Protein Alignment tay and Fbrsl1

DIOPT Version :10

• Sequence 1: NP_573086.2
• Gene: tay / 32547
• FlyBaseID: FBgn0260938
• Length: 2486
• Species: Drosophila melanogaster
• Sequence 2: XP_222254.5
• Gene: Fbrsl1 / 304572
• RGDID: 1563342
• Length: 1037
• Species: Rattus norvegicus
• Alignment Length: 1269
• Identity: 284/1269 - (22%)
• Similarity: 413/1269 - (32%)
• Gaps: 422/1269 - (33%)

  Fly  1310 RSSDSRNSR-ESPAS-LKSTPS----NIGLNVS--MAPT-LRSITPLNNSSAISSGASQPVVSVV 1365
            |...:|::| :||:| .:..||    |.||:.:  ..|| ||:..|.......||...:.|:.
  Rat    20 RREAARDARAQSPSSGEEPEPSPGKENAGLHGAPPQRPTPLRAARPPRRRRRESSSQEEEVID-- 82

  Fly  1366 PSANSTALSMSNPHISHSHHVPAYASGAFSSSAAAGTSTPNSGLSTLAVTSLSTSAAPQPHSHFP 1430
                                  .:|..:||:                 :.:|....|.:||....
  Rat    83 ----------------------GFAIASFST-----------------LEALEKDMALKPHERKE 108

  Fly  1431 QSTQMLPQSGNFSSVSHLLTTHPMSSQNQPMVRCGST---LYSQSSAAATAP------------P 1480
            :..|.|.:.             |..|:|.|.......   |...|....|.|            |
  Rat   109 KWDQRLVKK-------------PRESENCPSAELSENRQPLEVGSPTCDTEPTCDEGTRKVPLQP 160

  Fly  1481 SAAAAV--------SNFTPSVLAVQSLTTAVTSSSSSPSTLSSSVIQKVISPKGESPCNKDRDSS 1537
            |....|        ::...|||...|     :..|||...||.|..| .:|.:|.| |:.:....
  Rat   161 SKQMKVTMARGGDRNSDDDSVLEASS-----SQHSSSRDQLSDSSAQ-AVSGRGYS-CDSESGMD 218

  Fly  1538 YSTNIRSHGASTMLPGASQGIGLG---SSFCGIAPSQYGGTGTPVLSSSSSMP----------PG 1589
            ...::.|.  ....|...:|.|.|   .:..|..|...|...:..||:.|.:|          ||
  Rat   219 DKASVGSE--KLFAPAPDKGSGRGEKSEAKAGAVPKVSGLERSSELSTESFLPATAPTPSGPLPG 281

  Fly  1590 LGNLSSYSSKAALWLNSPANAVVTTCAPTTPIVSSGSARPTPPLSNCTSMGIGMVNAASTARSSC 1654
                            :.|:.:|...||..|     ...|.|.|:             ...|.|.
  Rat   282 ----------------ARASPLVKREAPIVP-----HHVPQPQLT-------------PQHRGSL 312

  Fly  1655 NAISPLSIPATAG------------IHVSATNPSFQSSSYFPTPLAP----PPSSPSPATSSAAI 1703
            ....|||:.|..|            :|:.:.:.|..:.|..|..||.    .|..|.|..|::.:
  Rat   313 PTHVPLSLGAFVGPGPGPGQVASNSLHLHSLSRSSSTVSGTPLGLAKHVTLSPHGPGPHLSTSHL 377

  Fly  1704 ISSSASQFNPAVSHSMSSIVTTAGATTTTASSVTQPSVAAISNPVTNTPHPFSAESLF------- 1761
            ...|.:|.....:...::..|........|||:..|.            ||..|..|.
  Rat   378 ALRSQAQHQHHAAAMFAAPPTLPPPPALPASSLVIPG------------HPTDASLLISFNQPIM 430

  Fly  1762 --QPSKNDQAD--LLRRELDSRFL----DRSGLAVTPTPPSSTYLRTDLQHQQHAHLHQHPQ--- 1815
              ||......|  |||:||::|||    :|.|.::.|    ...||.:.....|.|.|||..
  Rat   431 YCQPHSGILIDHELLRQELNTRFLVQNAERPGASLGP----GALLRAEFHQHTHQHTHQHTHQHT 491

