DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CycD and ccnf

DIOPT Version :9

Sequence 1:NP_523355.2 Gene:CycD / 32551 FlyBaseID:FBgn0010315 Length:477 Species:Drosophila melanogaster
Sequence 2:NP_996931.1 Gene:ccnf / 266981 ZFINID:ZDB-GENE-021030-2 Length:764 Species:Danio rerio


Alignment Length:334 Identity:78/334 - (23%)
Similarity:139/334 - (41%) Gaps:91/334 - (27%)


- Green bases have known domain annotations that are detailed below.


  Fly   175 KDITPPMRKIVAEWMMEVCAEENCQEEVVLLALNYMDRFLSSKSVRKTQLQILAAACLLLASKLR 239
            :||| ..|.|:.:|::||...::...:|:.:.::.:||:|..:||.|.|||:|..||:::.:   
Zfish   303 QDIT-TKRYILVDWLVEVTTTKDFSSQVLHVTISCVDRYLHLRSVPKAQLQLLGIACMVICT--- 363

  Fly   240 EPSCRALSVDLLVV-----YTDNSIYKDDLIKWELYVLSRLGWDLSSVTPLDFLELLMMRLPIGS 299
                |.:|.::|.:     .|||:...:||:.....|:|.|...:.:.|.||:.|:|:..||:..
Zfish   364 ----RFISKEILTIREAVWLTDNTYQYEDLVHMMGEVISVLDGKIR
TPTVLDYGEVLLSLLPVER 424

  Fly   300 KNFPDINIGKVRGHAQAFI---SLAAKEHKFAKFSASTI-----AASSIAASMNGLK-----WHL 351
            :.          .|..::|   ||..        |.:|:     .||:|......|.     |.:
Zfish   425 RT----------AHLFSYICELSLLC--------SPATVPGPARLASAILLLTRALHNYVPVWPV 471

  Fly   352 RSGHNLHFLLSLMTDLTSVEQAQVRDCMLHM------EDIFKEHSRNLEPFLVNIDPKEMSTLYY 410
            :...|..|   ...||.|        |.|.:      :|:.|::             :.:|....
Zfish   472 QLEENTGF---SKQDLVS--------CALTLYIKCFGQDVPKDY-------------RHVSLTGV 512

  Fly   411 KRRFQIHQSQHLSQISI-------RPLPLPKAPAECVE------QHQQQHNFGS---AAPHRTHT 459
            |:||:....|.:|:.::       ..|.:|:...: ||      |..:.|.|.|   ::..|...
Zfish   513 KQRFEDDSYQQISKDTVMGFKELCHVLEVPEVEPQ-VEVSSTSGQITEMHTFLSSPTSSSKRRRA 576

  Fly   460 CKMQAQAQA 468
            ..|||...|
Zfish   577 DSMQAHRGA 585

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CycDNP_523355.2 Cyclin_N 155..280 CDD:278560 32/109 (29%)
Cyclin_C 282..>392 CDD:281044 27/128 (21%)
ccnfNP_996931.1 Nuclear localization signal 1. /evidence=ECO:0000250 19..27
Cyclin_N 299..405 CDD:278560 32/109 (29%)
Cyclin_C 428..526 CDD:281044 25/129 (19%)
Nuclear localization signal 2. /evidence=ECO:0000250 570..575 1/4 (25%)
PEST 583..738 1/3 (33%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 662..754
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C170579819
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
10.930

Return to query results.
Submit another query.