Protein Alignment tay and fbrs

DIOPT Version :9

• Sequence 1: NP_001259585.1
• Gene: tay / 32547
• FlyBaseID: FBgn0260938
• Length: 2486
• Species: Drosophila melanogaster
• Sequence 2: XP_003199661.2
• Gene: fbrs / 100535921
• ZFINID: ZDB-GENE-111207-1
• Length: 1247
• Species: Danio rerio
• Alignment Length: 1310
• Identity: 272/1310 - (20%)
• Similarity: 413/1310 - (31%)
• Gaps: 527/1310 - (40%)

  Fly  1439 SGNFSSVSHLLTTHPMS----SQN-QP--MVRCGSTLYSQSSAAATA------PPSAAAAVSNFT 1490
            |||.....::..|...|    |.| :|  :|.....:.:.|::||..      |.:::..:.:.|
Zfish   168 SGNHMETGYICDTESESGDKASDNMEPAFIVFTSEAVNANSASAAAGNGCPLLPSNSSVPLLSVT 232

  Fly  1491 PSVLAV---------QSLTTAVTSSSSSPSTLSSSVIQKVISPKGESPCNKDRDSSYSTNIRSHG 1546
            |.|..:         |.....:::|||.||.                       :::||
Zfish   233 PRVSGLERSQERSMEQPYPEPISTSSSLPSL-----------------------AAHST------ 268

  Fly  1547 ASTMLPGASQGIGLGSSFCGIAPSQYGGTGTP-------------------VLSSSSSMPPGLGN 1592
                           :|...:.|.|..|.|.|                   .|.|.|..|.|..|
Zfish   269 ---------------ASVSNLLPEQRNGNGGPHHRHNASSPQHKHKNFLPFHLKSQSMYPMGNNN 318

  Fly  1593 LSSYSSKAALWLNSPANAVVTTCAPTTPIVSSGSARPTPPLSNCTSMGIGMVNAASTARSSCNAI 1657
            .||.|.|                 |.....||.|.||..|   .||:.:|      ........:
Zfish   319 RSSTSGK-----------------PPASSSSSSSIRPPTP---ATSVSLG------RGPGGVGTV 357

  Fly  1658 SPLSIPATAGIHVSATNPSFQSSSYFPTPLAPPPS-----SPSPATSSAAIISSS---ASQFNPA 1714
            .|.|.|:...:             :.|:|..|||.     ||.|:|....|::.|   ::...|:
Zfish   358 RPSSRPSPGAV-------------FTPSPNLPPPPPLMQVSPHPSTDQDLILTESNGASASGGPS 409

  Fly  1715 VSHSMSSIVTTAGATTTTASSVTQPSVAAISNPVTNTPHPFSAESLFQPSKNDQADLLRRELDSR 1779
            ||:|.|.        |::.||..|.|:
Zfish   410 VSNSNSG--------TSSRSSQAQTSI-------------------------------------- 428

  Fly  1780 FLDRSGLAVTPTPPSSTYLRTDLQHQ-QHAHLHQHPQLLPPVSAPSTPLSAVQPSSGQI---FPP 1840
                         |:..|......|| ||.|.|||  .|.|.:||...|....|  |:|   |..
Zfish   429 -------------PTMAYQFHHHNHQHQHTHTHQH--FLHPTAAPPPQLFEKYP--GKIDGLFRH 476

  Fly  1841 PLFKDISKISSVDPQFYRTGMGLPP-----GGYSG------------YTSAGLLHSGLGGPTPFM 1888
            |.|          ||:..:..|:.|     |.:|.            ..:|..:.||||...|.:
Zfish   477 PFF----------PQYPPSVPGIQPVLPSTGPFSSLHGAFQPKLVALQGAAPEMTSGLGVVPPHL 531

  Fly  1889 PPN-HLT-SFAP-----KKTGRWNAMHVRIAWEIYYHQNK-----QSPEK-------QPGFPTAS 1934
            .|. .|| ||||     .|.|:|.|||||:||.|..||.|     ..|:|       .|..|...
Zfish   532 QPKARLTDSFAPPPKVSNKPGKWCAMHVRVAWMILRHQEKVKLMHADPQKLDLRNELLPRLPGPG 596

  Fly  1935 ----SNAGSINAPIPPGNMISGGGG-----GMASGASTPV-----------------------NN 1967
                ...|.:..|:.|.:.::..||     |..:.:|||.                       .:
Zfish   597 IGGLGGLGPLGGPLGPAHDLTRPGGLFAATGGVNPSSTPFMPPSTPHSSFLTPAAHLDPYVHSPH 661