  Fly  1816 ------LLPPVSAPSTPL-SAVQPSSGQIFPP----PLFKDISKISSVDPQFYRTGMGLPPGGYS 1869
                  ..|....|.||| ....||....|.|    |.|:..:..:|::              .:
  Rat   492 HQHQHTFAPFAGLPPTPLMPPTAPSPFDKFSPKLDSPYFRHSNTSNSIE--------------IT 542

  Fly  1870 GYTSAGLLHSGL----GGPTPFMPPNHLTSFAPKKTGRWNAMHVRIAWEIYYHQNKQSPEKQPGF 1930
            |.:||  :|:.|    |...|:..       |.:|.|:|.|:||:|||:||:.|.|...:..|..
  Rat   543 GRSSA--VHTFLQKAPGVSDPYRT-------AVRKPGKWCAVHVQIAWQIYHQQQKMKMQLDPHK 598

  Fly  1931 PTASSNAGSINAPIPPGNMISGGGGGMASGASTPVNNVAAIPAVGGGVLVSNGPPSVLGMKTTPT 1995
            ....:.....:.  ||..       ||.||...|.:  .|.|     :..|.|       .|.||
  Rat   599 LEVGTKLDLFSR--PPAQ-------GMFSGFHYPQD--LARP-----LFSSTG-------ATHPT 640

  Fly  1996 LGMSSTPQHILHRASEMPPSAAFPGGLP-GRLAFETSPLAASF----IGAPPSH----IGT-AVS 2050
                         |:...|||.....|| |.|   |.|.:.|.    :|:..:|    :|: |::
  Rat   641 -------------ANPFGPSAHHGSFLPTGHL---TDPFSRSSTFGGLGSLSNHAFGGLGSHALT 689

  Fly  2051 PFGRYVTPFGFTGLTHFGGHLDSWRTNAMQRSVAYHPSSAAPSPNWPVKSDPGLDNARREAEERE 2115
            |......|...|.|.......|:|  |.:.|   ..||...|.| ||...|          .||.
  Rat   690 PGSSIFAPKEGTALLGLPSPHDAW--NRLHR---VPPSFPTPPP-WPKPMD----------TERL 738

  Fly  2116 RELRDREQRERDRQRREREERERKEKEEKLKR---------------EQQERERERERDRKERER 2165
            ..|.:.: ||.|: .:|..||...||...|..               ::...|..|.....|||.
  Rat   739 SALTNHD-REPDK-GQEEHERNLLEKTRLLSHGSPIAPVGHPISSLLQRDSGELSRPGVLTEREA 801

  Fly  2166 ERREIERREMERERMLQQQRINESNKQAAVQAAAAATAPVRD--------------RSPHRNVGE 2216
            |.|..|.....:|         :..|.||...:....|.:.|              ::|.|..|
  Rat   802 ETRVKENHSPSKE---------DGAKLAARPPSPYCKAALGDCLRLAGLLGRESGKQTPDRPQG- 856

  Fly  2217 LNTEIRIKEEHPRTKEEQDV--MLLRASAAAVGVG------DP---RYHSSSLAAAQASAAAAAA 2270
               ::::|||. |..|..|:  :.:.::|..:|:|      ||   .|....|
  Rat   857 ---DVKVKEER-REDETPDLTGVSVHSTATHLGLGTSGFVWDPPRDTYRGLDL------------ 905

  Fly  2271 HHHHANFMAASRHGLP-PPPSHLTRTMMPPTLSVGGPITHFGAPAPPGWGIDPYRDPYPILR--- 2331
                      .|...| |||:                    ..|||.......|||     |
  Rat   906 ----------PRRSFPAPPPA--------------------AGPAPFELSERAYRD-----RESH 935

  Fly  2332 -YNPIMEAALRHEAEERQKAINIYAA-QSAAHLRSKEPSPI--------PPSVGSLGPPPPHHRL 2386
             |:|.....:|.|..||.:|.:..|| ..|.|.....|..:        ||:..:||.|||
  Rat   936 DYSPERLREVRREELERARAPDSDAALLPAMHYPRLAPGALHGALLARTPPAAAALGAPPP---- 996

  Fly  2387 QIVSSVAQSGVQQPGPPSQQQQQQMSSGGGMVKN 2420
                .|...||  |.||::.:...::.|.|..::
  Rat   997 ----LVTAGGV--PTPPARPRTTPLALGPGEARD 1024

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tay	NP_573086.2	Auts2	1900..>2023	CDD:464656	32/122 (26%)
Fbrsl1	XP_222254.5	Auts2	568..771	CDD:464656	70/259 (27%)