLSRLGWDLSSVTPLDFLELLMMRLPIGSKNFPDINIGKVRGHAQAFISLAAKEHKFAKFSA 332
            ||.||::|.|.|.::||..::...:.::....:...:..|.:    :...|:...|...|.:|..
plant   176 ELLVLNKLKWRLRAITPCSYIRYFLRKMSKCDQEPSNTLISR----SLQVIASTTKGIDFLEFRP 236

  Fly   333 STIAASSIAASMNGLKWHLRSGHNLHFLLSLMTDLTSVEQAQ 374
            |.:|| ::|.|::|      ....:||..|..:.|.|:.|.:
plant   237 SEVAA-AVALSVSG------ELQRVHFDNSSFSPLFSLLQKE 271

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CycD	NP_523355.2	Cyclin_N	155..280	CDD:278560	44/141 (31%)
CycD	NP_523355.2	Cyclin_C	282..>392	CDD:281044	19/93 (20%)
CYCD4;1	NP_001190620.1	Cyclin_N	45..188	CDD:278560	44/141 (31%)
CYCD4;1	NP_001190620.1	Cyclin_C	191..>282	CDD:281044	19/92 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0656
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10177
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910