  Fly  1968 VAAIPAVGGGVLVSNGPP----SVLGMKTTPT------LGMSSTPQHILHRASEMPPSAAFPGGL 2022
            .:::.|:|.|.....|.|    ||.|.||.|:      ||....|.:.||    :|| |:||.|
Zfish   662 FSSLGALGSGAFGGLGSPTIAASVFGHKTEPSASAVGGLGNPHDPWNRLH----VPP-ASFPSG- 720

  Fly  2023 PGRLAFETSPLAASFIGAPPSHIGTAVSPFGRYVTPFGFTGLTHFGGHLDSWRTNAMQRSVAYHP 2087
                        :|:...|...     ...|:.|..   ..|||.....|       :.|:.|
Zfish   721 ------------SSWAKGPEKR-----EDRGKEVER---RELTHIKDEKD-------RDSILY-- 756

  Fly  2088 SSAAPSPNWPVKSDPGLDNARREAEERERELRDREQRERDRQRREREERERKEKEEKLKREQQER 2152
                  ...||:..||:.:.:..:......:...........:.:.:.|||            ||
Zfish   757 ------GRQPVRMSPGVPSLKHRSSTPSSHINGLGSLTGSGVQSDGQSRER------------ER 803

  Fly  2153 ERERERDRKERERER----------------------------------REIERREMERERMLQQ 2183
            |||||.|::.....|                                  .::..|:.......:.
Zfish   804 ERERESDKRHHSASRPPASASSTAPDRPRSSTSSILTTSPSNVPLATSPLDLFHRQPSHTLGTES 868

  Fly  2184 QRINESNKQAAVQAAAAATAPVRDRSPHRNV------------GELNTEIRIKEEHPRTKEEQDV 2236
            ...::........::::::.||  :.|.|..            |.|..::::|||.   |||.:.
Zfish   869 SHSSQRENNGPASSSSSSSLPV--KKPDRTTTPVSKPALGLASGLLVAQVKVKEER---KEEPEP 928

  Fly  2237 MLLRASAAAVGVGDPRYHSSSLAAAQASAAAAAAHHHHANFMAASRH-------GLPPPPSHLTR 2294
            :.:..:..||    |.::..         ..::.|.||.:..:::..       .||||..|
Zfish   929 VPISYTHPAV----PSHNFE---------RPSSRHPHHPSTPSSTLSLTPTPGVPLPPPTPH--- 977

  Fly  2295 TMMPP--TLS---------------VGGPITHFGAPAPPGWGIDP--YRDPYPILRYNPIMEAAL 2340
               ||  .||               |.|..|...||.|.|   .|  :..|.|...:....:.|:
Zfish   978 ---PPHHPLSLLDRSRAMDYGTAGLVLGAATDRFAPHPHG---PPQGHSQPTPSFPWETWRDLAI 1036

  Fly  2341 RHEAEERQKAINIYAAQSAAH--LRSKEPSPIPPSVGSLGPPPPHHRLQ---------IVSSVAQ 2394
             |:.:::|:. .:...:|..|  |||:                ||:|||         :.::||.
Zfish  1037 -HQQQQQQRR-ELLTLRSDPHLALRSE----------------PHYRLQRYFDAERAVVAAAVAN 1083

  Fly  2395 SGVQQPGPPSQQQQQQMSSGGGMVKNSGGPQAPGSIPVQ------HMISVD-------------- 2439
            |....|.|.|      .|:....|   |.|.. |.|..|      ||:..|
Zfish  1084 SPHHPPVPTS------TSAASASV---GRPDF-GLISHQFEDERAHMLRDDRVRYFGMHPHLAAP 1138

  Fly  2440 SMGQQSVSAKKESDHTMGIVSN-----AGVGLSS------------------VPGGVIGISP--- 2478
            .:...|.:|..|..|. |::|:     ||....:                  ||.|::..:|
Zfish  1139 HLSSPSHAAHLEQLHA-GLLSHSHLHPAGAAAQASHHPDFYSRLGHLHSHPHVPNGILTKTPNLV 1202

  Fly  2479 --VSSVAPSR 2486
              :|..||.|
Zfish  1203 GALSIGAPPR 1212

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tay	NP_001259585.1	Auts2	1900..>1922	CDD:291981	14/26 (54%)
fbrs	XP_003199661.2	Auts2	550..765	CDD:291981	61/255 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	46	1.000	Domainoid score	I12098
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	156	1.000	Inparanoid score	I4254
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	3.050