Protein Alignment CycD and Ccnd1

DIOPT Version :9

• Sequence 1: NP_523355.2
• Gene: CycD / 32551
• FlyBaseID: FBgn0010315
• Length: 477
• Species: Drosophila melanogaster
• Sequence 2: NP_001366177.1
• Gene: Ccnd1 / 12443
• MGIID: 88313
• Length: 317
• Species: Mus musculus
• Alignment Length: 293
• Identity: 107/293 - (36%)
• Similarity: 162/293 - (55%)
• Gaps: 37/293 - (12%)

  Fly   136 DNVNTAIGDPTLYSDRCLENFLKVEEKHHKIPDTYFSIQKDITPPMRKIVAEWMMEVCAEENCQE 200
            :.:..|..|..|.:||.|...||.||........:..:||:|.|.||||||.||:|||.|:.|:|
Mouse    11 ETIRRAYPDTNLLNDRVLRAMLKTEETCAPSVSYFKCVQKEIVPSMRKIVATWMLEVCEEQKCEE 75

  Fly   201 EVVLLALNYMDRFLSSKSVRKTQLQILAAACLLLASKLREPSCRALSVDLLVVYTDNSIYKDDLI 265
            ||..||:||:|||||.:.::|::||:|.|.|:.:|||::|..  .|:.:.|.:||||||..::|:
Mouse    76 EVFPLAMNYLDRFLSLEPLKKSRLQLLGATCMFVASKMKETI--PLTAEKLCIYTDNSIRPEELL 138

  Fly   266 KWELYVLSRLGWDLSSVTPLDFLELLMMRLPIGSKNFPDINIGKVRGHAQAFISLAAKEHKFAKF 330
            :.||.::::|.|:|:::||.||:|..:.::|..     |.|...:|.|||.|::|.|.:.||...
Mouse   139 QMELLLVNKLKWNLAAMTPHDFIEHFLSKMPEA-----DENKQTIRKHAQTFVALCATDVKFISN 198

  Fly   331 SASTIAASSIAASMNGLKWHLRSGHNL-------HFL---------------LSLMTD---LTSV 370
            ..|.:||.|:.|:|.||  :|.|.:|.       |||               |.|..|   |...
Mouse   199 PPSMVAAGSVVAAMQGL--NLGSPNNFLSCYRTTHFLSRVIKCDPVKALATGLWLNKDPLHLRPP 261

  Fly   371 EQAQVRDCMLHMEDIFKEHSRNLEPFLVNIDPK 403
            .|..:|.|...:|.:.:...|..:.   |:|||
Mouse   262 LQDCLRACQEQIEALLESSLRQAQQ---NVDPK 291

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CycD	NP_523355.2	Cyclin_N	155..280	CDD:278560	56/124 (45%)
		Cyclin_C	282..>392	CDD:281044	39/134 (29%)
Ccnd1	NP_001366177.1	CYCLIN_CCND1_rpt1	3..151	CDD:410276	61/141 (43%)
		CYCLIN_CCND1_rpt2	156..287	CDD:410279	40/140 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167836344
Domainoid	1	1.000	125	1.000	Domainoid score	I5444
eggNOG	1	0.900	-	-		E1_KOG0656
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	174	1.000	Inparanoid score	I4065
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001275
OrthoInspector	1	1.000	-	-		otm43415
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10177
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4378
SonicParanoid	1	1.000	-	-		X1298
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	12	11.880