Protein Alignment CycD and CycE

DIOPT Version :10

• Sequence 1: NP_523355.2
• Gene: CycD / 32551
• FlyBaseID: FBgn0010315
• Length: 477
• Species: Drosophila melanogaster
• Sequence 2: NP_001246037.1
• Gene: CycE / 34924
• FlyBaseID: FBgn0010382
• Length: 712
• Species: Drosophila melanogaster
• Alignment Length: 500
• Identity: 106/500 - (21%)
• Similarity: 185/500 - (37%)
• Gaps: 151/500 - (30%)

  Fly    22 KRQQQMSSPAIIRDQ----SSICSSLGDAESDSHPDAQNNAVVCNMKELVYIYAS-VDSAAKNPE 81
            ||||::  ||:...:    ||:.||:..:...| .|.|:.      :||:.|.:| .:..::.|.
  Fly   134 KRQQRL--PALYGSEQGNLSSVASSVYTSPVVS-VDGQST------QELLSIRSSPAEDLSEAPH 189

  Fly    82 QLEPPPPPPPPPPPPPTATQSIQSYPRYISQEPPTSH--CQRL--DERLTTTA-----DPPATDN 137
              .|.|..|..||.|...::......||.:::..||.  .|:.  |:.|..:.     |....|:
  Fly   190 --SPLPDSPDSPPSPDRGSKQTPVVVRYAAEQVVTSTVVTQKTEDDDLLDDSCEDYSYDEDDEDD 252

  Fly   138 VNTAIGDPTLYSDR-------CLE----------NFLKVEEK-HHKIPDTYFSIQKDITPP---- 180
            |.....|..:||..       |.:          ...|.:|: ||.:.|...:::..::|.
  Fly   253 VEEEDDDVEIYSSTISPASSGCSQQQAVNGERTPGLPKHQEQIHHPVSDLMINMRTPMSPAVENG 317

  Fly   181 ----------------------------------------------MRKIVAEWMMEVCAEENCQ 199
                                                          ||.|:.:|::|||......
  Fly   318 LRQCPLPALAWANAADVWRLMCHRDEQDSRLRSISMLEQHPGLQPRMRAILLDWLIEVCEVYKLH 382

  Fly   200 EEVVLLALNYMDRFLS-SKSVRKTQLQILAAACLLLASKLRE--PSCRALSVDLLVVYTDNSIYK 261
            .|...||::|:||:|. :..|:||.||::...||.:|:|:.|  |.    .:......||.:..:
  Fly   383 RETFYLAVDYLDRYLHVAHKVQKTHLQLIGITCLFVAAKVEEIYPP----KIGEFAYVTDGACTE 443

  Fly   262 DDLIKWELYVLSRLGWDLSSVTPLDFLELLMMRLPIGSK---NFPDINIGKVRGHAQAFI----- 318
            .|::..|..:|..|.||:|.:|...:|. :.|:|.:.::   :|..|...|......|||
  Fly   444 RDILNHEKILLQALDWDISPITITGWLG-VYMQLNVNNRTPASFSQIGRQKSAEADDAFIYPQFS 507

  Fly   319 -----------SLAAKEHKFAKFSASTIAASSI--------AASMNGLKWHLRSGHNLHFLLSLM 364
                       .|...:...|.:|.|.:||::|        |...:||.|.:
  Fly   508 GFEFVQTSQLLDLCTLDVGMANYSYSVLAAAAISHTFSREMALRCSGLDWQV------------- 559

  Fly   365 TDLTSVEQAQVRDCMLHMEDIFKEHSRNLEPFLVNIDPKEMSTLY 409
                      ::.|...||..|:..|:......:|...:::|..:
  Fly   560 ----------IQPCARWMEPFFRVISQKAPYLQLNEQNEQVSNKF 594

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CycD	NP_523355.2	CYCLIN_SF	144..278	CDD:477360	41/204 (20%)
		CYCLIN_CCND_rpt2	283..387	CDD:410220	24/130 (18%)
CycE	NP_001246037.1	CYCLIN_CCNE_rpt1	327..459	CDD:410223	31/135 (23%)
		CYCLIN_CCNE_rpt2	463..576	CDD:410224	25/136 (18%)