Protein Alignment tay and auts2

DIOPT Version :9

• Sequence 1: NP_001259585.1
• Gene: tay / 32547
• FlyBaseID: FBgn0260938
• Length: 2486
• Species: Drosophila melanogaster
• Sequence 2: XP_031752079.1
• Gene: auts2 / 100498056
• XenbaseID: XB-GENE-987496
• Length: 1045
• Species: Xenopus tropicalis
• Alignment Length: 1045
• Identity: 244/1045 - (23%)
• Similarity: 370/1045 - (35%)
• Gaps: 376/1045 - (35%)

  Fly  1577 TPVLSSSSSM---PPGLG---NLSSYSSKAALWLNSPANAVVTTCAPTTPIVSSGSARPTPPLSN 1635
            ||||.|..::   ||...   :|.||:| ::|.:||                .|.|...||..|.
 Frog   159 TPVLPSPPTVQQRPPSQNLPQSLCSYNS-SSLSVNS----------------LSSSRSSTPAKSQ 206

  Fly  1636 CTSMGIGMVNAASTARSSCNAISPLSIPATAGIHVSATNPSFQ--SSSYFPTPLAPPPSSPSPAT 1698
            .||..:|...:.|.        .|||:|:.:.:|  ...|:.|  :..:.|...|||.:.|.|
 Frog   207 ATSSHLGHHPSTSP--------YPLSLPSHSPLH--RFTPTLQPPAHQHHPNMFAPPTALPPP-- 259

  Fly  1699 SSAAIISSSASQFNPAVSHSMSSIVTTAGATTTTASSVTQPSVAAISNPVTNTPHPFSAESLFQP 1763
                          |.:                |:.::..|.            ||  |.|.:
 Frog   260 --------------PPL----------------TSGTLQVPG------------HP--ANSTY-- 278

  Fly  1764 SKNDQADLLRRELDSRFL-----DRSGLAVTPTPPSSTYLRTDL---QHQ-QHAHLHQH------ 1813
               .:.||||:||::|||     || |.::.|.|    ||||:.   ||| ||.|.|||
 Frog   279 ---SEQDLLRQELNTRFLASQSADR-GASLGPPP----YLRTEFHQHQHQHQHQHTHQHTHQHTF 335

  Fly  1814 ---PQLLPPVSAPSTPLSAVQPSSGQIFPPPLFKDISKISSVDPQFYRTGM---------GLPP- 1865
               |..:||.:...||            .||:|....  :.||| |||..:         |:||
 Frog   336 TPFPHAIPPTAIMPTP------------APPMFDKYP--TKVDP-FYRHSLFHSYPPAVSGIPPM 385

  Fly  1866 -----------GGYSGYTSAGLLHSGLGGPTPF----MPPNHLTSFAP--KKTGRWNAMHVRIAW 1913
                       |.:...||..:..:|..|..|.    ..|.....|.|  :|.|:|.||||.|||
 Frog   386 IPPTGPFGSLQGAFQPKTSNPIDVAGRPGTVPHTLLQKDPRLTDPFRPMLRKPGKWCAMHVHIAW 450

  Fly  1914 EIYYHQNKQSPEKQ-----------PGF---PTASSNAGSINA-PIP-----PGNMISGGGGGMA 1958
            :||:||.|...:.|           |.|   |...|..|:|:. |.|     |..:.|..||
 Frog   451 QIYHHQQKVKKQMQTDPHKLDFGLKPEFLSRPPGPSLFGAIHPHPHPHDLARPSTLFSAAGG--- 512

  Fly  1959 SGASTPVNNVAAIPAVGGGVLVSNGPPSVLGMKTTPTLGMSSTPQHILHRASEMPPSAAF----- 2018
                   .:.||.|.         |||.                    |.::.:.|||..
 Frog   513 -------THPAAAPF---------GPPP--------------------HHSNFLNPSAHLEQFNR 541

  Fly  2019 PGGLPGRLAFETSPLAASFIGAPPSHIGTAVSPFGRYVTPFGFTGLTHFGGHLDSWRTNAMQRSV 2083
            |....|..|...|  |...:|.|..   |:.|.|.....|    .:..|....:.|  |.:.|:
 Frog   542 PSTFSGLAAVGGS--AFGGLGNPSV---TSNSMFSHKEGP----NMQSFNNPHEPW--NRLHRT- 594

  Fly  2084 AYHPSSAAPSPNW--PVKSD--PGLDNARREAEERERELRDREQRERDRQR-------------- 2130
               |.|....|.|  |.:|:  ..:.:..|:|::||...:|.::||...:|
 Frog   595 ---PPSFPTPPPWLKPGESERSSSVASHERDADKRETATKDDKERENVEKRHSSHPSPAPINQVN 656

  Fly  2131 -----REREERERKEKEEKLKREQQERERERERDRKERE---RERREIERREMERERMLQQQR-I 2186
                 |...|:.|......::.:::.:|||||.....:|   .|.:..:...:|::.::.:.| |
 Frog   657 STGHNRSLSEQNRNNLNNDVREKEKPKEREREHSDSWKEASIEEHKTKDNHILEKDNLVHESRTI 721

  Fly  2187 NESNKQAAVQAAAAATAPVRDRSPHRNVG---ELNTE----------IRIKEEHPRTKEEQDVM- 2237
            :|:.:...|.:.......:.:..|:.|..   |..||          :::|||.   |||.|::
 Frog   722 DEAKQLNRVPSPYVRPPTMENTRPNSNSNRETERKTETYDNQKKSNDVKVKEER---KEEHDIVV 783

  Fly  2238 -----LLRASAAAVGVGDPRYHSSSLAAAQASAAAAAAHHHHANFMAASRHGLPPPPS--HLTRT 2295
                 :.|.|.....:.....|.|.||:...:...|..|               |..|  .|.||
 Frog   784 PDGSQIHRTSEQPPPISTSNVHPSHLASLPMAMGVAGMH---------------PMNSIGGLDRT 833

  Fly  2296 -MMPPTLSVGGPITHFGAPAPPG---------WG--IDPYRDPY---PILRYNPI-MEAALRHEA 2344
             ||.|.:.:        :|.|.|         |.  .||.||||   .|.|.:|: .:..||::.
 Frog   834 RMMTPFMGI--------SPIPGGERFPYPSFHWDPMRDPLRDPYRGLDIHRRDPLGRDFLLRNDP 890

  Fly  2345 EERQKAINIYAAQSA---------------------------AHLRSKE---------------- 2366
            ..|..|..:|.|:.:                           :||..:|
 Frog   891 LHRLTAPRLYEAERSFRDREPHDYNHHHHHLAVDPRREHERVSHLEERERLHMLREDYEHARLHA 955

  Fly  2367 --PSPIP-----PSVGSLGPPPPHHRLQIVSSVAQSGVQQPGPPSQQQQQQMSSGGGMVKNSGGP 2424
              |:.:.     ||:.:.|.|..|:.....::..|:|:....||:    ..:|:...::...||
 Frog   956 VHPAALDGHLPHPSLITPGLPSMHYARVSPTTGHQNGILNKTPPT----AALSAPPPLISTLGG- 1015

  Fly  2425 QAPGS 2429
             .|||
 Frog  1016 -RPGS 1019

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tay	NP_001259585.1	Auts2	1900..>1922	CDD:291981	14/21 (67%)
auts2	XP_031752079.1	Auts2	437..649	CDD:405922	67/265 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	46	1.000	Domainoid score	I11940
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	144	1.000	Inparanoid score	I4343
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002036
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5721
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.080