DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Myb and REB1

DIOPT Version :9

Sequence 1:	NP_511170.1	Gene:	Myb / 32543	FlyBaseID:	FBgn0002914	Length:	657	Species:	Drosophila melanogaster
Sequence 2:	NP_009605.1	Gene:	REB1 / 852338	SGDID:	S000000253	Length:	810	Species:	Saccharomyces cerevisiae

Alignment Length:	401	Identity:	78/401 - (19%)
Similarity:	146/401 - (36%)	Gaps:	112/401 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 SASTENGEELMN--------YGSNSDSEESEYSENEDTQVCDKDSQQNSNADSGYPLDS------ 53
            :|.|::.|:|.:        :|.|..::    :.|:||......::|.|.......|||
Yeast   274 AADTDDNEKLKHIKDHLMRTHGLNHQNK----NHNDDTDDLSNSTKQYSELQKDSMLDSSLNKSR 334

  Fly    54 ------PEL--QDSKTTGQKG---QNKSGKT----------------------SIGAVHPN---Y 82
                  |::  ||::...||.   .|::|..                      |..:..|:   .
Yeast   335 NYMEVLPKVISQDTQPHQQKSPSHDNEAGSVDNSEISQLLQSAATKASSLVSLSSSSATPSTSRS 399

  Fly    83 GFGKRWSKSEDVLLKQLVETHGENWEIIGPHFKDRL-EQQVQQR-WA-------------KVL-- 130
            ...|.:.|:||..|::.:    ..:|.|     :|| .|||.:| |:             |||
Yeast   400 NNSKAFDKAEDAALERFI----NEYEAI-----ERLTRQQVCERIWSSDRPKDNFWNNIYKVLPY 455

  Fly   131 --NPELIK------------GPWTRDEDDMVIKLVRNFGPKKWTLIARYLNGRIGKQCRERWHNH 181
              :..:.|            |.||.:|:..:.||... ...:|..|.:.| ||:.:.||:||.|:
Yeast   456 RSSSSIYKHMRRKYHIFEQRGKWTAEEEQELAKLCAE-KEGQWAEIGKTL-GRMPEDCRDRWRNY 518

  Fly   182 L--NPNIKKTAWTEKEDEIIYQAHLELGNQWAKIAKRLPGRTDNAIKNHWNSTMRRKYDVERRSV 244
            :  ..|.....|:.:|:|::.:.          |:..|........:.|.|.....::.::....
Yeast   519 VKCGTNRASNRWSVEEEELLKKV----------ISDMLEEAQQQQSQLHPNLLEEEQHLLQDDQN 573

  Fly   245 NASGSDLKSSRTHLITLIKSGGISKCMNNMQHNKESGGEAVNKSENADGASVTAVKGGDLAQES- 308
            :...:|.....|.......:..|.:....:|..::...:|:..:..|..:|:...|..|...:|
Yeast   574 DHRNNDEDDDDTASAAAAAAAAIQEQQQLLQQKQQDDDDAIAAAAAAASSSLGDNKDEDKPHDSL 638

  Fly   309 ---QDDHQKGS 316
               .||:.:.|
Yeast   639 GIQLDDNSQNS 649

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Myb	NP_511170.1	SANT	85..132	CDD:197842	17/65 (26%)
		Myb_DNA-bind_6	88..147	CDD:290632	21/89 (24%)
		SANT	136..184	CDD:197842	17/61 (28%)
		Myb_DNA-bind_6	139..197	CDD:290632	18/59 (31%)
		SANT	188..235	CDD:197842	7/46 (15%)
		Myb_DNA-binding	188..233	CDD:278669	7/44 (16%)
		Cmyb_C	388..530	CDD:286408
REB1	NP_009605.1	REB1	202..701	CDD:227476	78/401 (19%)
REB1	NP_009605.1	SANT	<691..719	CDD:197842
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157344736
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5147
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2047
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.860